ChemicalBook > CAS DataBase List > ONO EI-601
ONO EI-601
- Product Name
- ONO EI-601
- CAS No.
- 155023-59-9
- Chemical Name
- ONO EI-601
- Synonyms
- ONO EI-601;Severus Impurity 3;Sivelestat Impurity 2;Severlastat Impurity 2;Xiweilai Sitana Impurities;Sivelestat sodium Impurity 3;(2-((4-hydroxyphenyl)sulfonamido)benzoyl)glycine;N-(2-(p-Hydroxyphenylsulfonylamino)benzoyl)glycine;Glycine, N-[2-[[(4-hydroxyphenyl)sulfonyl]amino]benzoyl]-;2-[[4-(2,2-dimethylpropanoyloxy)phenyl]sulfonylamino]acetic acid
- CBNumber
- CB31383992
- Molecular Formula
- C15H14N2O6S
- Formula Weight
- 350.35
- MOL File
- 155023-59-9.mol
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ONO EI-601 Chemical Properties,Usage,Production
Description
Ono EI-601 is the main metabolite of the human neutrophil elastase inhibitor ONO-5046. In plasma and urine by direct injection column-switching HPLC proved to be useful for pharmacokinetic, toxicological and clinical studies.
Uses
ONO-EI-601 is the major metabolite of human neutrophil elastase inhibitor ONO-5046. ONO-5046 has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19[1].
References
[1] Shintani T, et al. Simultaneous determination of human neutrophil elastase inhibitor (ONO-5046) and its metabolite in plasma and urine by direct injection column-switching HPLC. J Pharm Biomed Anal. 1994 Mar;12(3):397-405. DOI:10.1016/0731-7085(94)90017-5
ONO EI-601 Preparation Products And Raw materials
Raw materials
Preparation Products
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155023-59-9, ONO EI-601Related Search:
Glycine, N-(2-aminobenzoyl)-, ethyl ester
Propanoic acid, 2,2-dimethyl-, 4-[[[2-[[(2-methoxy-2-oxoethyl)amino]carbonyl]phenyl]amino]sulfonyl]phenyl ester
4-CHLOROSULFONYLPHENYLPIVALATE
2-[[[4-(2,2-dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]-Benzoic acid
Sivelestat