Description References
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Butyrophenone

Description References
Product Name
Butyrophenone
CAS No.
495-40-9
Chemical Name
Butyrophenone
Synonyms
1-Phenylbutan-1-one;Butanophenone;1-PHENYL-1-BUTANONE;Propyl phenyl ketone;BUTYROPHENONE;Buterophenone;Buthrophenone;Butyrylbenzene;N-BUTYROPHENONE;N-BUTANOPHENONE
CBNumber
CB3167698
Molecular Formula
C10H12O
Formula Weight
148.2
MOL File
495-40-9.mol
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Butyrophenone Property

Melting point:
11-13 °C(lit.)
Boiling point:
228-230 °C(lit.)
Density 
1.021 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.520(lit.)
Flash point:
192 °F
storage temp. 
Store below +30°C.
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Liquid
Specific Gravity
0.988
color 
Clear colorless to yellow
Odor
at 100.00 %. camphor cherry walnut hazelnut
Odor Type
camphoreous
Water Solubility 
Insoluble in water.
BRN 
508305
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents.
LogP
2.770
CAS DataBase Reference
495-40-9(CAS DataBase Reference)
NIST Chemistry Reference
1-Butanone, 1-phenyl-(495-40-9)
EPA Substance Registry System
1-Butanone, 1-phenyl- (495-40-9)
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Safety

Hazard Codes 
Xi
Risk Statements 
41-43
Safety Statements 
26-36/37/39-24/25-23
WGK Germany 
3
TSCA 
Yes
HS Code 
29143900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H227Combustible liquid

H317May cause an allergic skin reaction

H318Causes serious eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
124338
Product name
Butyrophenone
Purity
≥99%
Packaging
25g
Price
$59
Updated
2024/03/01
Sigma-Aldrich
Product number
124338
Product name
Butyrophenone
Purity
≥99%
Packaging
100g
Price
$217
Updated
2024/03/01
TCI Chemical
Product number
B0769
Product name
Butyrophenone
Purity
>99.0%(GC)
Packaging
25mL
Price
$28
Updated
2024/03/01
TCI Chemical
Product number
B0769
Product name
Butyrophenone
Purity
>99.0%(GC)
Packaging
100mL
Price
$87
Updated
2024/03/01
Alfa Aesar
Product number
A11345
Product name
Butyrophenone, 99%
Packaging
25g
Price
$28.65
Updated
2024/03/01
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Butyrophenone Chemical Properties,Usage,Production

Description

Butyrophenone is a chemical compound with the formula C10H12O. Butyrophenone has been used to study the relationship between the electrolyte counter-ion concentration and the critical micelle concentration for several surfactants. It has been used to generate PhCO+ ions by 70 eV electron ionization. Some of its derivatives (called commonly butyrophenones) are used to treat various psychiatric disorders such as schizophrenia, as well as acting as antiemetics. They can interfere with neurotransmitter functions, usually blocking dopamine receptors, and induce behavioral, endocrine, motor-kinetic effects. Examples of butyrophenones include: Haloperidol, the most widely used classical antipsychotic drug in this class; Benperidol, the most potent commonly used antipsychotic ( 200 times more potent than chlorpromazine).

References

1. https://en.wikipedia.org/wiki/Butyrophenone
2. http://www.rightdiagnosis.com/medical/butyrophenone.htm
3. http://www.sigmaaldrich.com/catalog/product/aldrich/124338?lang=en&region=CA

Chemical Properties

colourless to yellow liquid

Uses

Butyrophenone is used as intermediates of Liquid Crystals

Uses

Intermediates of Liquid Crystals

Synthesis Reference(s)

The Journal of Organic Chemistry, 61, p. 376, 1996 DOI: 10.1021/JO951500R
Tetrahedron Letters, 30, p. 6357, 1989 DOI: 10.1016/S0040-4039(01)93893-6

Biochem/physiol Actions

Butyrophenones constitutes neuroleptic drugs and interacts with the opiate receptor by inhibiting the stereospecific binding of 3H-naloxone.

Butyrophenone Preparation Products And Raw materials

Raw materials

Preparation Products

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Butyrophenone Suppliers

Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Fax
+86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2210
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94838
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18501085097
Fax
010-89508210
Email
sales3.gd@hwrkchemical.com
Country
China
ProdList
7583
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9551
Advantage
66
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9816
Advantage
59
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View Lastest Price from Butyrophenone manufacturers

Hebei Guanlang Biotechnology Co., Ltd.
Product
Butyrophenone 495-40-9
Price
US $10.00/KG
Min. Order
1KG
Purity
99.5%
Supply Ability
100
Release date
2020-11-19
Zhuozhou Wenxi import and Export Co., Ltd
Product
Butyrophenone, Phenyl n-propyl ketone 495-40-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
Butyrophenone 495-40-9
Price
US $1.80-3.60/KG
Min. Order
1KG
Purity
98%
Supply Ability
88kg
Release date
2019-07-30

495-40-9, ButyrophenoneRelated Search:


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