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Zanamivir Amine

Product Name
Zanamivir Amine
CAS No.
130525-62-1
Chemical Name
Zanamivir Amine
Synonyms
Zanamivir Amine;4-AM-DANA;Zanamivir Impurity 2;Zanamivir EP Impurity C;Zanamivir intermediates A;Zanamivir intermediate DN-1;Zanamivir Impurity 3(Zanamivir EP Impurity C);4-amino-2-deoxy-2,3-didehydro-N-acetylneuraminic acid;4-a-Amino-N-acetyl-2-deoxy-2,3-didehydro-D-neuraminate;"4-α-Amino-N-acetyl-2-deoxy-2,3-didehydro-D-neuraminate"
CBNumber
CB31371117
Molecular Formula
C11H18N2O7
Formula Weight
290.27
MOL File
130525-62-1.mol
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Zanamivir Amine Property

Boiling point:
734.5±60.0 °C(Predicted)
Density 
1.53±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
Methanol (Slightly), Water (Slightly)
form 
Solid
pka
3.42±0.60(Predicted)
color 
White to Off-White
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
Z148005
Product name
ZanamivirAmine
Packaging
2mg
Price
$250
Updated
2021/12/16
Usbiological
Product number
022941
Product name
Zanamivir Amine
Packaging
1mg
Price
$425
Updated
2021/12/16
Chemenu
Product number
CM126703
Product name
(2R,3R,4S)-3-acetamido-4-amino-2-((1R,2R)-1,2,3-trihydroxypropyl)-3,4-dihydro-2H-pyran-6-carboxylicacid
Purity
97%
Packaging
5g
Price
$701
Updated
2021/12/16
Crysdot
Product number
CD00011078
Product name
4-AM-DANA
Purity
97%
Packaging
5g
Price
$750
Updated
2021/12/16
Chemenu
Product number
CM126703
Product name
(2R,3R,4S)-3-acetamido-4-amino-2-((1R,2R)-1,2,3-trihydroxypropyl)-3,4-dihydro-2H-pyran-6-carboxylicacid
Purity
97%
Packaging
1g
Price
$234
Updated
2021/12/16
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Zanamivir Amine Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

Zanamivir Amine is a synthetic precursor of Zanamivir. Relenza (zanamivir) is a medication used to treat and prevent influenza caused by influenza A and influenza B viruses.

Biological Activity

Zanamivir amine is a neuraminidase inhibitor with antiviral activity. Zanamivir amine can effectively inhibit the proliferation of influenza virus. Zanamivir amine is clinically used to inhibit influenza infection. Zanamivir amine reduces viral load by interfering with the viral replication process.

References

[1] DENNIS SCHADE . Zanamivir Amidoxime- and N-Hydroxyguanidine-Based Prodrug Approaches to Tackle Poor Oral Bioavailability[J]. Journal of pharmaceutical sciences, 2015, 104 9: Pages 3208-3219. DOI:10.1002/jps.24508.

Zanamivir Amine Preparation Products And Raw materials

Raw materials

Preparation Products

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Zanamivir Amine Suppliers

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J & K SCIENTIFIC LTD.
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View Lastest Price from Zanamivir Amine manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
4-a-Amino-N-acetyl-2-deoxy-2,3-didehydro-D-neuraminate 130525-62-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-26
Career Henan Chemical Co
Product
4-amino-2-deoxy-2,3-didehydro-N-acetylneuraminic acid 130525-62-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kgs
Release date
2020-02-19

130525-62-1, Zanamivir AmineRelated Search:

2-(Morpholinothio)benzothiazole Cyclopentyl 3-[2-Methoxy-4-(M-tolylsulfonylcarbaMoyl)benzyl]-1-Methylindol-5-ylcarbaMate Methyl 3-[2-Methoxy-4-(o-tolylsulfonylcarbaMoyl)benzyl]- Cyclopentyl 3-[2-Methoxy-4-(p-tolylsulfonylcarbaMoyl)benzyl]-1-Methylindol-5-ylcarbaMate Zanamivir Impurity 4 Zanamivir Impurity 5 Zanamivir Impurity 3 4-N-tert-Butyloxycarbonyl ZanaMivir AMine methyl (3aR,4R,7aR)-2-methyl-4-(1S,2R,3-triacetoxypropyl)-3a,7a-dihydro-4H-pyrano[3,4-d]oxazole-6-carboxylate 1H-Pyrazole-1-carboxamidine hydrochloride D-GLYCERO-D-GALACTO-NON-2-ENONIC ACID Zanamivir N-Cyano Zanamivir Amine Triacetate Methyl Ester Zanamivir Azide Methyl Ester ZANAMIVIR HYDRATE 3,4-Dihydro-2H-pyran

  • 4-a-Amino-N-acetyl-2-deoxy-2,3-didehydro-D-neuraminate
  • 4-amino-2-deoxy-2,3-didehydro-N-acetylneuraminic acid
  • (4S,5R,6R)-5-ACETAMIDO-4-AMINO-6-[(1R,2R)-1,2,3-TRIHYDROXYPROPYL]-5,6-DIHYDROPYRAN-2-CARBOXYLIC ACID
  • Zanamivir Amine
  • 4-AM-DANA
  • 5-(Acetylamino)-4-amino-2,6-anhydro-3,4,5-trideoxy-D-glycero-D-galactonon-2-enonic acid
  • Zanamivir intermediates A
  • Zanamivir EP Impurity C
  • Zanamivir intermediate DN-1
  • D-glycero-D-galacto-Non-2-enonic acid, 5-(acetylamino)-4-amino-2,6-anhydro-3,4,5-trideoxy-
  • Zanamivir Impurity 3(Zanamivir EP Impurity C)
  • Zanamivir Impurity 2
  • "4-α-Amino-N-acetyl-2-deoxy-2,3-didehydro-D-neuraminate"
  • 4-alpha-Amino-N-acetyl-2-deoxy-2,3-didehydro-D-neuraminate
  • 5-acetamido-4-amino-2,6-anhydro-3,4,5-trideoxy-D-glycero-D-galacto-non-2-enonic acid
  • 130525-62-1
  • Anti-virals
  • Intermediates & Fine Chemicals
  • Pharmaceuticals