RB 101

Product Name: RB 101
CAS No.: 135949-60-9
Chemical Name: RB 101
Synonyms: RB 101;L-Phenylalanine, N-[2-[[[(2S)-2-aMino-4-(Methylthio)butyl]dithio]Methyl]-1-oxo-3-phenylpropyl]-,phenylMethyl ester
CBNumber: CB31349174
Molecular Formula: C31H38N2O3S3
Formula Weight: 582.85
MOL File: 135949-60-9.mol

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RB 101 Property

Boiling point:: 757.5±60.0 °C(Predicted)
Density: 1.210±0.06 g/cm3(Predicted)
pka: 13.85±0.46(Predicted)

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Hazard and Precautionary Statements (GHS)

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RB 101 Chemical Properties,Usage,Production

Uses

RB 101 is an active mixed inhibitor against two enzymes which metabolize the enkephalins neutral endopeptidase and aminopeptidase N. RB 101 has rather long-lasting antinociceptive effects. RB 101 inhibits the in vivo [3H]DPN binding both under basal conditions and after swim stress in mice. RB 101 can be used to determine the precise in vivo localization of enkephalinergic pathways recruited by various stimuli[1][2].

References

[1] Baamonde A, et al. Antidepressant-type effects of endogenous enkephalins protected by systemic RB 101 are mediated by opioid delta and dopamine D1 receptor stimulation. Eur J Pharmacol. 1992 Jun 5;216(2):157-66. DOI:10.1016/0014-2999(92)90356-9
[2] Ruiz-Gayo M, et al. In vivo occupation of mouse brain opioid receptors by endogenous enkephalins: blockade of enkephalin degrading enzymes by RB 101 inhibits [3H]diprenorphine binding. Brain Res. 1992 Feb 7;571(2):306-12. DOI:10.1016/0006-8993(92)90669-z

RB 101 Preparation Products And Raw materials

Raw materials

Preparation Products

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RB 101 Suppliers

China 3 United States 2 Global 5

Hangzhou Sage Chemical Co., Ltd.

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Shanghai HuanChuan Industry Co.,Ltd.

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TargetMol Chemicals Inc.

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TargetMol Chemicals Inc.

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TargetMol Chemicals Inc.

Tel: +17819995354
Email: marketing@targetmol.com
Country: United States
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135949-60-9, RB 101Related Search:

RB 101 DL-THIORPHAN N-(3-MERCAPTO-2-METHYLPROPANOYL)GLYCINE

RB 101

L-Phenylalanine, N-[2-[[[(2S)-2-aMino-4-(Methylthio)butyl]dithio]Methyl]-1-oxo-3-phenylpropyl]-,phenylMethyl ester

135949-60-9

C31H38N2O3S3