2,4-DIAMINOANISOLE Property

Melting point:

67.5°C

Boiling point:

253.57°C (rough estimate)

Density 

1.1315 (rough estimate)

refractive index 

1.5200 (estimate)

solubility 

Chloroform (Slightly), DMSO (Slightly), Methanol (Very Slightly)

Colour Index 

76050

pka

5.19±0.10(Predicted)

BRN 

2085522

CAS DataBase Reference

615-05-4(CAS DataBase Reference)

NIST Chemistry Reference

1,3-Benzenediamine, 4-methoxy-(615-05-4)

IARC

2B (Vol. Sup 7, 79) 2001

EPA Substance Registry System

2,4-Diaminoanisole (615-05-4)

Safety

Hazard Codes 

T,N

Risk Statements 

45-22-51/53-68

Safety Statements 

53-45-61

RIDADR 

2811

WGK Germany 

3

RTECS 

BZ8580500

HazardClass 

6.1(b)

PackingGroup 

III

Hazardous Substances Data

615-05-4(Hazardous Substances Data)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H341Suspected of causing genetic defects

H350May cause cancer

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P273Avoid release to the environment.

P308+P313IF exposed or concerned: Get medical advice/attention.

2,4-DIAMINOANISOLE Chemical Properties,Usage,Production

Description

2,4-Diaminoanisole is a needle-like solid.Molecular weight = 138.19; Freezing/Melting point67-68℃. The sulfate is an off-white to violet powder.Hazard Identification (based on NFPA-704 M RatingSystem): Health 3, Flammability 0, Reactivity 0 (includessulfate). Soluble in water.

Chemical Properties

2,4-Diaminoanisole is a needle-like solid.

Uses

2,4-Diaminoanisole may be used as an analytical reference standard for the determination of the analyte in:

• Mainstream waterpipe smoke using liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS).
• Haircolor products by high performance liquid chromatography (HPLC).

Definition

ChEBI: 2,4-Diaminoanisole is a member of methoxybenzenes.

General Description

Colorless needles. Primarily used (along with salts such as 2,4-DIAMINOANISOLE sulfate) as a component of hair & fur dye formulations.

Reactivity Profile

2,4-DIAMINOANISOLE is incompatible with the following: Strong oxidizers .

Safety Profile

Confirmed carcinogen. Poison by intraperitoneal route. Moderately toxic by ingestion. Experimental reproductive effects. Human mutation data reported. A skin irritant. When heated to decomposition it emits toxic fumes of NOx. See also other diaminoanisole entries.

Potential Exposure

The principal use of 2,4-diamino-ani- sole (and its salts such as the sulfate) as a component of oxidation (permanent) hair and fur dye formulations. Human exposure to 2,4-diaminoanisole sulfate may possibly occur through skin absorption at chemical and dye production facilities, as well as through dermal contact in persons using hair dyes containing the chemical.

First aid

If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seekmedical attention immediately. If this chemical contactsthe skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove fromexposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing hasstopped and CPR if heart action has stopped. Transferpromptly to a medical facility. When this chemical hasbeen swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit.

storage

Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with 2,4-DAAsulfate you should be trained on its proper handling andstorage. A regulated, marked area should be establishedwhere this chemical is handled, used, or stored in compliance with OSHA Standard 1910.1045. Store in tightlyclosed containers in a cool, well-ventilated area away fromaluminum and magnesium.

Shipping

UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN3143 Dyes, solid, toxic, n.o.s. or Dye intermediates, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.

Incompatibilities

Incompatible with strong oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, and epoxides. The sulfate may react violently with aluminum and magnesium.

Waste Disposal

Dissolve or mix the material with a combustible solvent and burn in a chemical incinera- tor equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed .