2-AMINO-(4'-NITRO)ACETOPHENONE HYDROCHLORIDE
- Product Name
- 2-AMINO-(4'-NITRO)ACETOPHENONE HYDROCHLORIDE
- CAS No.
- 5425-81-0
- Chemical Name
- 2-AMINO-(4'-NITRO)ACETOPHENONE HYDROCHLORIDE
- Synonyms
- AURORA 23208;OTAVA-BB BB7110952478;2-AMino-4'-nitroacetophenone HCl;2-AMino-p-nitro-acetophenone HCl;2-AMINO-P-NITRO-ACETOPHENONE HYDROCHLORIDE;2-AMINO-(4'-NITRO)ACETOPHENONE HYDROCHLORIDE;2-AMINO-1-(4-NITRO-PHENYL)-ETHANONE HYDROCHLORIDE;2-Amino-1-(4-nitrophenyl)ethanone hydrochloride (1:1);Ethanone, 2-amino-1-(4-nitrophenyl)-, hydrochloride (1:1);2-Amino-(4′-nitro)acetophenone hydrochloride, CAS 5425-81-0
- CBNumber
- CB3146488
- Molecular Formula
- C8H9ClN2O3
- Formula Weight
- 216.62
- MOL File
- 5425-81-0.mol
2-AMINO-(4'-NITRO)ACETOPHENONE HYDROCHLORIDE Property
- Melting point:
- >211°C (dec)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- color
- White to Off-White
- CAS DataBase Reference
- 5425-81-0(CAS DataBase Reference)
N-Bromosuccinimide Price
- Product number
- PH011994
- Product name
- 2-amino-1-(4-nitrophenyl)ethanone hydrochloride
- Purity
- AldrichCPR
- Packaging
- 100mg
- Price
- $134
- Updated
- 2023/06/20
- Product number
- A578998
- Product name
- 2-amino-1-(4-nitrophenyl)ethanone hydrochloride
- Packaging
- 50mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- A578998
- Product name
- 2-amino-1-(4-nitrophenyl)ethanone hydrochloride
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- A578998
- Product name
- 2-amino-1-(4-nitrophenyl)ethanone hydrochloride
- Packaging
- 500mg
- Price
- $245
- Updated
- 2021/12/16
- Product number
- 4654-5-59
- Product name
- 4-Nitrophenacylamine hydrochloride hydrate
- Packaging
- 250mg
- Price
- $84
- Updated
- 2021/12/16
2-AMINO-(4'-NITRO)ACETOPHENONE HYDROCHLORIDE Chemical Properties,Usage,Production
Synthesis
99-81-0
5425-81-0
Example 2: Synthesis of 2-amino-1-(4-nitrophenyl)ethanone hydrochloride 2-Bromo-4'-nitroacetophenone (25 g) prepared in Example 1 was dissolved in dichloromethane (250 mL), hexamethylenetetramine (20.1 g) was added, and the reaction was stirred for 1 hour at room temperature. After the reaction was completed, the solid crude product (30 g) was collected by filtration. The crude product was dissolved in a mixture of ethanol (162 mL) and concentrated hydrochloric acid (40 mL) and the reaction was continued with stirring for about 3 hours. After the reaction mixture was left to stand for about 48 hours, the solid product was precipitated, filtered, washed with water and dried to give the target compound 2-amino-1-(4-nitrophenyl)ethanone hydrochloride (refer to the method described in US4812470). Yield: 11.8 g (72% yield); 1H NMR (DMSO-d6, 300MHz): δ 8.3 (broad peak, 3H), 8.38 (double peak, 2H), 8.27 (double peak, 2H), 4.68 (single peak, 2H).
References
[1] Patent: WO2011/55289, 2011, A2. Location in patent: Page/Page column 36
[2] Patent: WO2012/29032, 2012, A2. Location in patent: Example 2
[3] European Journal of Medicinal Chemistry, 2012, vol. 54, p. 324 - 342
[4] European Journal of Medicinal Chemistry, 2014, vol. 79, p. 203 - 215
[5] Journal of Medicinal Chemistry, 1982, vol. 25, # 9, p. 1045 - 1050
2-AMINO-(4'-NITRO)ACETOPHENONE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
2-AMINO-(4'-NITRO)ACETOPHENONE HYDROCHLORIDE Suppliers
- Tel
- --
- Fax
- --
- north.america@otavachemicals.com
- Country
- Ukraine
- ProdList
- 6495
- Advantage
- 72
View Lastest Price from 2-AMINO-(4'-NITRO)ACETOPHENONE HYDROCHLORIDE manufacturers
- Product
- 2-amino-(4'-nitro)acetophenone hydrochloride 5425-81-0
- Price
- US $1.10-9.90/KG
- Min. Order
- 1KG
- Purity
- 99% min
- Supply Ability
- 100kg
- Release date
- 2025-08-18