ChemicalBook > CAS DataBase List > PROGLUMIDE, SODIUM SALT
PROGLUMIDE, SODIUM SALT
- Product Name
- PROGLUMIDE, SODIUM SALT
- CAS No.
- 99247-33-3
- Chemical Name
- PROGLUMIDE, SODIUM SALT
- Synonyms
- PROGLUMIDE SODIUM;PROGLUMIDE, SODIUM SALT;Proglumide sodium salt solid;4-benzamido-5-(dipropylamino)-5-oxopentanoate;PROGLUMIDE SODIUM SALT SELECTIVE CHOLECY STOK;dl-4-benzamido-n,n-dipropylglutaramicacidsodiumsalt;SODIUM;4-BENZAMIDO-5-(DIPROPYLAMINO)-5-OXOPENTANOATE;4-benzamido-n,n-dipropyl-,sodiumsalt,dl-glutaramicaci;4-BENZOYLAMINO-5-DIPROPYLAMINO-5-OXOPENTANOIC ACID SODIUM;Glutaramic acid, 4-benzamido-N,N-dipropyl-, sodium salt, DL-
- CBNumber
- CB3125814
- Molecular Formula
- C18H27N2NaO4
- Formula Weight
- 358.41
- MOL File
- 99247-33-3.mol
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PROGLUMIDE, SODIUM SALT Property
- storage temp.
- Desiccate at RT
- solubility
- H2O: soluble
- form
- solid
- color
- white
- Water Solubility
- Soluble to 100 mM in water
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- M006
- Product name
- Proglumide sodium salt
- Purity
- solid
- Packaging
- 100mg
- Price
- $184
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- M006
- Product name
- Proglumide sodium salt
- Purity
- solid
- Packaging
- 500mg
- Price
- $1160
- Updated
- 2025/07/31
Tocris
- Product number
- 1478
- Product name
- Proglumide sodium salt
- Purity
- ≥98%(HPLC)
- Packaging
- 50
- Price
- $64
- Updated
- 2021/12/16
Usbiological
- Product number
- 256329
- Product name
- Proglumide sodium salt
- Packaging
- 50mg
- Price
- $290
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- API0014081
- Product name
- PROGLUMIDE SODIUM SALT
- Purity
- 99.00%
- Packaging
- 5MG
- Price
- $503.68
- Updated
- 2021/12/16
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PROGLUMIDE, SODIUM SALT Chemical Properties,Usage,Production
Uses
Proglumide sodium salt has been used to study the effects of proglumide on macronutrient selection in European sea bass Dicentrarchus labrax, L.
Biochem/physiol Actions
Proglumide sodium salt is a non-peptide cholecystokinin receptor antagonist that has greater selectivity for the CCKA subtype. It selectively blocks central nervous system effects. Proglumide sodium salt is orally active.
in vivo
Proglumide (250-750 mg/kg; intraperitoneal injection; adult male Sprague Dawley rats) treatment is significantly effective in ameliorating the seizure activities, cognitive dysfunctions, and cerebral oxidative stress[1].
| Animal Model: | Adult male Sprague Dawley rats (200-250?g; 2 months old) are induced status epilepticus (SE)[1] |
| Dosage: | 250 mg/kg, 500 mg/kg, and 750?mg/kg |
| Administration: | Intraperitoneal injection |
| Result: | Dose-dependently and significantly increased the latencies to seizure and SE. Significantly and dose-dependently attenuated Li-PC (SE) induced increase in thiobarbituric acid (TBARS) and catalase (CAT), attenuated Li-Pc induced decrease in SOD, and attenuated depletion of GSH and glutathione-S transferase (GST) in the hippocampus and striatum. |
storage
Desiccate at RT
PROGLUMIDE, SODIUM SALT Preparation Products And Raw materials
Raw materials
Preparation Products
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99247-33-3, PROGLUMIDE, SODIUM SALTRelated Search:
COCOAMINE ACETATE
N-Acetylsulfanilyl chloride
2-Ethoxybenzamide
Proglumide
N2-BENZYL-N1,N1-DIETHYL-1,2-PROPANEDIAMINE
N,N-Dipropylpropionamide
LORGLUMIDE
PROGLUMIDE, SODIUM SALT