N-Methylolacrylamide

Product Name: N-Methylolacrylamide
CAS No.: 924-42-5
Chemical Name: N-Methylolacrylamide
Synonyms: N-(HYDROXYMETHYL)ACRYLAMIDE;METHYLOLACRYLAMIDE;N-MAN;N-MAN PC;HINT;NM-AMD;PRKCNH1;uraminet80;Rocagil BT;NCI-C60333
CBNumber: CB3182194
Molecular Formula: C4H7NO2
Formula Weight: 101.1
MOL File: 924-42-5.mol

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N-Methylolacrylamide Property

Melting point:: 74-75°C
Boiling point:: 277°C(lit.)
Density: 1.082 g/mL at 20 °C
vapor pressure: 31 hPa (25 °C)
refractive index: n20/D 1.413
Flash point:: 100°C
storage temp.: Store at <= 20°C.
solubility: Chloroform (Slightly), Methanol (Slightly)
pka: 13.25±0.10(Predicted)
form: Solid
Specific Gravity: 1.074
color: White to Off-White
PH: 6.0-7.0 (H2O, 20°C)
Water Solubility: <0.1 g/100 mL at 20.5 ºC
BRN: 506646
Stability:: Light Sensitive, Moisture Sensitive
InChI: 1S/C4H7NO2/c1-2-4(7)5-3-6/h2,6H,1,3H2,(H,5,7)
InChIKey: CNCOEDDPFOAUMB-UHFFFAOYSA-N
SMILES: OCNC(=O)C=C
LogP: -1.81 at 20℃ and pH7
CAS DataBase Reference: 924-42-5(CAS DataBase Reference)
NIST Chemistry Reference: 2-Propenamide, n-(hydroxymethyl)-(924-42-5)
IARC: 3 (Vol. 60) 1994
EPA Substance Registry System: N-Methylolacrylamide (924-42-5)

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Safety

Hazard Codes: Xn,T
Risk Statements: 22-36/37/38-62-48/20/21/22-43-46-45
Safety Statements: 26-45-36/37-53
RIDADR: 2810
WGK Germany: 3
RTECS: AS3600000
TSCA: TSCA listed
HazardClass: 4.1
PackingGroup: III
HS Code: 29241990
Storage Class: 6.1D - Non-combustible acute toxic Cat.3
toxic hazardous materials or hazardous materials causing chronic effects
Hazard Classifications: Acute Tox. 3 Oral
Carc. 1B
Muta. 1B
Repr. 2
Skin Sens. 1
STOT RE 1
STOT RE 2 Oral
Hazardous Substances Data: 924-42-5(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H317May cause an allergic skin reaction

H340May cause genetic defects

H350May cause cancer

H361Suspected of damaging fertility or the unborn child

H372Causes damage to organs through prolonged or repeated exposure

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.20675
Product name: N-(Hydroxymethyl)acrylamide
Purity: (48% aqueous solution) (stabilised with hydroquinone monomethyl ether) for synthesis
Packaging: 100mL
Price: $41.4
Updated: 2025/07/31

Sigma-Aldrich

Product number: 245801
Product name: N-(Hydroxymethyl)acrylamide solution
Purity: 48 wt. % in H2O
Packaging: 100g
Price: $92.1
Updated: 2025/07/31

Sigma-Aldrich

Product number: 245801
Product name: N-(Hydroxymethyl)acrylamide solution
Purity: 48 wt. % in H2O
Packaging: 1kg
Price: $161
Updated: 2025/07/31

Sigma-Aldrich

Product number: 8.20675
Product name: N-(Hydroxymethyl)acrylamide
Purity: (48% aqueous solution) (stabilised with hydroquinone monomethyl ether) for synthesis
Packaging: 1L
Price: $69.2
Updated: 2024/03/01

TCI Chemical

Product number: M0574
Product name: N-(Hydroxymethyl)acrylamide
Purity: >98.0%(T)
Packaging: 25g
Price: $27
Updated: 2025/07/31

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N-Methylolacrylamide Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

N-(Hydroxymethyl)acrylamide can be used as:

A monomer in the development of polymer gel dosimeters specifically designed for radiation therapy applications. The incorporation of NHMA enhances the sensitivity of the dosimeter to radiation doses.
A monomer in the development of thermo-responsive polymeric gates, which exhibits thermo-responsive behavior. The incorporation of NHMA enhances the overall properties of the polymer, allowing for better control over the release mechanisms in response to temperature changes.
A key monomer in the synthesis of double-hydrophilic and amphiphilic block glycopolymers, contributing to their self-assembly properties, biocompatibility, and functionalization potential. These characteristics make NHMA-based glycopolymers valuable for various biomedical applications, including drug delivery systems, biosensors, and tissue engineering.

Definition

ChEBI: N-Methylolacrylamide is a secondary carboxamide.

General Description

A colorless or yellow aqueous solution.

Air & Water Reactions

Soluble in water.

Reactivity Profile

N-Methylolacrylamide may be sensitive to prolonged exposure to light. Polymerization and generation of heat and flames may occur on exposure to to heat or contaminants. Incompatible with strong oxidizers.

Fire Hazard

Literature sources indicate that N-Methylolacrylamide is nonflammable.

Synthesis

(1), the acrylamide is added to the reaction kettle containing solvent acetone, the polymerization blocking agent is added, and the temperature is raised to 42??45??;

(2), adding catalyst sodium methanol, adjusting the pH value in the reaction solution to 8.88;

(3), adding formaldehyde, adjusting the pH of the reaction solution to 8.5, and reacting at constant temperature for 1 hour;

(4), add phthalic acid, adjust its reaction solution pH to 7.2;

(5), cooling, crystallization, filtration to get the finished product N-hydroxymethacrylamide.

N-Methylolacrylamide Preparation Products And Raw materials

Raw materials

Acrylamide Formaldehyde Acrylonitrile

Preparation Products

Adhesive for nonwoven fabric Binder for coating printing

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N-Methylolacrylamide Suppliers

Americas 1 Australia 1 Brazil 1 China 383 Europe 2 France 1 Germany 6 India 5 Indonesia 1 Japan 4 Switzerland 2 The Netherlands 2 United Kingdom 3 United States 27 USA 1 Global 440

-Lianyungang Hengshun Chemical Co., Ltd.

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3B Pharmachem (Wuhan) International Co.,Ltd.

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View Lastest Price from N-Methylolacrylamide manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: N-Methylolacrylamide 924-42-5
Price: US $2.00-6.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-07-29

Shaanxi Dideu New Materials Co. Ltd

Product: N-Methylolacrylamide 924-42-5
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-04-29

Hebei Chuanghai Biotechnology Co., Ltd

Product: N-Methylolacrylamide 924-42-5
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 5tons
Release date: 2024-12-06

924-42-5, N-Methylolacrylamide Related Search:

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PRKCNH1

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924-42-5

942-42-5

C4H7O2N

CH2CHCONHCH2OH

H2CCCH3CONHOH

AMINE

fine chemicals

Acrylamide and Methacrylamide

Acrylic Monomers

Monomers

924-42-5