ChemicalBook > CAS DataBase List > 4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane

4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane

Product Name
4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane
CAS No.
57280-22-5
Chemical Name
4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane
Synonyms
0]Octane;4-Dimethyl-3;8-trioxabic-yclo[5;Trioxabicyclooctane;4,4-dimethyl-3,5,8-;Gadobutrol Impurity 49;2-Ethoxyethyl ether 112-36-7;4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.]octane;4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane;3,5,8-Trioxabicyclo[5.1.0]octane, 4,4-diMethyl-
CBNumber
CB31452526
Molecular Formula
C7H12O3
Formula Weight
144.17
MOL File
57280-22-5.mol
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4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane Property

Boiling point:
179℃
Density 
1.071
refractive index 
1.4560 to 1.4600
Flash point:
56℃
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
clear liquid
color 
Colorless to Light yellow to Light orange
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Safety

Hazard Codes 
Xi
Risk Statements 
36-43
Safety Statements 
26-36/37-24/25
HS Code 
29329990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical
Product number
D5200
Product name
4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane
Purity
>95.0%(GC)
Packaging
1g
Price
$30
Updated
2024/03/01
TCI Chemical
Product number
D5200
Product name
4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane
Purity
>95.0%(GC)
Packaging
5g
Price
$108
Updated
2024/03/01
TRC
Product number
D480778
Product name
4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane
Packaging
25g
Price
$165
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD29424
Product name
4,4-Dimethyl-3,5,8-trioxabicyclo[5,1,0]octane
Packaging
25g
Price
$125
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD29424
Product name
4,4-Dimethyl-3,5,8-trioxabicyclo[5,1,0]octane
Packaging
50g
Price
$200
Updated
2021/12/16
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4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane Chemical Properties,Usage,Production

Chemical Properties

Clear colorless to yellow liquid

Uses

4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane is used in the CO2-mediated formation of chiral carbamates from meso-epoxides via polycarbonate intermediates and amine nucleophiles, which opens up a wide a wide range of CO2-based carbamate scaffolds with excellent yields and 99% enantiomeric excess.

Application

4, 4-dimethyl-3,5, 8-trioxane [5,1,0] octane is a key intermediate in the preparation of gadobinol. As a meso epoxide, it could be used to obtain optically pure ABT derivatives through Ti(IV)/BINOL catalyzed asymmetric aminolysis[1].

References

[1] Bao H, et al. Insight into the Mechanism of the Asymmetric Ring-Opening Aminolysis of 4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane Catalyzed by Titanium/BINOLate/Water System: Evidence for the Ti(BINOLate)2-Bearing Active Catalyst Entities and the Role of Water. Journal of the American Chemical Society, 2008; 130: 10116–10127.

4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane Preparation Products And Raw materials

Raw materials

Preparation Products

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4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane Suppliers

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View Lastest Price from 4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane manufacturers

Hangzhou ICH Biofarm Co., Ltd
Product
4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane 57280-22-5
Price
US $0.00-0.00/kg
Min. Order
0.10000000149011612kg
Purity
98.0%min
Supply Ability
9000kg
Release date
2024-09-14
Henan Fengda Chemical Co., Ltd
Product
4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane 57280-22-5
Price
US $30.00-0.80/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-26
Changzhou Rokechem Technology Co., Ltd.
Product
4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]octane 57280-22-5
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
≥98%
Supply Ability
1-1000KGS
Release date
2022-11-14

57280-22-5, 4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]OctaneRelated Search:


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