4-CHLORO-5-IODO-6-METHYLPYRIMIDINE
- Product Name
- 4-CHLORO-5-IODO-6-METHYLPYRIMIDINE
- CAS No.
- 83410-15-5
- Chemical Name
- 4-CHLORO-5-IODO-6-METHYLPYRIMIDINE
- Synonyms
- 4-CHLORO-5-IODO-6-METHYLPYRIMIDINE;Pyrimidine, 4-chloro-5-iodo-6-methyl-
- CBNumber
- CB31502131
- Molecular Formula
- C5H4ClIN2
- Formula Weight
- 254.46
- MOL File
- 83410-15-5.mol
4-CHLORO-5-IODO-6-METHYLPYRIMIDINE Property
- storage temp.
- Keep in dark place,Sealed in dry,Store in freezer, under -20°C
- Appearance
- White to yellow Solid
N-Bromosuccinimide Price
- Product number
- FC140764
- Product name
- 4-Chloro-5-iodo-6-methylpyrimidine
- Packaging
- 50mg
- Price
- $56
- Updated
- 2021/12/16
- Product number
- FC140764
- Product name
- 4-Chloro-5-iodo-6-methylpyrimidine
- Packaging
- 100mg
- Price
- $98
- Updated
- 2021/12/16
- Product number
- Z5165
- Product name
- 4-Chloro-5-iodo-6-methylpyrimidine
- Packaging
- 50mg
- Price
- $125
- Updated
- 2021/12/16
- Product number
- HCH0358903
- Product name
- 4-CHLORO-5-IODO-6-METHYLPYRIMIDINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $498.14
- Updated
- 2021/12/16
- Product number
- FC140764
- Product name
- 4-Chloro-5-iodo-6-methylpyrimidine
- Packaging
- 500mg
- Price
- $340
- Updated
- 2021/12/16
4-CHLORO-5-IODO-6-METHYLPYRIMIDINE Chemical Properties,Usage,Production
Synthesis
7752-74-1
83410-15-5
General procedure for the synthesis of 4-chloro-5-iodo-6-methylpyrimidine from 5-iodo-6-methylpyrimidin-4(1H)-one: trichlorophosphorus oxychloride (POCl3, 5.3 mL, 0.057 mol) was added to a suspension of 5-iodo-6-methylpyrimidin-4(1H)-one (3.4 g, 0.0144 mol) in diethylene glycol dimethyl ether (60 mL), the reaction The mixture was stirred at 90 °C for 2 hours. After completion of the reaction, it was cooled to room temperature and the reaction mixture was slowly poured into a 10% aqueous solution of potassium carbonate (K2CO3, 200 mL) and stirring was continued for 1 hour. The resulting solid product was collected by filtration, washed with water and dried to afford 4-chloro-5-iodo-6-methylpyrimidine (2.9 g, 79% yield).
References
[1] Patent: WO2011/92197, 2011, A1. Location in patent: Page/Page column 22
[2] Patent: US2012/28958, 2012, A1. Location in patent: Page/Page column 8
[3] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 11, p. 3090 - 3104
4-CHLORO-5-IODO-6-METHYLPYRIMIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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