ChemicalBook > CAS DataBase List > 17ALPHA-HYDROXYPREGNENOLONE

17ALPHA-HYDROXYPREGNENOLONE

Product Name
17ALPHA-HYDROXYPREGNENOLONE
CAS No.
387-79-1
Chemical Name
17ALPHA-HYDROXYPREGNENOLONE
Synonyms
NSC 63853;17-OH PREG;17alpha-Hydroxy;17-OH Pregnenolone;Dronedarone HCl-d6;Hydroxypregnenolone;17a-Hydroxypregnolone;17A-HYDROXYPREGENOLONE;17-HYDROXYPREGNENOLONE;17α-Hydroxypregnenolone
CBNumber
CB3175435
Molecular Formula
C21H32O3
Formula Weight
332.48
MOL File
387-79-1.mol
More
Less

17ALPHA-HYDROXYPREGNENOLONE Property

Melting point:
273℃
Flash point:
9℃
storage temp. 
-20°C
solubility 
Chloroform (Slightly), DMSO (Slightly, Heated, Sonicated)
form 
Solid
Boiling point:
478.4±45.0 °C(Predicted)
Density 
1.15±0.1 g/cm3(Predicted)
pka
13.02±0.70(Predicted)
color 
White to Off-White
CAS DataBase Reference
387-79-1(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
F,T
Risk Statements 
11-23/24/25-39/23/24/25
Safety Statements 
7-16-36/37-45
RIDADR 
UN1230 - class 3 - PG 2 - Methanol
WGK Germany 
3
RTECS 
TU5548000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H370Causes damage to organs

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P311Call a POISON CENTER or doctor/physician.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H5002
Product name
17α-Hydroxypregnenolone
Packaging
5g
Price
$562
Updated
2024/03/01
Sigma-Aldrich
Product number
H-105
Product name
17α-Hydroxypregnenolone solution
Purity
100?μg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
Packaging
1mL
Price
$128
Updated
2024/03/01
Sigma-Aldrich
Product number
S518034
Product name
3BETA,17ALPHA-DIHYDROXYPREGN-5-EN-20-ONE
Purity
AldrichCPR
Packaging
250MG
Price
$28.6
Updated
2022/05/15
Sigma-Aldrich
Product number
R199400
Product name
3-BETA,17-ALPHA-DIHYDROXYPREGN-5-EN-20-ONE
Purity
AldrichCPR
Packaging
1MG
Price
$28.6
Updated
2022/05/15
Cayman Chemical
Product number
29181
Product name
17α-hydroxy Pregnenolone
Packaging
100mg
Price
$44
Updated
2024/03/01
More
Less

17ALPHA-HYDROXYPREGNENOLONE Chemical Properties,Usage,Production

Description

17α-hydroxy Pregnenolone is a metabolite of pregnenolone and a precursor in the biosynthesis of dehydroepiandrosterone (DHEA; ). It is formed from pregnenolone by cytochrome P450 (CYP) isoform CYP17A1 hydroxylase activity and then converted to dehydroepiandrosterone by CYP17A1-mediated 17,20-lyase activity. Plasma levels of 17α-hydroxy pregnenolone are elevated in patients with type II 3β-hydroxysteroid dehydrogenase deficiency, a form of congenital adrenal hyperplasia.

Uses

17α-hydroxypregnenolone has been used as a substrate for the enzyme 3β‐hydroxysteroid dehydrogenase (3β‐HSD) expressed in COS1 cells.

General Description

17α-hydroxypregnenolone is a derived from pregnenolone.

Biochem/physiol Actions

17α-hydroxypregnenolone acts as a precursor for cortisol and sex steroids.

