Podophyllotoxone

Product Name: Podophyllotoxone
CAS No.: 477-49-6
Chemical Name: Podophyllotoxone
Synonyms: Podophyllotoxone;Podophyllotoxinone;(-)-podophyllotoxon;(-)-podophyllotoxon;Podophyllotoxone, 10 mM in DMSO;Inhibitor,DU145,inhibit,Podophyllotoxone,cancer,Microtubule/Tubulin,PC3,cells,prostate;(5R)-5aα,8aβ-Dihydro-5β-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxole-6,9(5H,8H)-dione;(5R)-5,5aα,8,8aβ-Tetrahydro-5β-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxole-6,9-dione;(5aR)-5aα,6,8aβ,9-Tetrahydro-9α-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxole-5,8-dione;(5R)-5β-(3,4,5-Trimethoxyphenyl)-5,8,8aβ,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d]-1,3-dioxole-6,9(5aαH)-dione
CBNumber: CB31267854
Molecular Formula: C22H20O8
Formula Weight: 412.39
MOL File: 477-49-6.mol

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Podophyllotoxone Property

Melting point:: 191.73℃
Boiling point:: 602.3±55.0 °C(Predicted)
Density: 1.365±0.06 g/cm3 (20 ºC 760 Torr)
storage temp.: 4°C, away from moisture and light
solubility: DMSO : 100 mg/mL (242.49 mM; Need ultrasonic)
form: Solid
color: White to off-white
InChI: InChI=1S/C22H20O8/c1-25-16-4-10(5-17(26-2)21(16)27-3)18-11-6-14-15(30-9-29-14)7-12(11)20(23)13-8-28-22(24)19(13)18/h4-7,13,18-19H,8-9H2,1-3H3/t13-,18+,19-/m0/s1
InChIKey: ISCQYPPCSYRZOT-BKTGTZMESA-N
SMILES: O1C2=CC3=C(C=C2OC1)C(=O)[C@@]1([H])COC(=O)[C@]1([H])[C@@H]3C1=CC(OC)=C(OC)C(OC)=C1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: P681020
Product name: Podophyllotoxone
Packaging: 1g
Price: $1320
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 72055
Product name: Podophyllotoxone
Packaging: 1g
Price: $2200
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: TOX0000167
Product name: PODOPHYLLOTOXONE
Purity: 95.00%
Packaging: 5MG
Price: $498.88
Updated: 2021/12/16

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Podophyllotoxone Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, from the rhizomes of Sinopodophyllum hexandrum (Royle) Ying (highest content in Anhui) and Dysosma versipellis (Hance) M. Cheng ex Ying (highest content in Anhui). (highest content from Anhui).

Uses

Podophyllotoxone is a naturally occurring flavonoid that shown significant cell apoptosis and antiproliferative affect against human PC-3 and Bcap-37 cancer cell lines

Definition

ChEBI: Podophyllotoxone is a lactone and a lignan.

Podophyllotoxone Preparation Products And Raw materials

Raw materials

Preparation Products

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Podophyllotoxone Suppliers

Canada 1 China 60 India 2 United States 7 Global 70

Huzhou ZhanShu Biotechnology Co.,Ltd

Tel: 0572-8889530 18167260939
Email: zsubio@163.com
Country: China
ProdList: 392
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chengdu Biopurify Phytochemicals Ltd.

Tel: +86-028-82633397 18982077548
Fax: +86-28-82633165
Email: cwb1@biopurify.cn
Country: China
ProdList: 2376
Advantage: 60

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3988
Advantage: 66

Chengdu Herbpurify Co.Ltd.

Tel: 2355253622; 18981954830
Fax: 086-28-85377358
Email: 2355253622@qq.com;
Country: China
ProdList: 1103
Advantage: 58

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18333
Advantage: 56

Wuhan ChemFaces Biochemical Co., Ltd.

Tel: 18607101326 15172504745
Fax: +86-27-84254680
Email: aileen@chemfaces.com
Country: China
ProdList: 6905
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Shandong Xiya Chemical Co., Ltd.

Tel: 4009903999 13395398332
Fax: 0539-6365991
Email: sales@xiyashiji.com
Country: China
ProdList: 20794
Advantage: 60

Shanghai SuperLan Chemcial Technique Centre

Tel: 0-2022843681 15618226720
Fax: +86-21-51601218
Email: chaolaichem@foxmail.com
Country: China
ProdList: 10410
Advantage: 58

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View Lastest Price from Podophyllotoxone manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: podophyllotoxone 477-49-6
Price: US $30.00-20.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200000KG
Release date: 2024-08-06

477-49-6, PodophyllotoxoneRelated Search:

Acetylepipodophyllotoxin KAEMPFEROL-3,7,4'-TRIMETHYL ETHER HOMOARBUTIN clerodendrin Quillaic acid Taccalonolide A Podophyllotoxone

Podophyllotoxone

(5aR)-5aα,6,8aβ,9-Tetrahydro-9α-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxole-5,8-dione

(5R)-5,5aα,8,8aβ-Tetrahydro-5β-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxole-6,9-dione

(5R)-5,8,8aβ,9-Tetrahydro-5β-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxole-6(5aαH),9-dione

(5R)-5aα,8aβ-Dihydro-5β-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxole-6,9(5H,8H)-dione

(5R)-5β-(3,4,5-Trimethoxyphenyl)-5,8,8aβ,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d]-1,3-dioxole-6,9(5aαH)-dione

Podophyllotoxinone

(-)-podophyllotoxon

Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxole-5,8-dione, 5a,6,8a,9-tetrahydro-9-(3,4,5-trimethoxyphenyl)-, (5aR,8aR,9R)-

(-)-podophyllotoxon

(5aR,8aR,9R)-9-(3,4,5-Trimethoxyphenyl)-5a,6,8a,9-tetrahydrofuro[3′,4′:6,7]naphtho[2,3- d][1,3]dioxole-5,8-dione

Inhibitor,DU145,inhibit,Podophyllotoxone,cancer,Microtubule/Tubulin,PC3,cells,prostate

Podophyllotoxone, 10 mM in DMSO

477-49-6