N-NITROSOMORPHOLINE

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N-NITROSOMORPHOLINE

Product Name: N-NITROSOMORPHOLINE
CAS No.: 59-89-2
Chemical Name: N-NITROSOMORPHOLINE
Synonyms: NMOR;NSC 139;nci-c02164;M2-Impurity D;N-Nitrosomorfolin;NITROSOMORPHOLINE;N-Nitrosomorpholin;4-Nitrosomorpholine;4-nitroso-morpholin;n-nitroso-morpholin
CBNumber: CB3185221
Molecular Formula: C4H8N2O2
Formula Weight: 116.12
MOL File: 59-89-2.mol

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N-NITROSOMORPHOLINE Property

Melting point:: 29°C
Boiling point:: 225℃
Density: 1.2829 (rough estimate)
refractive index: 1.4880 (estimate)
Flash point:: 29 °C
storage temp.: 2-8°C
Water Solubility: Completely soluble in water
solubility: DMSO : 100 mg/mL (861.18 mM)
form: <29°C Solid,>29°C Liquid
pka: -5.72±0.20(Predicted)
color: White or Colorless to Yellow
Merck: 14,6640
Stability:: Stable, but light-sensitive. Combustible. Incompatible with strong oxidizing agents. Refrigerate, store in the dark.
IARC: 2B (Vol. 17, Sup 7) 1987
EPA Substance Registry System: N-Nitrosomorpholine (59-89-2)

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Safety

Hazard Codes: Xn,T,F
Risk Statements: 22-40-39/23/24/25-23/24/25-11
Safety Statements: 36/37-45-16-7
RIDADR: UN 2810 6.1/PG 3
WGK Germany: 3
RTECS: QE7525000
HS Code: 2934.99.9001
HazardClass: 6.1(b)
PackingGroup: III
Hazardous Substances Data: 59-89-2(Hazardous Substances Data)
Toxicity: LD50 orally in rats: 282 mg/kg (Druckrey)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: N7382
Product name: Nitrosomorpholine
Packaging: 1ml
Price: $158
Updated: 2024/03/01

Sigma-Aldrich

Product number: N7382
Product name: Nitrosomorpholine
Packaging: 5ml
Price: $322.2
Updated: 2024/03/01

TCI Chemical

Product number: N0466
Product name: N-Nitrosomorpholine
Purity: >99.0%(GC)
Packaging: 5g
Price: $253
Updated: 2024/03/01

TCI Chemical

Product number: N0466
Product name: N-Nitrosomorpholine
Purity: >99.0%(GC)
Packaging: 25g
Price: $748
Updated: 2024/03/01

Sigma-Aldrich

Product number: Y0000822
Product name: Molsidomine impurity B
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: y0000822
Price: $150
Updated: 2024/03/01

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N-NITROSOMORPHOLINE Chemical Properties,Usage,Production

Chemical Properties

yellow crystals or gold liquid

Uses

Solvent for polyacrylonitrile; present during rubber manufacturing

Uses

N-Nitrosomorpholine, a frequently used genotoxic model carcinogen. Toxicogenomic analysis of N-Nitrosomorpholine induced changes in rat liver.

Definition

ChEBI: A nitrosamine that is morpholine in which the hydrogen attached to the nitrogen is replaced by a nitroso group. A carcinogen and mutagen, it is found in snuff tobacco.

Synthesis Reference(s)

Synthetic Communications, 22, p. 2607, 1992 DOI: 10.1080/00397919208021659

General Description

Yellow crystals. Golden liquid with many crystals at 68°F.

Air & Water Reactions

Water soluble.

Reactivity Profile

N-NITROSOMORPHOLINE is incompatible with strong oxidizing agents .

Health Hazard

ACUTE/CHRONIC HAZARDS: When heated to decomposition N-NITROSOMORPHOLINE emits toxic fumes of nitrogen oxides.

Fire Hazard

Flash point data for N-NITROSOMORPHOLINE are not available; however, N-NITROSOMORPHOLINE is probably combustible.

Biochem/physiol Actions

Tumor initiator in rodent liver, trachea, nasal cavity, esophagus, kidney, lung, and thyroid.

Safety Profile

Confirmed carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. Moderately toxic by inhalation. Human mutation data reported. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx. See also N-NITROSO COMPOUNDS.

Carcinogenicity

N-Nitrosomorpholine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

N-NITROSOMORPHOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from N-NITROSOMORPHOLINE manufacturers

ShenZhen H&D Pharmaceutical Technology Co., LTD

Product: N-nitrosomorpholine 59-89-2
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 0.98
Supply Ability: 10g
Release date: 2024-04-26

59-89-2, N-NITROSOMORPHOLINERelated Search:

4-Acryloylmorpholine N-Nitrosodibutylamine N-NITROSOMORPHOLINE N-NITROSOMORPHOLINE-D8 N-nitroso-2-hydroxymorpholine Morpholine, 4-nitro- (6CI, 7CI, 8CI, 9CI) CIS-N-NITROSO-2,6-DIMETHYLMORPHOLINE 4-NITROSO-MORPHOLIN-3-OL N-nitroso-2-methoxy-2,6-dimethylmorpholine 2,6-DIMETHYL-N-NITROSOMORPHOLINE,2,6-Dimethyl-4-nitrosomorpholine 5-pentyl-N-nitrosomorpholine N-NITROSOMORPHOLINE SOLUTION 100UG/ML IN METHANOL 5X1ML MOLSIDOMINE IMP. B (PHARMEUROPA): 4-NITROSOMORPHOLINE N-NITROSOMORPHOLINE SOLUTION 100UG/ML IN METHANOL 5ML 2-HYDROXY-N-NITROSOMORPHOLINE 3,5-Dimethyl-4-nitrosomorpholine N-NITROSOMORPHOLINE SOLUTION 100UG/ML IN METHANOL 1ML 4-NITROSO-MORPHOLINE-3-CARBOXYLIC ACID

4-nitroso-morpholin

4-Nitrosomorpholine

Morpholine, N-nitroso-

Morpholine,4-nitroso-

N-Nitrosomorpholine 100mg [59-89-2]

NSC 139

nci-c02164

nitrosomorpholineisopac

NMOR

N-Nitrosomorfolin

N-Nitrosomorpholin

n-nitroso-morpholin

NITROSOMORPHOLINE

N-NITROSOMORPHOLINE

N-NITROSOMORPHOLINE, 1X1ML, MEOH, 5000UG /ML

n-nitrosomorpholine solution

N-Nitrosomorpholine @5.0 mg/mL in MeOH

Molsidomine impurity B CRS

N-Nitrosomorpholine@100 μg/mL in Dichloromethane

N-Nitrosomorpholine&gt

N-NitrosomorpholineSolution,5,000mg/L,1ml

N-Nitrosomorpholine,inhibit,N Nitrosomorpholine,Inhibitor,NNitrosomorpholine

4-Nitrosomorpholine 0.1 mg/ml in Methanol

4-Nitrosomorpholine 1.0 mg/ml in Methanol

N-nitroso-morpholine, NMOR3,7

N-Nitrosomorpholine 10.0 μg/ml Methanol

M2-Impurity D

59-89-2

Mutagenesis Research Chemicals

Nitric Oxide Reagents

Nitrosamine

pharmacetical

Alpha Sort

NA - NI

N-OAlphabetic

Volatiles/ Semivolatiles