BITHIONOL SULFOXIDE
- Product Name
- BITHIONOL SULFOXIDE
- CAS No.
- 844-26-8
- Chemical Name
- BITHIONOL SULFOXIDE
- Synonyms
- bitins;sulphene;distobitin;disto-5-cogla;Bithionoloxide;BITHIONOL SULFOXIDE;LABOTEST-BB LT00772303;Bithionol sulfoxidewith;2,2’-sulfinylbis(4,6-dichloro-pheno;6,6’-sulfinylbis(2,4-dichlorophenol)
- CBNumber
- CB3148053
- Molecular Formula
- C12H6Cl4O3S
- Formula Weight
- 372.05
- MOL File
- 844-26-8.mol
BITHIONOL SULFOXIDE Property
- Melting point:
- 220 °C(Solv: methanol (67-56-1))
- Boiling point:
- 532.7±50.0 °C(Predicted)
- Density
- 1.86±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: ≥ 250 mg/mL (671.95 mM)
- form
- Solid
- pka
- 4.79±0.48(Predicted)
- color
- White to off-white
Safety
- WGK Germany
- 3
- RTECS
- SM8800000
N-Bromosuccinimide Price
- Product number
- R579696
- Product name
- 6,6'-SULFINYLBIS(2,4-DICHLOROPHENOL)
- Purity
- Aldrich<sup>CPR</sup>
- Packaging
- 1 unit
- Price
- $113
- Updated
- 2025/07/31
- Product number
- R579696
- Product name
- 6,6'-SULFINYLBIS(2,4-DICHLOROPHENOL)
- Purity
- AldrichCPR
- Packaging
- 50mg
- Price
- $110
- Updated
- 2024/03/01
- Product number
- 263658
- Product name
- Bithionol sulfoxide
- Packaging
- 2g
- Price
- $333
- Updated
- 2021/12/16
- Product number
- 3493AH
- Product name
- Bithionolsulfoxide
- Packaging
- 10g
- Price
- $347
- Updated
- 2021/12/16
- Product number
- FB30271
- Product name
- Bithionol sulfoxide
- Packaging
- 25g
- Price
- $350
- Updated
- 2021/12/16
BITHIONOL SULFOXIDE Chemical Properties,Usage,Production
Uses
Bithionol sulfoxide is an anti-infection agent for parasites. Bithionol sulfoxide has mutagenic activity. Bithionol sulfoxide can be used in the research of parasite infection, such as paragonimiasis, flukes andcestodes infection[1][2][5].
in vivo
Bithionol sulfoxide (oral administration) shows LD50 values of 1000-5000 mg/kg (mice) and about 5000 mg/kg (rats), and increased serum AST at high doses (5000-100 mg/kg)[3].
Bithionol sulfoxide (80 and 90 mg/kg, oral administration) is effective against natural rumen fluke infections in dairy cattle[4].
| Animal Model: | Dairy cattle[4] |
| Dosage: | 60, 80 90 mg/kg |
| Administration: | Oral administration |
| Result: | Showed approximately 70% effective against rumen flukes infection at dosages of 80 and 90 mg/kg after one week post treatment. |
IC 50
Schistosome
References
[1] Florent RL, et al. In vitro toxicity of bithionol and bithionol sulphoxide to Neoparamoeba spp., the causative agent of amoebic gill disease (AGD). Dis Aquat Organ. 2010 Sep 17;91(3):257-62. DOI:10.3354/dao02269
[2] S P Yang, et al. Treatment of paragonimiasis with bithionol and bithionol sulfoxide. Dis Chest. 1967 Aug;52(2):220-32. DOI:10.1378/chest.52.2.220
[3] Lavri? A, et al. Oral toxicity of bithionol sulfoxide in mice and rats. Zbornik Veterinarske Fakultete Univerza Ljubljana 1990 Vol.27 No.1 pp.33-39 ref.22.
[4] Chompoochan T, et al. The anthelmintic effects of bithionol sulfoxide against sheep experimentally infected with Fasciola gigantica[C]//ACIAR PROCEEDINGS. 1996: 189-194.
[5] D.Mourot, et al. Mutagenicity of bithionol sulfoxide and its metabolites in the Salmonella/mammalian microsome test. Mutation Research/Genetic Toxicology, 1987, 188(1): 53-55.
BITHIONOL SULFOXIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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