ChemicalBook > CAS DataBase List > 5-CHLORO-1-METHYL-1H-INDOLE-2-CARBOXYLIC ACID

5-CHLORO-1-METHYL-1H-INDOLE-2-CARBOXYLIC ACID

Product Name
5-CHLORO-1-METHYL-1H-INDOLE-2-CARBOXYLIC ACID
CAS No.
59908-47-3
Chemical Name
5-CHLORO-1-METHYL-1H-INDOLE-2-CARBOXYLIC ACID
Synonyms
AKOS JY2082728;TIMTEC-BB SBB011233;ASINEX-REAG BAS 10142185;5-chloro-1-methyl-2-indolecarboxylic acid;5-chloro-1-methylindole-2-carboxylic acid;5-CHLORO-1-METHYL-1H-INDOLE-2-CARBOXYLIC ACID;1H-Indole-2-carboxylic acid, 5-chloro-1-Methyl-;5,7-diethyl-2-(3-nitrophenyl)-1,3-diazaadamantan-8-one
CBNumber
CB3131970
Molecular Formula
C10H8ClNO2
Formula Weight
209.63
MOL File
Mol file
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5-CHLORO-1-METHYL-1H-INDOLE-2-CARBOXYLIC ACID Property

Boiling point:
420.6±25.0 °C(Predicted)
Density 
1.39±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
3.93±0.30(Predicted)
Appearance
White to light yellow Solid
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
22
HazardClass 
IRRITANT
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P403Store in a well-ventilated place.

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N-Bromosuccinimide Price

TRC
Product number
C994855
Product name
5-Chloro-1-methyl-1H-indole-2-carboxylicAcid
Packaging
10mg
Price
$45
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC118365
Product name
5-Chloro-1-methyl-1H-indole-2-carboxylic acid
Packaging
100mg
Price
$58
Updated
2021/12/16
ChemScene
Product number
CS-W006501
Product name
5-Chloro-1-methyl-1H-indole-2-carboxylicacid
Packaging
250mg
Price
$63
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC118365
Product name
5-Chloro-1-methyl-1H-indole-2-carboxylic acid
Packaging
250mg
Price
$115
Updated
2021/12/16
AK Scientific
Product number
8930AB
Product name
5-Chloro-1-methyl-1H-indole-2-carboxylicacid
Packaging
250mg
Price
$145
Updated
2021/12/16
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5-CHLORO-1-METHYL-1H-INDOLE-2-CARBOXYLIC ACID Chemical Properties,Usage,Production

Synthesis

148356-79-0

59908-47-3

Step 2: Synthesis of 5-chloro-1-methyl-1H-indole-2-carboxylic acid (43.2) To a THF solution (10 mL) of methyl 5-chloro-1-methyl-1H-indole-2-carboxylate (43.1, 224 mg) was added an aqueous solution (2 mL) of LiOH (36 mg, 1.5 mmol). The reaction mixture was stirred at room temperature for 2 hours. Upon completion of the reaction, the solvent was removed under reduced pressure and the residue was dissolved in 1N aqueous hydrochloric acid solution (10 mL). The resulting suspension was allowed to stand for 10 minutes, then filtered through filter paper, collected as a solid and dried under vacuum to afford 163 mg (77.6% yield) of 5-chloro-1-methyl-1H-indole-2-carboxylic acid (43.2) as a beige powder.

References

[1] Patent: KR101725451, 2017, B1. Location in patent: Paragraph 0294; 0301-0303
[2] Patent: WO2016/40449, 2016, A1. Location in patent: Paragraph 00508-00509
[3] Patent: WO2006/66879, 2006, A2. Location in patent: Page/Page column 53; 48
[4] Bioorganic and Medicinal Chemistry, 2018, vol. 26, # 21, p. 5664 - 5671

5-CHLORO-1-METHYL-1H-INDOLE-2-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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5-CHLORO-1-METHYL-1H-INDOLE-2-CARBOXYLIC ACID Suppliers

J & K SCIENTIFIC LTD.
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View Lastest Price from 5-CHLORO-1-METHYL-1H-INDOLE-2-CARBOXYLIC ACID manufacturers

Career Henan Chemical Co
Product
5-CHLORO-1-METHYL-1H-INDOLE-2-CARBOXYLIC ACID 59908-47-3
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customized
Release date
2020-03-05

59908-47-3, 5-CHLORO-1-METHYL-1H-INDOLE-2-CARBOXYLIC ACIDRelated Search:


  • TIMTEC-BB SBB011233
  • AKOS JY2082728
  • 5-CHLORO-1-METHYL-1H-INDOLE-2-CARBOXYLIC ACID
  • ASINEX-REAG BAS 10142185
  • 1H-Indole-2-carboxylic acid, 5-chloro-1-Methyl-
  • 5-chloro-1-methylindole-2-carboxylic acid
  • 5-chloro-1-methyl-2-indolecarboxylic acid
  • 5,7-diethyl-2-(3-nitrophenyl)-1,3-diazaadamantan-8-one
  • 59908-47-3