17ALPHA-HYDROXYPREGNENOLONE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

17ALPHA-HYDROXYPREGNENOLONE Suppliers

China 52 Europe 2 Germany 3 India 1 Poland 1 Switzerland 1 United Kingdom 7 United States 24 Global 91
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40240
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Fax
0086-21-51320502
Email
tauto@tautobiotech.com
Country
China
ProdList
3989
Advantage
66
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17994
Advantage
56
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
15878
Advantage
55
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Alta Scientific Co., Ltd.
Tel
022-6537-8550 15522853686
Fax
022-2532-9655
Email
sales@altasci.com.cn
Country
China
ProdList
4515
Advantage
55
Aikon International Limited
Tel
025-58859352 18068836627
Fax
02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
15085
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6870
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 13028896684
Email
sales@rrkchem.com
Country
China
ProdList
55896
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11289
Advantage
58
ShangHai Anpel Co, Ltd.
Tel
18501792038; 18501792038
Email
shanpel@anpel.com.cn
Country
China
ProdList
9614
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
025-85560043 13675144456
Fax
025-85563444
Email
sean.lv@synzest.com
Country
China
ProdList
11442
Advantage
58
Qingdao Tenglong microwave technology co., LTD.
Tel
0532-83818797 18561885118
Email
market@tlwb.com.cn
Country
China
ProdList
3946
Advantage
58
Manhag Testing Technology Co., Ltd
Tel
020-020-3846236 17688849268
Email
2443244976@qq.com
Country
China
ProdList
7775
Advantage
58
TCI (Shanghai) Chemical Trading Co., Ltd.
Tel
021-61109150
Fax
021-61105897
Email
sales@tcisct.com
Country
China
ProdList
31163
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
29778
Advantage
58
Yancheng Tongming Biotechnology Co., Ltd.
Tel
15195160625
Email
2863565288@qq.com
Country
China
ProdList
5194
Advantage
58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd
Tel
17691182729 18161915376
Email
1046@dideu.com
Country
China
ProdList
10010
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24023
Advantage
58
LGC Science (Shanghai) Ltd.
Tel
17717235263
Email
cindy.yang@lgcgroup.com
Country
China
ProdList
11572
Advantage
58
Shanghai Yiyan Biotechnology Co. , Ltd.
Tel
021-69985186 13611928337
Email
3427709316@qq.com
Country
China
ProdList
7984
Advantage
58
Shanghai isotope chemical co.,ltd
Tel
021-021-51600108 13062666369
Email
sales@chinaisotope.com
Country
China
ProdList
4272
Advantage
58
Shanghai Saikerui Biotechnology Co. , Ltd.
Tel
021-58000709 15900491054
Email
info@scrbio.com
Country
China
ProdList
9260
Advantage
58
Nantong QuanYi Biotechnology Co., Ltd
Tel
0513-66337626 18051384581
Email
sales@chemhifuture.com
Country
China
ProdList
4031
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
8740
Advantage
58
Shanghai Beiwanta Biotechnology Co., Ltd.
Tel
021-67187366 19901745723
Email
info@bwtlab.com
Country
China
ProdList
9247
Advantage
58
Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd
Tel
18162595016
Email
3287908757@qq.com
Country
China
ProdList
9887
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
025-85560043 15850508050
Fax
025-85563444
Email
cindy.huang@synzest.com
Country
China
ProdList
12007
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
17301488900
Fax
025-85560043
Email
judy.xia@synzest.com
Country
China
ProdList
12584
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
025-85560043 15850508050
Fax
025-85563444
Email
rose.shi@synzest.com
Country
China
ProdList
6210
Advantage
58
Shanghai Aladdin Biochemical Technology Co.,Ltd.
Tel
+86-18521732826
Email
market@aladdin-e.com
Country
China
ProdList
48467
Advantage
58
ZhengZhou Edward Biology Co.,Ltd
Tel
13298105281 13298105281
Email
1522334715@qq.com
Country
China
ProdList
7496
Advantage
58
RD International Technology Co., Limited
Tel
18024082417
Email
market@ubiochem.com
Country
China
ProdList
9180
Advantage
58
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6846
Advantage
58
Shanghai Shifeng Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
2279790755@qq.com
Country
CHINA
ProdList
5572
Advantage
58
Shanghai Yuduo Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
3128828699@qq.com
Country
CHINA
ProdList
6509
Advantage
58
Shanghai Yubai Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
rongbai_sh021@163.com
Country
CHINA
ProdList
6723
Advantage
58
Shanghai yiji industries Co., Ltd.
Tel
--
Fax
--
Email
yiji01@foxmail.com
Country
China
ProdList
6294
Advantage
50
Beijing Hengye Zhongyuan Chemical Co., Ltd
Tel
--
Fax
--
Email
13552281129@163.com
Country
China
ProdList
6168
Advantage
64

387-79-1, 17ALPHA-HYDROXYPREGNENOLONERelated Search:

