ALPHA-AMANITIN

Product Name: ALPHA-AMANITIN
CAS No.: 23109-05-9
Chemical Name: ALPHA-AMANITIN
Synonyms: Α-AMANITIN;α-Amanitin;A-AMANITIN;Aids004473;α-Amatoxin;Aids-004473;AMANITIN, A-;ALPHA-AMANTIN;ALPHA-AMANITIN;alpha-amatoxin
CBNumber: CB3142945
Molecular Formula: C39H54N10O14S
Formula Weight: 918.98
MOL File: 23109-05-9.mol

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ALPHA-AMANITIN Property

Melting point:: 254-255 °C(lit.)
alpha: D20 +191°
Boiling point:: 1622.2±65.0 °C(Predicted)
Density: 1.1626 (rough estimate)
refractive index: 1.7400 (estimate)
storage temp.: −20°C
solubility: H₂O: 1.0 mg/mL
form: powder
pka: 9.63±0.70(Predicted)
color: white to light yellow
optical activity: +19120 (H2O)
Water Solubility: Soluble to 5 mM in ethanol and to 5 mM in water
Merck: 13,370
BRN: 1071138
InChIKey: CIORWBWIBBPXCG-PWKRRBCNNA-N

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Safety

Hazard Codes: T+
Risk Statements: 26/27/28-33-26/28
Safety Statements: 36/37/39-45-36/37-28
RIDADR: UN 3462 6.1/PG 2
WGK Germany: 3
RTECS: BD6195000
F: 8-10-18-21
HazardClass: 6.1(a)
PackingGroup: I
HS Code: 2934999090
Hazardous Substances Data: 23109-05-9(Hazardous Substances Data)
Toxicity: LD50 i.p. in albino mice: 0.1 mg/kg (Wieland, Wieland)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H300Fatal if swallowed

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P314Get medical advice/attention if you feel unwell.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A2263
Product name: α-Amanitin
Purity: from Amanita phalloides, ≥90% (HPLC), powder
Packaging: 1mg
Price: $340
Updated: 2024/03/01

Cayman Chemical

Product number: 17898
Product name: α-Amanitin
Purity: ≥90%
Packaging: 1mg
Price: $227
Updated: 2024/03/01

Tocris

Product number: 4025
Product name: alpha-Amanitin
Purity: ≥95%(HPLC)
Packaging: 1
Price: $291
Updated: 2021/12/16

Usbiological

Product number: 257178
Product name: α-Amanitin
Packaging: 1mg
Price: $588
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA57619
Product name: a-Amanitin
Packaging: 5mg
Price: $800
Updated: 2021/12/16

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ALPHA-AMANITIN Chemical Properties,Usage,Production

Uses

α-Amanitin has been used:

for inducing transcriptional arrest in NT2 cells prior to immunofluorescence assay
to induce nephrotoxicity in mice renal tissues
to induce and analyse genotoxicity in mice bone marrow cells by cell viability assay, comet assay and chromosomal aberration assay

Biological Activity

α-amanitin, the most deleterious toxin of a. phalloides to humans, inhibits rna polymerase ii (rnapii), causing hepatic and renal failure.

Biochem/physiol Actions

The major toxic constituent of the mushroom, Amanita phalloides, inhibits eukaryotic RNA polymerase II and III, but does not inhibit RNA polymerase I or bacterial RNA polymerase. Inhibits mammalian protein synthesis.

storage

Store at -20°C

ALPHA-AMANITIN Preparation Products And Raw materials

Raw materials

Preparation Products

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ALPHA-AMANITIN Suppliers

China 71 Europe 2 Germany 4 India 1 Japan 2 Switzerland 3 United Kingdom 10 United States 15 Global 108

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 14055
Advantage: 65

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12335
Advantage: 58

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9891
Advantage: 58

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

ShenZhen InnoSyn Biotech Co.,Ltd

Tel: 0755-28351685 18503098468
Fax: +86-755-28466854
Email: innosyn@163.com
Country: China
ProdList: 600
Advantage: 55

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

Nanjing Sunlida Biological Technology Co., Ltd.

