3,4-DICHLOROPHENETHYL ALCOHOL
- Product Name
- 3,4-DICHLOROPHENETHYL ALCOHOL
- CAS No.
- 35364-79-5
- Chemical Name
- 3,4-DICHLOROPHENETHYL ALCOHOL
- Synonyms
- 3,4-Dichlorobenzyl Ethanol;3,4-Dichlorobenzeneethanol;3,4-DICHLOROPHENETHYL ALCOHOL;2-(3,4-DICHLOROPHENYL)ETHANOL;Benzeneethanol, 3,4-dichloro-;3,4-DICHLOROPHENETHYLALCOHOL 97%;2-(3,4-Dichlorophenyl)ethanol>2-(3,4-dichlorophenyl)ethan-1-ol;3,4-Dichlorophenethyl alcohol,97%;3,4-Dichlorophenethyl alcohol, 97% 5GR
- CBNumber
- CB3158566
- Molecular Formula
- C8H8Cl2O
- Formula Weight
- 191.05
- MOL File
- 35364-79-5.mol
3,4-DICHLOROPHENETHYL ALCOHOL Property
- Boiling point:
- 165 °C / 14mmHg
- Density
- 1.32
- refractive index
- 1.562-1.568
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Dichloromethane, Ethyl Acetate
- form
- Liquid
- color
- Clear colorless
- InChI
- InChI=1S/C8H8Cl2O/c9-7-2-1-6(3-4-11)5-8(7)10/h1-2,5,11H,3-4H2
- InChIKey
- GITOMJDYNUMCOV-UHFFFAOYSA-N
- SMILES
- C1(CCO)=CC=C(Cl)C(Cl)=C1
Safety
- Hazard Codes
- Xi
- Risk Statements
- 37/38-41-51-36/37/38-20/21/22
- Safety Statements
- 24/25-39-26-36/37/39
- RIDADR
- 2810
- HS Code
- 29062990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D2923
- Product name
- 2-(3,4-Dichlorophenyl)ethanol
- Purity
- >96.0%(GC)
- Packaging
- 5g
- Price
- $57
- Updated
- 2025/07/31
- Product number
- 075146
- Product name
- 2-(3,4-Dichlorophenyl)ethanol
- Purity
- 95+%
- Packaging
- 1g
- Price
- $14
- Updated
- 2021/12/16
- Product number
- BP-21062
- Product name
- 2-(3,4-dichlorophenyl)ethanol
- Purity
- 95%
- Packaging
- 1g
- Price
- $25
- Updated
- 2021/12/16
- Product number
- 075146
- Product name
- 2-(3,4-Dichlorophenyl)ethanol
- Purity
- 95+%
- Packaging
- 5g
- Price
- $35
- Updated
- 2021/12/16
- Product number
- JK175636
- Product name
- 3,4-Dichlorophenethylalcohol
- Purity
- 97%
- Packaging
- 1g
- Price
- $50
- Updated
- 2021/12/16
3,4-DICHLOROPHENETHYL ALCOHOL Chemical Properties,Usage,Production
Chemical Properties
clear colorless liquid
Uses
Intermediate in the synthesis of σ receptor ligands.
Synthesis
5807-30-7
35364-79-5
General procedure for the synthesis of 2-(3,4-dichlorophenyl)ethanol from 3,4-dichlorophenylacetic acid: 97% lithium aluminum hydride (LiAlH4, 5.54 g, 141.63 mmol) was added batchwise to an ice-bath-cooled solution of 2-(3,4-dichlorophenyl)acetic acid (19.36 g, 94.42 mmol) in tetrahydrofuran (THF, 200 mL). After the addition was completed, the reaction mixture was stirred at room temperature for 5 hours. Upon completion of the reaction, the mixture was slowly poured into ice water (150 mL) and stirring was continued for 0.5 hours. Subsequently, THF was evaporated under reduced pressure and extracted by adding dichloromethane (DCM, 200 mL). The organic layer was separated, washed with saturated saline, dried over anhydrous sodium sulfate (Na2SO4), filtered and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography (eluent: ethyl acetate/hexane=1/5, v/v) to afford the target compound 2-(3,4-dichlorophenyl)ethanol (17.14 g, 95% yield) as a colorless oil.
References
[1] Journal of Medicinal Chemistry, 2007, vol. 50, # 12, p. 2818 - 2841
[2] Journal of Medicinal Chemistry, 1990, vol. 33, # 11, p. 3100 - 3110
[3] Bioorganic and Medicinal Chemistry Letters, 2017, vol. 27, # 24, p. 5420 - 5423
[4] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 3, p. 756 - 760
[5] Journal of the American Chemical Society, 1956, vol. 78, p. 5612
3,4-DICHLOROPHENETHYL ALCOHOL Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3,4-DICHLOROPHENETHYL ALCOHOL manufacturers
- Product
- 3,4-DICHLOROPHENETHYL ALCOHOL 35364-79-5
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2019-12-24