PROPARACAINE
- Product Name
- PROPARACAINE
- CAS No.
- 298-50-0
- Chemical Name
- PROPARACAINE
- Synonyms
- promecaine;PROPARACAINE;propantheline;Propanthelinium;PROPARACAINE USP/EP/BP;Proparacaine Propantheline;Diisopropylmethyl[2-(9H-xanthene-9-ylcarbonyloxy)ethyl]aminium;diisopropyl-methyl-[2-(9H-xanthene-9-carbonyloxy)ethyl]ammonium;[2-[(9H-Xanthen-9-ylcarbonyl)oxy]ethyl]diisopropylmethylaminium;methyl-di(propan-2-yl)-[2-(9H-xanthene-9-carbonyloxy)ethyl]azanium
- CBNumber
- CB3181470
- Molecular Formula
- C16H26N2O3
- Formula Weight
- 294.39
- MOL File
- 298-50-0.mol
PROPARACAINE Property
- pka
- pKa 3.22(H2O) (Uncertain)
Safety
- Hazardous Substances Data
- 298-50-0(Hazardous Substances Data)
N-Bromosuccinimide Price
- Product number
- API0006939
- Product name
- PROPANTHELINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $505.47
- Updated
- 2021/12/16
PROPARACAINE Chemical Properties,Usage,Production
Uses
Anticholinergic.
Uses
Propantheline is used for treating stomach ulcers.
Definition
ChEBI: Propantheline is a member of xanthenes.
brand name
Pro-Banthine (Searle).
Pharmacology
The pharmacological action of propantheline is qualitatively similar to atropine. It has a weaker effect on the CNS than atropine. Unlike atropine, it exhibits greater ganglioblocking action than antimuscarinic action. Moreover, upon overdose it causes neuromuscular curare-like blockage.
Synthesis
Propanetheline, N-methyl-N-(1-methylethyl)-N-[2-[(9H-xanthen-9- ylcarbonyl) oxy]ethyl]-2-propanaminium bromide (14.1.11), is synthesized by reacting xanthen-9-carboxylic acid chloride with 2-di-iso-propylaminoethanol, giving the ester (14.1.10), which upon reaction with methylbromide turns into the quaternary salt, propantheline (14.1.11) [12,13].
Veterinary Drugs and Treatments
Proparacaine is a rapid acting topical anesthetic useful for a variety of ophthalmic procedures including tonometry (intraocular pressure measurement), relief of corneal pain to facilitate examination, biopsy/sample collection, and to distinguish between corneal and uveal pain. Proparacaine primarily anesthetizes the cornea; with limited penetration into conjunctiva. Anesthesia is of short duration (5 – 10 minutes).
PROPARACAINE Preparation Products And Raw materials
Raw materials
Preparation Products
PROPARACAINE Suppliers
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View Lastest Price from PROPARACAINE manufacturers
- Product
- Propantheline 298-50-0
- Price
- US $50.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 20 tons
- Release date
- 2023-09-05
- Product
- Proparacaine 298-50-0
- Price
- US $30.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2023-09-27
- Product
- Propantheline 298-50-0
- Price
- US $10.00/Kg/Bag
- Min. Order
- 1Kg/Bag
- Purity
- 99%
- Supply Ability
- 20 Tons
- Release date
- 2021-11-03