1-(4-BROMO-2-THIENYL)ETHAN-1-ONE
- Product Name
- 1-(4-BROMO-2-THIENYL)ETHAN-1-ONE
- CAS No.
- 7209-11-2
- Chemical Name
- 1-(4-BROMO-2-THIENYL)ETHAN-1-ONE
- Synonyms
- AKOS B020506;BUTTPARK 95\04-34;ART-CHEM-BB B020506;2-ACETYL-4-BROMOTHIOPHENE;4-Bromo-2-acetylthiophene;2-Acetyl-4-bromothiophene 97%;1-(4-Bromothien-2-yl)ethanone;1-(4-Bromo-2-Thienyl)Ethanone;4-bromo-2-acetylthiophene 1-(4-BROMO-2-THIENYL)ETHAN-1-ONE
- CBNumber
- CB3132568
- Molecular Formula
- C6H5BrOS
- Formula Weight
- 205.07
- MOL File
- 7209-11-2.mol
1-(4-BROMO-2-THIENYL)ETHAN-1-ONE Property
- Boiling point:
- 66-67°C 0,2mm
- Density
- 1.619±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- Appearance
- Colorless to light yellow Liquid
- CAS DataBase Reference
- 7209-11-2(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-36-22
- Safety Statements
- 26-36/37/39
- HazardClass
- IRRITANT
- HS Code
- 29339900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H319Causes serious eye irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B416013
- Product name
- 1-(4-Bromo-2-thienyl)-1-ethanone
- Packaging
- 50mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 042795
- Product name
- 1-(4-Bromo-2-thienyl)-1-ethanone
- Purity
- 95+%
- Packaging
- 1g
- Price
- $24
- Updated
- 2021/12/16
- Product number
- 6H17-9-01
- Product name
- 1-(4-Bromothiophen-2-yl)ethanone
- Purity
- 95%
- Packaging
- 1g
- Price
- $28
- Updated
- 2021/12/16
- Product number
- Y9907
- Product name
- 1-(4-Bromo-2-thienyl)ethan-1-one
- Packaging
- 1g
- Price
- $34
- Updated
- 2021/12/16
- Product number
- FB139732
- Product name
- 1-(4-Bromothiophen-2-yl)ethanone
- Packaging
- 1g
- Price
- $50
- Updated
- 2021/12/16
1-(4-BROMO-2-THIENYL)ETHAN-1-ONE Chemical Properties,Usage,Production
Chemical Properties
Yellow liquid
Synthesis
88-15-3
7209-11-2
General procedure for the synthesis of 4-bromo-2-acetylthiophene from 2-acetylthiophene: In a 250 mL single-necked round-bottomed flask, 2-acetylthiophene (3.00 g, 23.81 mmol), anhydrous aluminum chloride (9.53 g, 71.43 mmol), and carbon tetrachloride (80 mL) were added, and the mixture was cooled to -40 °C. After 10 min, a slow dropwise addition of bromine ( 3.81 g, 23.81 mmol) in carbon tetrachloride (20 mL) was added slowly and stirred at room temperature for 0.5 h after completion of the addition. After 12 hours of reaction, TLC monitoring showed complete consumption of the feedstock. The reaction mixture was carefully poured into a mixture of saturated sodium hydroxide solution and crushed ice and extracted with ethyl acetate (75 mL x 3). The organic phases were combined, washed twice with saturated brine and dried over anhydrous magnesium sulfate. Purification by column chromatography (petroleum ether:ethyl acetate = 500:1) gave a pale yellow oily liquid product (2.74 g) in 72.6% yield.
References
[1] Bioorganic and Medicinal Chemistry Letters, 2004, vol. 14, # 15, p. 4037 - 4043
[2] Journal of Heterocyclic Chemistry, 1982, vol. 19, p. 713 - 716
[3] Patent: CN103408540, 2016, B. Location in patent: Paragraph 0096; 0126; 0127
[4] Chemistry of Heterocyclic Compounds, 2013, vol. 49, # 3, p. 386 - 391
[5] Khim. Geterotsikl. Soedin., 2013, # 3, p. 416 - 422
1-(4-BROMO-2-THIENYL)ETHAN-1-ONE Preparation Products And Raw materials
Raw materials
Preparation Products
1-(4-BROMO-2-THIENYL)ETHAN-1-ONE Suppliers
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