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ADENOSINE 5'-TRIPHOSPHATE, PERIODATE OXIDIZED SODIUM SALT

Product Name
ADENOSINE 5'-TRIPHOSPHATE, PERIODATE OXIDIZED SODIUM SALT
CAS No.
71997-40-5
Chemical Name
ADENOSINE 5'-TRIPHOSPHATE, PERIODATE OXIDIZED SODIUM SALT
Synonyms
oATP;Oxidized ATP trisodium salt;adenosine 5'-triphosphate-2',3'-dialdehyde;Adenosine 5′-triphosphate, periodate oxidized;Oxidized ATP (oATP) - CAS 71997-40-5 - Calbiochem;ADENOSINE 5-TRIPHOSPHATE, PERIODATEOXIDI ZED SODIUM;ADENOSINE 5'-TRIPHOSPHATE-2', 3'-DIALDEHYDE SODIUM SALT;Adenosine 5`-triphosphate sodiuM salt periodate oxidized;ADENOSINE 5'-TRIPHOSPHATE, PERIODATE OXIDIZED SODIUM SALT
CBNumber
CB3141054
Molecular Formula
C10H13N5NaO13P3
Formula Weight
527.15
MOL File
71997-40-5.mol
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ADENOSINE 5'-TRIPHOSPHATE, PERIODATE OXIDIZED SODIUM SALT Property

storage temp. 
-20°C
form 
White powder
color 
White to off-white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A6779
Product name
Adenosine 5′-triphosphate, periodate oxidized sodium salt
Purity
≥97%
Packaging
25mg
Price
$236
Updated
2024/03/01
Sigma-Aldrich
Product number
A6779
Product name
Adenosine 5′-triphosphate, periodate oxidized sodium salt
Purity
≥97%
Packaging
100mg
Price
$777
Updated
2024/03/01
Sigma-Aldrich
Product number
5.05758
Product name
Oxidized ATP (oATP) - CAS 71997-40-5 - Calbiochem
Packaging
25mg
Price
$252
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
NUC0003769
Product name
ADENOSINE-5'-TRIPHOSPHATE PERIODATE OXIDIZED SODIUM SALT
Purity
95.00%
Packaging
0.5G
Price
$1478.4
Updated
2021/12/16
AHH
Product number
MT-46686
Product name
Adenosine 5′-triphosphate, periodate oxidized sodium salt
Purity
95%
Packaging
0.25g
Price
$380
Updated
2021/12/16
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ADENOSINE 5'-TRIPHOSPHATE, PERIODATE OXIDIZED SODIUM SALT Chemical Properties,Usage,Production

Uses

Adenosine 5′-triphosphate, periodate oxidized sodium salt has been used:

  • as an antagonist of the purinergic receptor, P2 × 7 to inhibit P2 × 7 pathway
  • as a nonspecific agonist to assess the activity of P2×7-R by the mobilization of Ca2+
  • to evaluate the physiological significance of elevated intracellular ATP levels
  • increased?P2rx7?expression for osteoclastogenesis in?Flcn-deficient cells

General Description

A 2′,3′-dialdehyde derivative of ATP that is commonly used to affinity label nucleotide sites in enzymes. Acts as a specific, irreversible antagonist of P2Z/P2X7 purinergic receptors in J774 mouse macrophages. Does not affect P2γ receptors. Inhibits inflammatory pain in arthritic rat model by blocking ATP action on P2X7 receptor in nerve terminals. Also shown to irreversibly block ATP-induced Ca2+ influx in lymphocytes (?100 μM). O-ATP-treated mice display better preservation and lower rate of rejection of pancreatic islet grafts with reduced Th1 transcripts.

Biochem/physiol Actions

Reversible: no

ADENOSINE 5'-TRIPHOSPHATE, PERIODATE OXIDIZED SODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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ADENOSINE 5'-TRIPHOSPHATE, PERIODATE OXIDIZED SODIUM SALT Suppliers

Tianjin heowns Biochemical Technology Co., Ltd.
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China
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Sigma-Aldrich
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51456
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TargetMol Chemicals Inc.
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Shanghai Guchen Biotechnology Co., LTD
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Yick-Vic Chemicals & Pharmaceuticals (HK) Ltd
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Guangzhou WeiBo Chemical Co., Ltd.
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Shanghai PI Chemicals Ltd.
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71997-40-5, ADENOSINE 5'-TRIPHOSPHATE, PERIODATE OXIDIZED SODIUM SALTRelated Search:


  • ADENOSINE 5'-TRIPHOSPHATE, PERIODATE OXIDIZED SODIUM SALT
  • ADENOSINE 5'-TRIPHOSPHATE-2', 3'-DIALDEHYDE SODIUM SALT
  • oATP
  • Adenosine 5′-triphosphate, periodate oxidized
  • ADENOSINE 5-TRIPHOSPHATE, PERIODATEOXIDI ZED SODIUM
  • adenosine 5'-triphosphate-2',3'-dialdehyde
  • Adenosine 5`-triphosphate sodiuM salt periodate oxidized
  • Oxidized ATP (oATP) - CAS 71997-40-5 - Calbiochem
  • Oxidized ATP trisodium salt
  • 71997-40-5
  • C10H14N5O13P3
  • C10H13N5NaO13P3
  • Nucleotides
  • Nucleosides, Nucleotides, Oligonucleotides
  • Biochemicals and Reagents
  • BioChemical