ChemicalBook > CAS DataBase List > 1-formylisoquinoline thiosemicarbazone
1-formylisoquinoline thiosemicarbazone
- Product Name
- 1-formylisoquinoline thiosemicarbazone
- CAS No.
- 2365-26-6
- Chemical Name
- 1-formylisoquinoline thiosemicarbazone
- Synonyms
- IQ-1;1-formylisoquinoline thiosemicarbazone;1-Isoquinolinecarbaldehyde thiosemicarbazone;Hydrazinecarbothioamide, 2-(1-isoquinolinylmethylene)-
- CBNumber
- CB31313911
- Molecular Formula
- C11H10N4S
- Formula Weight
- 230.29
- MOL File
- 2365-26-6.mol
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1-formylisoquinoline thiosemicarbazone Property
- Density
- 1.2608 (rough estimate)
- refractive index
- 1.5500 (estimate)
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Safety
- Toxicity
- LD50 intraperitoneal in mouse: 800mg/kg
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N-Bromosuccinimide Price
Tocris
- Product number
- 4713
- Product name
- IQ1
- Purity
- ≥99%(HPLC)
- Packaging
- 10
- Price
- $189
- Updated
- 2021/12/16
Usbiological
- Product number
- I8565
- Product name
- IQ-1
- Packaging
- 1mg
- Price
- $363
- Updated
- 2021/12/16
Usbiological
- Product number
- 255520
- Product name
- IQ 1
- Packaging
- 10mg
- Price
- $446
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- CHM1003817
- Product name
- 1-FORMYLISOQUINOLINE THIOSEMICARBAZONE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $504.11
- Updated
- 2021/12/16
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1-formylisoquinoline thiosemicarbazone Chemical Properties,Usage,Production
Uses
IQ 1 disrupts Wnt signaling. IQ-1 in conjunction with Wnt3a has been shown to be sufficient to maintain murine embryonic stem cell proliferation in the absence of serum. Binds to the PR72/PR130 subunit of protein phosphatase PP2A preventing β-catenin from switching co-activator usage from CBP to p300 leading to an increase in β-catenin/CBP-driven transcription at the expense of β-catenin/p300-driven transcription.
1-formylisoquinoline thiosemicarbazone Preparation Products And Raw materials
Raw materials
Preparation Products
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