4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane

Product Name: 4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane
CAS No.: 57280-22-5
Chemical Name: 4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane
Synonyms: 0]Octane;4-Dimethyl-3;8-trioxabic-yclo[5;Trioxabicyclooctane;4,4-dimethyl-3,5,8-;Gadobutrol Impurity 49;2-Ethoxyethyl ether 112-36-7;4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.]octane;4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane;3,5,8-Trioxabicyclo[5.1.0]octane, 4,4-diMethyl-
CBNumber: CB31452526
Molecular Formula: C7H12O3
Formula Weight: 144.17
MOL File: 57280-22-5.mol

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4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane Property

Boiling point:: 179℃
Density: 1.071
refractive index: 1.4560 to 1.4600
Flash point:: 56℃
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: clear liquid
color: Colorless to Light yellow to Light orange

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Safety

Hazard Codes: Xi
Risk Statements: 36-43
Safety Statements: 26-36/37-24/25
HS Code: 29329990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical

Product number: D5200
Product name: 4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane
Purity: >95.0%(GC)
Packaging: 1g
Price: $30
Updated: 2024/03/01

TCI Chemical

Product number: D5200
Product name: 4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane
Purity: >95.0%(GC)
Packaging: 5g
Price: $108
Updated: 2024/03/01

TRC

Product number: D480778
Product name: 4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane
Packaging: 25g
Price: $165
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD29424
Product name: 4,4-Dimethyl-3,5,8-trioxabicyclo[5,1,0]octane
Packaging: 25g
Price: $125
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD29424
Product name: 4,4-Dimethyl-3,5,8-trioxabicyclo[5,1,0]octane
Packaging: 50g
Price: $200
Updated: 2021/12/16

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4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane Chemical Properties,Usage,Production

Chemical Properties

Clear colorless to yellow liquid

Uses

4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane is used in the CO2-mediated formation of chiral carbamates from meso-epoxides via polycarbonate intermediates and amine nucleophiles, which opens up a wide a wide range of CO2-based carbamate scaffolds with excellent yields and 99% enantiomeric excess.

Application

4, 4-dimethyl-3,5, 8-trioxane [5,1,0] octane is a key intermediate in the preparation of gadobinol. As a meso epoxide, it could be used to obtain optically pure ABT derivatives through Ti(IV)/BINOL catalyzed asymmetric aminolysis[1].

References

[1] Bao H, et al. Insight into the Mechanism of the Asymmetric Ring-Opening Aminolysis of 4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane Catalyzed by Titanium/BINOLate/Water System: Evidence for the Ti(BINOLate)2-Bearing Active Catalyst Entities and the Role of Water. Journal of the American Chemical Society, 2008; 130: 10116–10127.

4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane Preparation Products And Raw materials

Raw materials

Preparation Products

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4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane Suppliers

Americas 1 China 231 Europe 1 France 1 India 10 Japan 1 South Korea 1 Switzerland 1 United Kingdom 4 United States 9 Global 260

Matrix Fine Chemicals GmbH

Tel: --
Fax: --
Email: nfo@matrix-fine-chemicals.com
Country: Switzerland
ProdList: 6968
Advantage: 58

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View Lastest Price from 4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane manufacturers

Hangzhou ICH Biofarm Co., Ltd

Product: 4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane 57280-22-5
Price: US $0.00-0.00/kg
Min. Order: 0.10000000149011612kg
Purity: 98.0%min
Supply Ability: 9000kg
Release date: 2024-09-14

Henan Fengda Chemical Co., Ltd

Product: 4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane 57280-22-5
Price: US $30.00-0.80/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-03-26

Changzhou Rokechem Technology Co., Ltd.

Product: 4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]octane 57280-22-5
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: ≥98%
Supply Ability: 1-1000KGS
Release date: 2022-11-14

57280-22-5, 4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]OctaneRelated Search:

4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane

3,5,8-Trioxabicyclo[5.1.0]octane, 4,4-diMethyl-

4,4-diMethyl-3,5,8-trioxabicyclo[5.1.0]octane(EP2)

4,4-Dimethyl-3,5,8-trioxabic-yclo[5.1.0]octane(DTC-octane)

Gadobutrol Impurity 49

4 4-DIMETHYL-3 5 8-TRIOXABICYCLO (5.1.0)OCTANE TOBO

0]Octane

4-Dimethyl-3

8-trioxabic-yclo[5

4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.]octane

China biggest manufacturer 4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane 57280-22-5

2-Ethoxyethyl ether 112-36-7

3,5,8-Trioxabicyclo[5.1.0]octane, 4,4-dimethyl- 4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane

Trioxabicyclooctane

4,4-dimethyl-3,5,8-

57280-22-5

572780-22-5

57280-22-5