21-hydroxypregnenolone 3-acetate 17ALPHA-HYDROXYPREGNENOLONE-3,17-DIACETATE,17-HYDROXYPREGNENOLONE DIACETATE,17A-HYDROXYPREGNENOLONE-3,17-DIACETATE,17ALPHA-HYDROXYPREGNENOLONE-3,17-DIACETATE Pregnenolone 16BETA-METHYL-17ALPHA-HYDROXYPREGNENOLONE,16BETA-METHYL-17ALPHA-HYDROXYPREGNENOLONE 17ALPHA-HYDROXYPREGNENOLONE 17-ACETATE,17ALPHA-HYDROXYPREGNENOLONE 17-ACETATE,17A-HYDROXYPREGNENOLONE-17-ACETATE 17-HYDROXYPREGNENOLONE 3-ACETATE,17ALPHA-HYDROXYPREGNENOLONE 3-ACETATE,17A-hydroxypregnenolone 3-acetate,17ALPHA-HYDROXYPREGNENOLONE 3-ACETATE 20-BETA-HYDROXYPREGNENOLONE 6-methyl-17alpha-hydroxypregnenolone diacetate,6-methyl-17alpha-hydroxypregnenolone diacetate 16-METHYLENE-17ALPHA-HYDROXYPREGNENOLONE 3-ACETATE 16-ALPHA-HYDROXYPREGNENOLONE,16-ALPHA-HYDROXYPREGNENOLONE-3-SULFATE,16A-hydroxypregnenolone 11-BETA-HYDROXYPREGNENOLONE 21-HYDROXYPREGNENOLONE 3,21-DIACETATE 17ALPHA-HYDROXYPREGNENOLONE-21,21,21-D3 21-HYDROXYPREGNENOLONE HYDROXYPREGNENOLONE, 17a-(RG) 17-HYDROXYPREGNENOLONE-7-CM:BSA 17-HYDROXYPREGNENOLONE CARBOXYMETHYLOXIME,17-HYDROXYPREGNENOLONE CARBOXYMETHYLOXIME:BSA 21-HYDROXYPREGNENOLONE 21-SODIUM SULPHATE

  • 17alpha-Hydroxy
  • (3b)-3,17-dihydroxy-Pregn-5-en-20-one
  • 17a-Hydroxypregnolone
  • 17ALPHA-LPHA-HYDROXYPREGNENOLONE
  • 5-Pregnen-3b,17-dihydroxy-3-one
  • 3β,17α-Dihydroxy-5-pregnen-20-one, 5-Pregnene-3β,17α-diol-20-one
  • 17-OH PREG
  • 17-OH Pregnenolone
  • 3β,17-Dihydroxypregn-5-en-20-one
  • 3β,17α-Dihydroxypregn-5-en-20-one
  • 3-beta,17-dihydroxypregn-5-en-20-one
  • 3-beta,17-alpha-dihydroxypregn-5-en-20-one
  • Hydroxypregnenolone
  • 17ALPHA-LPHA-HYDROXYPREGNENOLONE 3H ASSAY ASSAY CHARACTERISTICS
  • 17ALPHA-LPHA-HYDROXYPREGNENOLONE (1,2-3 H)
  • 17ALPHA-LPHA-HYDROXYPREGNENOLONE 3H RIA KIT ASSAY CHARACTERISTICS
  • 17ALPHA-LPHA-HYDROXYPREGNENOLONE CRYSTALLINE
  • Pregn-5-en-20-one, 3,17-dihydroxy-, (3β)-
  • 17α-Hydroxypregnenolone,3β,17α-Dihydroxy-5-pregnen-20-one, 5-Pregnene-3β,17α-diol-20-one
  • NSC 63853
  • 3β,17α-Dihydroxy-5-pregnen-20-one
  • 5-Pregnene-3β,17α-diol-20-one
  • 17α-Hydroxypregnenolone solution
  • 17α-hydroxypregnenolone solution,100ppm
  • 3B 17A-DIHYDROXYPREGN-5-EN-20-ONE
  • 3BETA,17ALPHA-DIHYDROXY-DELTA5-PREGNEN-20-ONE
  • 3BETA,17ALPHA-DIHYDROXY-5-PREGNEN-20-ONE
  • 3-BETA,17-DIHYDROXY-5-PREGNEN-3-ONE
  • 5-PREGNENE-3BETA,17ALPHA-DIOL-20-ONE
  • 5-PREGNEN-3-BETA, 17-DIOL-20-ONE
  • 5-PREGNEN-3BETA-17A-DIOL-20-ONE
  • 5-PREGNEN-3BETA,17ALPHA-DIOL-20-ONE
  • 17-dihydroxy-(3-beta)-pregn-5-en-20-on
  • 3-beta,17-dihydroxy-pregn-5-en-20-on
  • HYDROXYPREGNENOLONE, 17A-
  • 17A-HYDROXYPREGENOLONE
  • 17A-HYDROXY PREGNENOLONE
  • 17ALPHA-HYDROXYPREGNENOLONE
  • 17-HYDROXYPREGNENOLONE
  • 17alpha-Hydroxypregnenolone-20,21-13C2,16,16-d2
  • 17α-Hydroxypregnenolone
  • 3b,17-Dihydroxy-5-pregnen-20-one
  • 17α-Hydroxypregnenolone (Solution)
  • "17A-HYDROXY PREGNENOLONE 13C2,D2"
  • Inhibitor,17a Hydroxypregnenolone,Endogenous Metabolite,17aHydroxypregnenolone,inhibit,17a-Hydroxypregnenolone
  • Dronedarone HCl-d6
  • 5-PREGNEN-3β, 17-DIOL-20-ONE
  • 387-79-1
  • Steroids