ChemicalBook > CAS DataBase List > 1-formylisoquinoline thiosemicarbazone

1-formylisoquinoline thiosemicarbazone

Product Name
1-formylisoquinoline thiosemicarbazone
CAS No.
2365-26-6
Chemical Name
1-formylisoquinoline thiosemicarbazone
Synonyms
IQ-1;1-formylisoquinoline thiosemicarbazone;1-Isoquinolinecarbaldehyde thiosemicarbazone;Hydrazinecarbothioamide, 2-(1-isoquinolinylmethylene)-
CBNumber
CB31313911
Molecular Formula
C11H10N4S
Formula Weight
230.29
MOL File
2365-26-6.mol
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1-formylisoquinoline thiosemicarbazone Property

Density 
1.2608 (rough estimate)
refractive index 
1.5500 (estimate)
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Safety

Toxicity
LD50 intraperitoneal in mouse: 800mg/kg
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
4713
Product name
IQ1
Purity
≥99%(HPLC)
Packaging
10
Price
$189
Updated
2021/12/16
Usbiological
Product number
I8565
Product name
IQ-1
Packaging
1mg
Price
$363
Updated
2021/12/16
Usbiological
Product number
255520
Product name
IQ 1
Packaging
10mg
Price
$446
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM1003817
Product name
1-FORMYLISOQUINOLINE THIOSEMICARBAZONE
Purity
95.00%
Packaging
5MG
Price
$504.11
Updated
2021/12/16
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1-formylisoquinoline thiosemicarbazone Chemical Properties,Usage,Production

Uses

IQ 1 disrupts Wnt signaling. IQ-1 in conjunction with Wnt3a has been shown to be sufficient to maintain murine embryonic stem cell proliferation in the absence of serum. Binds to the PR72/PR130 subunit of protein phosphatase PP2A preventing β-catenin from switching co-activator usage from CBP to p300 leading to an increase in β-catenin/CBP-driven transcription at the expense of β-catenin/p300-driven transcription.

1-formylisoquinoline thiosemicarbazone Preparation Products And Raw materials

Raw materials

Preparation Products

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2365-26-6, 1-formylisoquinoline thiosemicarbazoneRelated Search:

1-formylisoquinoline thiosemicarbazone 2-Formylpyridine thiosemicarbazone

  • 1-formylisoquinoline thiosemicarbazone
  • 1-Isoquinolinecarbaldehyde thiosemicarbazone
  • IQ-1
  • Hydrazinecarbothioamide, 2-(1-isoquinolinylmethylene)-
  • 2365-26-6