BETA-CYANO-L-ALANINE

Product Name: BETA-CYANO-L-ALANINE
CAS No.: 6232-19-5
Chemical Name: BETA-CYANO-L-ALANINE
Synonyms: H-CPA-OH;3-CYANO-L-ALANINE;(S)-2-Amino-3-cyanopropanoic acid;L-CNAla;H-ALA(3-CN)-OH;H-b-Cyano-Ala-OH;H-β-Cyano-Ala-OH;β-Cyano-L-Ala-OH;H-β-Cyano-Ala-OH;B-cyano-L-alanine
CBNumber: CB3134375
Molecular Formula: C4H6N2O2
Formula Weight: 114.1
MOL File: 6232-19-5.mol

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BETA-CYANO-L-ALANINE Property

Melting point:: 217 °C
storage temp.: -20°C
solubility: PBS (pH 7.2): 10 mg/ml
form: A crystalline solid
color: White to yellow

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C9650
Product name: β-Cyano-L-alanine
Purity: ≥95%
Packaging: 250mg
Price: $611
Updated: 2024/03/01

Cayman Chemical

Product number: 10010947
Product name: β-cyano-L-Alanine
Purity: ≥98%
Packaging: 10mg
Price: $9
Updated: 2024/03/01

Cayman Chemical

Product number: 10010947
Product name: β-cyano-L-Alanine
Purity: ≥98%
Packaging: 50mg
Price: $30
Updated: 2024/03/01

Cayman Chemical

Product number: 10010947
Product name: β-cyano-L-Alanine
Purity: ≥98%
Packaging: 100mg
Price: $50
Updated: 2024/03/01

Cayman Chemical

Product number: 10010947
Product name: β-cyano-L-Alanine
Purity: ≥98%
Packaging: 250mg
Price: $109
Updated: 2024/03/01

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BETA-CYANO-L-ALANINE Chemical Properties,Usage,Production

Description

Hydrogen sulfide (H₂S) is a naturally-occurring gasotransmitter with vasodilator and inflammatory modulating activity. H₂S is synthesized naturally in a range of mammalian tissues principally by the activity of two enzymes, cystathionine γ lyase (CSE) and cystathionine β synthetase (CBS). β-cyano-L-Alanine (BCA) is a reversible inhibitor of the H₂S-synthesizing enzyme CSE. BCA blocks H₂S synthesis in rat liver preparations with an IC₅₀ value of 6.5 μM and increases blood pressure in anaesthetized rats induced with hemorrhagic shock by inhibiting endogenous H₂S synthesis. BCA at 50 mg/kg blocked both L-cysteine- and LPS-induced hyperalgesia in rats.

Chemical Properties

White to off-white powder

Uses

β-L-cyanoalanine is an amino acid that promotes seed germination in A. albus seeds. Beta-Cyano-L-alanine in the diet of adult locusts causes a decrease in the hemolymph volume thereby affecting water balance responses. L-β-cyanoalanine is an inhibitor of vitamin B6.

Definition

ChEBI: A cyanoamino acid that is the 3-cyano-derivative of L-alanine.

Biochem/physiol Actions

β-Cyano-L-alanine (BCA) is used as a cystathione γ-lyase (CSE) inhibitor to study the physiological roles of hydrogen sulfide in processes such as angiogenesis and hypertension.

BETA-CYANO-L-ALANINE Preparation Products And Raw materials

Raw materials

Preparation Products

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BETA-CYANO-L-ALANINE Suppliers

China 33 Germany 1 India 3 Japan 1 Switzerland 2 United Kingdom 2 United States 14 Global 56

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42958
Advantage: 64

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15402
Advantage: 60

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 18209
Advantage: 56

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4428
Advantage: 55

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 18112977050
Email: cb6@aikonchem.com
Country: China
ProdList: 16684
Advantage: 50

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

Shanghai GL Peptide Ltd.

Tel: +86-21-61263340; 17609490614 13764994101
Fax: 021-61263399
Email: fisherwang@glschina.com
Country: China
ProdList: 8466
Advantage: 55

Changzhou Hopschain Chemical Co.,Ltd.

Tel: 0519-85528066 13775048983
Fax: 0519-85528066
Email: sales@hopschem.com
Country: China
ProdList: 31553
Advantage: 55

6232-19-5, BETA-CYANO-L-ALANINERelated Search:

L-Tryptophan Dodecyl acrylate L-Isoleucine N-ALPHA-T-BUTOXYCARBONYL-BETA-CYANO-D-ALANINE,BOC-BETA-CYANO-D-ALANINE N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-BETA-CYANO-D-ALANINE BOC-BETA-CYANO-DL-ALANINE FMOC-BETA-CYANO-L-ALANINE,N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-BETA-CYANO-L-ALANINE N-ALPHA-CARBOBENZOXY-BETA-CYANO-L-ALANINE N-ALPHA-T-BUTOXYCARBONYL-BETA-CYANO-L-ALANINE,BOC-BETA-CYANO-L-ALANINE BETA-CYANO-L-ALANINE H-GLY-GLU-PNA

H-ALA(3-CN)-OH

H-ALA(BETA-CN)-OH

H-BETA-CYANO-ALA-OH

H-BETA-CYANO-L-ALA-OH

BETA-CYANO-ALANINE

BETA-CYANO-L-ALANINE

3-CYANO-L-ALANINE

B-cyano-L-alanine

H-CPA-OH

(2S)-2-amino-3-cyanopropanoic acid

(S)-2-Amino-3-cyanopropanoic acid

H-b-Cyano-Ala-OH

[S,(-)]-3-Cyano-2-aminopropionic acid

L-CNAla

H-β-Cyano-Ala-OH

β-Cyano-L-alanine≥ 98% (TLC)

β-Cyano-L-Ala-OH

L-Alanine, 3-cyano-

β-cyano-L-Alanine

H-β-Cyano-Ala-OH

inhibit,β cyano L Alanine,βcyanoLAlanine,Endogenous Metabolite,Inhibitor

6232-19-5

Biochemicals and Reagents

A - H

Amino Acids and Peptides

BioChemical

Modified Amino Acids

A - H

Amino Acids

Modified Amino Acids