JC-1
- Product Name
- JC-1
- CAS No.
- 47729-63-5
- Chemical Name
- JC-1
- Synonyms
- CBIC2;D 383;NK 1420;CBIC2(3);JC-1 IODIDE;D 383 (DYE);6' - tetrachloro - 1;3' - tetraethylbenzimidazolylcarbocyanine iodide;1,1',3,3'-TETRAETHYL-5,5',6,6'-TETRACHLOROIMIDACARBOCYANINE IODIDE;BIS(5,6-DICHLORO-1,3-DIETHYL-2-BENZIMIDAZOLE)TRIMETHINECYANINE IODIDE
- CBNumber
- CB3168099
- Molecular Formula
- C25H27Cl4IN4
- Formula Weight
- 652.22
- MOL File
- 47729-63-5.mol
JC-1 Property
- storage temp.
- -20C
- form
- solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 420200
- Product name
- JC-1 - CAS 47729-63-5 - Calbiochem
- Packaging
- 5mg
- Price
- $476
- Updated
- 2024/03/01
- Product number
- 452847
- Product name
- JC-1 iodide
- Packaging
- 1mg
- Price
- $425
- Updated
- 2021/12/16
- Product number
- 1809AH
- Product name
- 5,6-Dichloro-2-(1-(3-(5,6-dichloro-1,3-diethyl-2-benzimidazolylidene)propenyl))-1,3-diethylbenzimidazoliumiodide
- Packaging
- 10mg
- Price
- $178
- Updated
- 2021/12/16
- Product number
- BISN0055
- Product name
- JC-1
- Purity
- 99%
- Packaging
- 5mg
- Price
- $254
- Updated
- 2021/12/16
JC-1 Chemical Properties,Usage,Production
Uses
JC-1 is commonly used to determine mitochondrial membrane potential. It is a cationic carbocyanine dye that is membrane permeable and is often used for flow cytometry and fluorescent microscopy. This dye changes color as the membrane potential increases. At higher potentials, JC-1 forms aggregates, which changes the fluorescence emission color from green to red. Dyes and metabolites.
Definition
ChEBI: 1,1',3,3'-tetraethyl-5,5',6,6'-tetrachloroimidacarbocyanine iodide is a cyanine dye and an organic iodide salt. It has a role as a fluorochrome. It contains a 1,1',3,3'-tetraethyl-5,5',6,6'-tetrachloroimidacarbocyanine.
General Description
A cationic, fluorescent, carbocyanine dye that can be used as a ratiometric indicator of mitochondrial potential ΔΨm in cells, tissues, and isolated mitochondria. It labels mitochondria with high membrane potential orange and mitochondria with low membrane potential green. Mitochondrial depolarization is indicated by a decrease in the red/green fluorescence intensity ratio. Ideal for detection of collapse of ΔΨm induced by uncouplers of mitochondrial respiration. The potential-sensitive color shift is due to concentration-dependent formation of red fluorescent J-aggregates. JC-1 has also been used in a functional assay of multidrug-resistance cells and in apoptosis-related mitochondrial modifications.
Biochem/physiol Actions
Product does not compete with ATP.
storage
-20°C
JC-1 Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from JC-1 manufacturers
- Product
- JC-1 47729-63-5
- Price
- US $0.00/mg
- Min. Order
- 25mg
- Purity
- >99.00%
- Supply Ability
- 25mg
- Release date
- 2024-03-29