ANTI-CALPASTATIN
- Product Name
- ANTI-CALPASTATIN
- Chemical Name
- ANTI-CALPASTATIN
- Synonyms
- Anti-BS-17;Anti-MGC9402;ANTI-CALPASTATIN;Anti-Calpain inhibitor;ANTI-CALPASTATIN, HUMAN;ANTI-CALPASTATIN MOUSE MAB;Anti-Calpastatin isoform a;ANTI-CALPASTATIN (DOMAIN IV);ANTI-CALPASTATIN (DOMAIN II);ANTI-CALPASTATIN, HUMAN (MOUSE)
- CBNumber
- CB3143962
- Formula Weight
- 0
- MOL File
- Mol file
ANTI-CALPASTATIN Property
- storage temp.
- −20°C
- form
- buffered aqueous solution
- biological source
- mouse
Safety
- WGK Germany
- -
- Storage Class
- 10 - Combustible liquids
N-Bromosuccinimide Price
- Product number
- C270
- Product name
- Monoclonal Anti-Calpastatin antibody produced in mouse
- Purity
- clone 1F7E3D10, ascites fluid, buffered aqueous solution
- Packaging
- 100μL
- Price
- $599
- Updated
- 2025/07/31
- Product number
- ATB0010642
- Product name
- ANTI-CALPASTATIN
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.36
- Updated
- 2021/12/16
ANTI-CALPASTATIN Chemical Properties,Usage,Production
Uses
Monoclonal Anti-Calpastatin antibody produced in mouse is suitable for indirect immunofluorescence at a dilution of 1:200 and for western blotting at a dilution of 1:5,000.
General Description
Calpastatin is a protein encoded by the CAST gene in humans. Calpastatin is an endogenous inhibitor of the ubiquitous calcium dependent proteinases μ- and m-calpain. It plays a key role in many cellular physiological and pathological processes. Calpastatin level is very important for controlling calpain activity.
Biochem/physiol Actions
Calpastatin availability in cytosol is controlled by Ca2+ and cyclic AMP. Prolonged calpain activation promotes degradation of calpastatin. Calpastatin is found to be overexpressed in mycoplasma-contaminated cultured cells. CAST gene is found to be involved in genetic susceptibility to Keratoconus (KC), a genetically heterogeneous corneal dystrophy. It is also found to be associated with Parkinson′s disease (PD) and single nucleotide polymorphisms (SNPs).
ANTI-CALPASTATIN Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-CALPASTATIN Suppliers
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