ChemicalBook > CAS DataBase List > osthenol

osthenol

Product Name
osthenol
CAS No.
484-14-0
Chemical Name
osthenol
Synonyms
NSC 625328;7-Hydroxy-8-prenylcoumarin;7-Hydroxy-8-isopentenyl-2H-1-benzopyran-2-one;7-Hydroxy-8-(3-methyl-2-butenyl)-2H-1-benzopyran-2-one;2H-1-Benzopyran-2-one, 7-hydroxy-8-(3-methyl-2-buten-1-yl)-;inhibit,selective,Monoamine Oxidase,MAO,depression,competitive,Osthenol,Inhibitor,coumarin,Ostenol
CBNumber
CB31312338
Molecular Formula
C14H14O3
Formula Weight
230.26
MOL File
484-14-0.mol
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osthenol Property

Melting point:
89-91 °C
Boiling point:
422.8±45.0 °C(Predicted)
Density 
1.203±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
form 
Solid
pka
8.45±0.20(Predicted)
color 
White to yellow
LogP
3.342 (est)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0022826
Product name
Osthenol
Purity
98.91%
Packaging
1mg
Price
$120
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0001863
Product name
OSTHENOL
Purity
95.00%
Packaging
5MG
Price
$499
Updated
2021/12/16
Arctom
Product number
SY232770
Product name
Damascenone
Purity
≥98%
Packaging
10mg
Price
$190.91
Updated
2021/12/16
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osthenol Chemical Properties,Usage,Production

Chemical Properties

Soluble in methanol, ethanol, DMSO and other organic solvents, derived from Rhizoma et Radix Notopterygii.

Definition

ChEBI: Osthenol is a hydroxycoumarin that is umbelliferone in which the hydrogen at position 8 has been replaced by a prenyl group. It has a role as a plant metabolite and an antifungal agent. It is functionally related to an umbelliferone.

Biological Activity

Ostenol (Ostenol), a preacylated coumarin isolated from the dried roots of Ostonia, is a reversible, selective and competitive inhibitor of human monoamine oxidase-A (hMAO-A) (Ki=0.26 μM) . Oshenol has a potential selective inhibitory effect on recombinant hMAO-A with IC50 of 0.74 μM, showing a high selectivity index for hMAO-A and hMAO-B.

osthenol Preparation Products And Raw materials

Raw materials

Preparation Products

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  • 7-Hydroxy-8-(3-methyl-2-butenyl)-2H-1-benzopyran-2-one
  • 7-Hydroxy-8-isopentenyl-2H-1-benzopyran-2-one
  • 7-Hydroxy-8-prenylcoumarin
  • NSC 625328
  • 2H-1-Benzopyran-2-one, 7-hydroxy-8-(3-methyl-2-buten-1-yl)-
  • inhibit,selective,Monoamine Oxidase,MAO,depression,competitive,Osthenol,Inhibitor,coumarin,Ostenol
  • 484-14-0