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benzo[d]oxazole-6-carboxylic acid

Product Name
benzo[d]oxazole-6-carboxylic acid
CAS No.
154235-77-5
Chemical Name
benzo[d]oxazole-6-carboxylic acid
Synonyms
SB9;Serpin B9-IN-1;6-Benzoxazolecarboxylic acid;Benzoxazole-6-carboxylic Acid;1,3-Benzoxazole-6-carboxylic acid;benzo[d]oxazole-6-carboxylic acid;1,3-Benzoxazole-6-carboxylic acid 97%;1,3-Benzoxazole-6-carboxylic acid, 10 mM in DMSO
CBNumber
CB31515852
Molecular Formula
C8H5NO3
Formula Weight
163.13
MOL File
154235-77-5.mol
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benzo[d]oxazole-6-carboxylic acid Property

Melting point:
280-290 °C (sublm)(Press: 16 Torr)
Boiling point:
350.1±15.0 °C(Predicted)
Density 
1.455±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
form 
Solid
pka
3.60±0.30(Predicted)
color 
Light brown to brown
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Safety

HS Code 
2934999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

AK Scientific
Product number
J98940
Product name
Benzo[d]oxazole-6-carboxylicacid
Packaging
1g
Price
$40
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB44071
Product name
Benzo[d]oxazole-6-carboxylic acid
Packaging
500mg
Price
$60
Updated
2021/12/16
Apolloscientific
Product number
OR110125
Product name
1,3-Benzoxazole-6-carboxylicacid
Purity
97%
Packaging
1g
Price
$106
Updated
2021/12/16
SynQuest Laboratories
Product number
4H58-1-368
Product name
1,3-Benzoxazole-6-carboxylic acid
Packaging
1g
Price
$117
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB44071
Product name
Benzo[d]oxazole-6-carboxylic acid
Packaging
2g
Price
$120
Updated
2021/12/16
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benzo[d]oxazole-6-carboxylic acid Chemical Properties,Usage,Production

Uses

6-?Benzoxazolecarboxyli?c Acid is a reactant used in the design, synthesis, structure-activity relationship, and in vivo activity of azabicyclic aryl amides as α7 nicotinic acetylcholine receptor agonists.

in vivo

Serpin B9-IN-1 (BTCA) inhibits bone metastasis (BM) in multiple tumor metastasis models. Serpin B9-IN-1 (50 mg/kg/d; ip; 14 d) effectively reduced the survival rate and metastasis proportion of metastatic cancer cells in the mouse bone metastasis model with LLC1-BM3 injected into the tail artery (CA)[1].
Serpin B9-IN-1 (300 μg/d; ip; 14 d) effectively delayed the average time to bone metastasis (BM) in the LLC1-BM3 cell group[1].

Animal Model:LLC1-BM3 Bone Metastatic Mouse Model by CA injections[1]
Dosage:50 mg/kg
Administration:ip; followed after cancer cell injection, injection daily for 14 days
Result:Reduced the survival rate and metastasis proportion of metastatic cancer cells
Animal Model:LLC1-BM3-sr-ctrl Model in Mouse[1]
Dosage:300 μg
Administration:ip; once daily for 14 days
Result:Delayed the mean time to occurrence of bone metastasis (BM), and lowered the burden of BM in LLC1-BM3-shSB9 cells group.

benzo[d]oxazole-6-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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benzo[d]oxazole-6-carboxylic acid Suppliers

China 90 India 1 United Kingdom 2 United States 14 Global 107
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154235-77-5, benzo[d]oxazole-6-carboxylic acidRelated Search:

6-Amino-2-methylbenzoxazole 6-Hydroxy-3-methyl-7-nitro-1,2-benzisoxazole (1,3-BENZOXAZOL-2-YLMETHYL)AMINE HYDROCHLORIDE 6-BROMO-5-METHYL-1,3-BENZOXAZOLE 6-AMINO-1,3-BENZOXAZOL-2(3H)-ONE 1,2-Benzisoxazol-6-ol,7-amino-3-methyl-(9CI) 3-METHYL-1,2-BENZISOXAZOLE 5-amino-7-fluorobenzo[d]oxazol-2(3H)-one 6-bromo-2-cyclopropyl-5-methylbenzo[d]oxazole 2-Chlorobenzoxazole 2-METHYL-1,3-BENZOXAZOL-5-AMINE BENZO[D]OXAZOLE-6-CARBALDEHYDE 2-Methyl-1,3-benzoxazole-6-carboxylic acid METHYL 2-(CHLOROMETHYL)-1,3-BENZOXAZOLE-6-CARBOXYLATE benzo[d]oxazole-6-carboxylic acid 2-Mercaptobenzooxazole-6-carboxylic acid methyl ester

  • benzo[d]oxazole-6-carboxylic acid
  • 1,3-Benzoxazole-6-carboxylic acid
  • 6-Benzoxazolecarboxylic acid
  • Benzoxazole-6-carboxylic Acid
  • 1,3-Benzoxazole-6-carboxylic acid 97%
  • SB9
  • Serpin B9-IN-1
  • 1,3-Benzoxazole-6-carboxylic acid, 10 mM in DMSO
  • 154235-77-5