1-NITROHEXANE Property

Melting point:

23.5°C (estimate)

Boiling point:

91-92 °C/24 mmHg (lit.)

Density 

0.94 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.423(lit.)

Flash point:

72 °C

storage temp. 

-20°C Freezer

solubility 

Dichloromethane, Chloroform, Ethyl Acetate, Methanol

form 

Clear Colourless Liquid

pka

8.65±0.29(Predicted)

BRN 

1749466

Stability:

Stable. Incompatible with strong bases, strong oxidizing agents.

EPA Substance Registry System

1-Nitrohexane (646-14-0)

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

RIDADR 

2810

WGK Germany 

3

F 

8

HazardClass 

6.1(b)

PackingGroup 

III

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

1-NITROHEXANE Chemical Properties,Usage,Production

Chemical Properties

Colourless Liquid

Uses

1-Nitrohexane is used in method for preparing amine by reducing nitro compound with pinacolborane under catalysis of cyclic (alkyl) (amino) carbene chromium complex.

Definition

ChEBI: 1-nitrohexane is a primary nitroalkane that is hexane substituted by a nitro group at position 1. It has a role as a human urinary metabolite. It derives from a hydride of a hexane.

Synthesis Reference(s)

The Journal of Organic Chemistry, 44, p. 659, 1979 DOI: 10.1021/jo01318a050
Synthesis, p. 835, 1978 DOI: 10.1055/s-1978-24907

General Description

Clear colorless liquid. Insoluble in water.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Nitroalkanes, such as 1-NITROHEXANE, range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction that culminates in a detonation. Nitroalkanes are milder oxidizing agents, but still react violently with reducing agents at higher temperature and pressures. Nitroalkanes react with inorganic bases to form explosive salts. The presence of metal oxides increases the thermal sensitivity of nitroalkanes. Nitroalkanes with more than one nitro group are generally explosive. Nitroalkanes are insoluble in water. Flammable/combustible material. May be ignited by heat, sparks or flames.

Fire Hazard

Flash point data for 1-NITROHEXANE are not available. 1-NITROHEXANE is combustible.