4-CHLORO-6,7-DIFLUOROQUINAZOLINE
- Product Name
- 4-CHLORO-6,7-DIFLUOROQUINAZOLINE
- CAS No.
- 625080-60-6
- Chemical Name
- 4-CHLORO-6,7-DIFLUOROQUINAZOLINE
- Synonyms
- Quinazoline, 4-chloro-6,7-difluoro-
- CBNumber
- CB31502085
- Molecular Formula
- C8H3ClF2N2
- Formula Weight
- 200.57
- MOL File
- 625080-60-6.mol
4-CHLORO-6,7-DIFLUOROQUINAZOLINE Property
- Boiling point:
- 290.9±35.0 °C(Predicted)
- Density
- 1.538±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -0.04±0.70(Predicted)
- Appearance
- White to light yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 073182
- Product name
- 4-Chloro-6,7-difluoroquinazoline
- Purity
- 95+%
- Packaging
- 500mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- 073182
- Product name
- 4-Chloro-6,7-difluoroquinazoline
- Purity
- 95+%
- Packaging
- 1g
- Price
- $218
- Updated
- 2021/12/16
- Product number
- W7460
- Product name
- 4-Chloro-6,7-difluoroquinazoline
- Packaging
- 500mg
- Price
- $252
- Updated
- 2021/12/16
- Product number
- HCH0104835
- Product name
- 4-CHLORO-6,7-DIFLUOROQUINAZOLINE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $327.6
- Updated
- 2021/12/16
- Product number
- 073182
- Product name
- 4-Chloro-6,7-difluoroquinazoline
- Purity
- 95+%
- Packaging
- 5g
- Price
- $640
- Updated
- 2021/12/16
4-CHLORO-6,7-DIFLUOROQUINAZOLINE Chemical Properties,Usage,Production
Synthesis
205259-37-6
625080-60-6
Example 4A Step 2: 6,7-difluoro-4-hydroxyquinazoline (910 mg, 5 mmol) was added to trichlorophos (15 mL) followed by triethylamine (700 μL, 5 mmol). The reaction mixture was heated to reflux at 100 °C for 4 h. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure. The resulting solid was ground with ethyl acetate (2 × 100 mL), and the combined organic phases were rapidly filtered through a silica gel column to afford 4-chloro-6,7-difluoroquinazoline (870 mg, 4.35 mmol, 87% yield). m/z 201 ([M + H]+) by LC-MS (ESI).
References
[1] Patent: WO2009/117080, 2009, A1. Location in patent: Page/Page column 165
[2] Patent: US2006/281772, 2006, A1. Location in patent: Page/Page column 131
4-CHLORO-6,7-DIFLUOROQUINAZOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
4-CHLORO-6,7-DIFLUOROQUINAZOLINE Suppliers
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
- 58