Tel: 025-57798810
Fax: 025-57019371
Email: sales@sunlidabio.com
Country: China
ProdList: 3239
Advantage: 55

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3466
Advantage: 58

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View Lastest Price from ALPHA-AMANITIN manufacturers

Wuhan Boyuan Import & Export Co., LTD

Product: α-Amanitin 23109-05-9
Price: US $60.00-45.00/mg
Min. Order: 1mg
Purity: 99.96%
Supply Ability: 1kg
Release date: 2023-03-14

Hebei Kangcang new material Technology Co., LTD

Product: alpha-Amanitin 23109-05-9
Price: US $9.00-70.00/g
Min. Order: 10g
Purity: 99%
Supply Ability: 10 tons
Release date: 2024-03-27

Hebei Fengqiang Trading Co., LTD

Product: α-Amanitin 23109-05-9
Price: US $100.00/drum
Min. Order: 1drum
Purity: 99
Supply Ability: 5000
Release date: 2023-09-05

23109-05-9, ALPHA-AMANITINRelated Search:

gamma-amanitin ALPHA-AMANITIN OLEATE alpha-Amanitin, 1-l-aspartic acid- METHYL ALPHA-AMANITIN OLEATE 6'-O-methyl alpha-amanitin 4,9-dioxo-5,10-diazatetradecane ALPHA-AMANITIN

Aids004473

Aids-004473

AMANITIN, a-(RG)

AMANITIN, a-(RG)(CALL)

cyclo[L-Asparaginyl-4-hydroxy-L-proly-(R-4,5-dihydroxy-L-isoleucyl-6-hydroxy-2-mercapto-L-tryptophylglycyl-L-isoleucylglycyl-L-cysteinyl]cyclic(4-8)-sulfide(R)-S-oxide

alpha-AMantine, froM AManita Phalloides

Α-AMANITIN

AMANITIN, A-

ALPHA-AMANITIN

ALPHA-AMANITIN, AMANITA SPECIES

ALPHA-AMANITINE

A-AMANITIN

Cyclo[L-Asn-L-t4Hyp-[(3R,4R)-4,5-dihydroxy-3-methyl-L-Nva-]-6-hydroxy-L-Trp2(1)-Gly-3-methyl-L-Nva-Gly-3-oxomercapto(1)-L-Ala-]

alpha-amatoxin

cyclic(l-asparaginyl-4-hydroxy-l-prolyl-(r)-4,5-dihydroxy-l-isoleucyl-6-hydrox

ulfide,(r)-s-oxide

y-2-mercapto-l-tryptophylglycyl-l-isoleucylglycyl-l-cysteinyl),cyclic(4-8)-s

ALPHA-AMANITIN FROM AMANITA PHALLOIDES

A-AMANITIN FROM AMANITA PHALLOIDES

ALPHA-AMANTIN

ALPHA-AMANTINE

A-AMANTINE, FROM AMANITA PHALLOIDES

alpha-Amanitine, from Amanita Phalloides

Α-AMANITIN;Α-AMATOXIN

alpha-Amanitin (α-Amanitin

α-Amanitin DISCONTINUED

α-Amanitin, from Amanita Phalloides

α-Amanitin

α-Amatoxin

*Chlorobutanol Impurity?1 (Chlorobutanol EP Impurity?A)(Chloroform)

23109-05-9

C39H54N10O14S

BioChemical

Biochemicals and Reagents

Cell Biology

Cell Signaling and Neuroscience

Gene Regulation and Expression

Enzymes, Inhibitors, and Substrates

Enzyme Inhibitors by Type

Enzyme Inhibitors

DNA-RNA Transcription Regulators

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Alkaloids

DNA-RNA Transcription RegulatorsCell Signaling and Neuroscience

Gene Regulation and Expression

Cell Signaling and Neuroscience

Mushroom

Toxins and Venoms

Enzyme Inhibitors

Enzyme Inhibitors by Type

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Miscellaneous Enzyme

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