7-methoxyquinoline

Product Name: 7-methoxyquinoline
CAS No.: 4964-76-5
Chemical Name: 7-methoxyquinoline
Synonyms: 7-methoxyquinoline;Quinoline, 7-methoxy-
CBNumber: CB31356525
Molecular Formula: C10H9NO
Formula Weight: 159.18
MOL File: 4964-76-5.mol

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7-methoxyquinoline Property

Boiling point:: 143-145 °C(Press: 11 Torr)
Density: 1.130±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform
form: Oil
pka: 5.26±0.14(Predicted)
color: Yellow
InChI: InChI=1S/C10H9NO/c1-12-9-5-4-8-3-2-6-11-10(8)7-9/h2-7H,1H3
InChIKey: IVHJSNNMKJWPFW-UHFFFAOYSA-N
SMILES: N1C2C(=CC=C(OC)C=2)C=CC=1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: M267405
Product name: 7-Methoxyquinoline
Packaging: 100mg
Price: $105
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 11713
Product name: 7-Methoxyquinoline
Packaging: 25mg
Price: $860
Updated: 2021/12/16

AK Scientific

Product number: W6515
Product name: 7-Methoxyquinoline
Packaging: 25g
Price: $1224
Updated: 2021/12/16

Alichem

Product number: 4964765
Product name: 7-Methoxyquinoline
Packaging: 25g
Price: $1027.69
Updated: 2021/12/16

Crysdot

Product number: CD11116591
Product name: 7-Methoxyquinoline
Purity: 98%
Packaging: 5g
Price: $233
Updated: 2021/12/16

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7-methoxyquinoline Chemical Properties,Usage,Production

Chemical Properties

Yellow Oil

Uses

7-Methoxyquinoline (cas# 4964-76-5) is a compound useful in organic synthesis.

Synthesis

580-20-1

74-88-4

4964-76-5

General procedure for the synthesis of 7-methoxyquinoline from 7-hydroxyquinoline and iodomethane: 7-hydroxyquinoline (8 g, 55.11 mmol) was added to a solution of sodium hydride (5.5 g, 137.50 mmol, 60% pure) in N,N-dimethylformamide (150 mL). The reaction mixture was stirred in a water/ice bath at 0 °C for 1 hour. Subsequently, iodomethane (7.84 g, 55.23 mmol) was added and the reaction solution was continued to be stirred at room temperature for 1 hour. Upon completion of the reaction, the reaction was quenched by the addition of a water/ice mixture (700 mL) and extracted with ethyl acetate (3 x 200 mL). The organic layers were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure to give the crude product. The crude product was purified by silica gel column chromatography, using a petroleum ether solution of 6% ethyl acetate as eluent to give 7-methoxyquinoline as a red oil (5.5 g). The product was analyzed by LC-MS showing [M+H]+ peak of 160.0. 1H-NMR (300 MHz, CDCl3) data were as follows: δ 8.84-8.86 (m, 1H), 8.07-8.11 (m, 1H), 7.70-7.73 (t, J = 5.1 Hz, 1H), 7.44 (d, J = 2.4 Hz, 1H). 7.20-7.30 (m, 2H), 3.95 (s, 3H). Case No. BIOE0009-401-PC.

References

[1] Synthetic Communications, 2000, vol. 30, # 2, p. 367 - 375
[2] Patent: WO2012/94462, 2012, A2. Location in patent: Page/Page column 82
[3] Patent: WO2016/86200, 2016, A1. Location in patent: Page/Page column 278
[4] Patent: WO2012/58125, 2012, A1. Location in patent: Page/Page column 115; 116

7-methoxyquinoline Preparation Products And Raw materials

Raw materials

Preparation Products

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7-methoxyquinoline Suppliers

Canada 1 China 66 India 2 United States 6 Global 75

CHEMSWORTH

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Email: info@chemsworth.com
Country: India
ProdList: 6700
Advantage: 30

A.J Chemicals

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View Lastest Price from 7-methoxyquinoline manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 7-methoxyquinoline 4964-76-5
Price: US $1.00-100.00/KG
Min. Order: 1KG
Purity: 95%
Supply Ability: 300KG
Release date: 2024-08-16

Career Henan Chemical Co

Product: 7-methoxyquinoline 4964-76-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2020-01-09

4964-76-5, 7-methoxyquinolineRelated Search:

7-Methoxy-1H-indole 7-methoxyindoline-2,3-dione 7-METHOXY-ISOQUINOLINE ETHYL 8-CHLORO[1,3]DIOXOLO[4,5-G]QUINOLINE-7-CARBOXYLATE 4-HYDROXY-7-METHOXYQUINOLINE-3-CARBOXYLIC ACID 7-Methoxy-4-quinolinol Decoquinate 4-HYDROXY-7-METHOXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER buquinolate 7-METHOXY-2-METHYL-4-QUINOLINOL 4-HYDRAZINO-7-METHOXYQUINOLINE 8-HYDROXY-[1,3]DIOXOLO[4,5-G]QUINOLINE-7-CARBOXYLIC ACID ETHYL ESTER 7-ACETOXY-1-METHYLQUINOLINIUM IODIDE skimmianine 2-AMINO-7-METHOXY-3-PHENYLQUINOLINE 2,3-DIMETHOXY-11-PHENYLINDENO[3,2-B]QUINOLIN-10-ONE 2,4-DICHLORO-7-METHOXY-3-PHENYLQUINOLINE 7-METHOXY-3-NITROQUINOLINE

7-methoxyquinoline

Quinoline, 7-methoxy-

4964-76-5

Chemical Amines

Amines

Aromatics