ChemicalBook > CAS DataBase List > (3S,7S,8S,9S,10R,13R,14S,17R)-17-[(2R)-7-hydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
(3S,7S,8S,9S,10R,13R,14S,17R)-17-[(2R)-7-hydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
- Product Name
- (3S,7S,8S,9S,10R,13R,14S,17R)-17-[(2R)-7-hydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
- CAS No.
- 4725-24-0
- Chemical Name
- (3S,7S,8S,9S,10R,13R,14S,17R)-17-[(2R)-7-hydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
- Synonyms
- Cholesterol Impurity 34;7α,27-dihydroxycholesterol;cholest-5-ene-3,7,27-triol;7alpha,26-dihydroxycholesterol;7-alpha,27-Dihydroxycholesterol;Cholest-5-ene-3,7,26-triol, (3β,7α)-;(3S,7S,8S,9S,10R,13R,14S,17R)-17-[(2R)-7-hydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
- CBNumber
- CB31235639
- Molecular Formula
- C27H46O3
- Formula Weight
- 418.65
- MOL File
- 4725-24-0.mol
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(3S,7S,8S,9S,10R,13R,14S,17R)-17-[(2R)-7-hydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol Property
- Boiling point:
- 552.6±35.0 °C(Predicted)
- Density
- 1.08±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- pka
- 14.11±0.70(Predicted)
- form
- powder
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- LIP0002865
- Product name
- 7-ALPHA-27-DIHYDROXYCHOLESTEROL
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.34
- Updated
- 2021/12/16
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(3S,7S,8S,9S,10R,13R,14S,17R)-17-[(2R)-7-hydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol Chemical Properties,Usage,Production
Uses
7α,27-Dihydroxycholesterol is used in the study of immunochemistry. It is a potent and selective agonist of EB12.7α,27-Dihydroxycholesterol is also studied in biochemical methods as one of several oxysterols found in human plasma using HPLC-MS and incorporating charg-tagging and high-resolution mass spectrometry.
Definition
ChEBI: An oxysterol that is cholesterol which is substituted by hydroxy groups at the 7alpha and 26 positions.
Biological Activity
7α,27-dihydroxycholesterol (7α,27-di-OHC) is one of the metabolite screened in pathological conditions such as neurological diseases, Smith-Lemli-Opitz syndrome, obesity metabolic syndrome and diabetes by lipidomics analysis of human specimens. Upon the lipopolysaccharide activation, the levels of 7α,27-di-OHC decreases.7α27-OHC is a ligand for Epstein-Barr virus-induced gene 2 (EBI2).
(3S,7S,8S,9S,10R,13R,14S,17R)-17-[(2R)-7-hydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol Preparation Products And Raw materials
Raw materials
Preparation Products
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(3S,7S,8S,9S,10R,13R,14S,17R)-17-[(2R)-7-hydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol Suppliers
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