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LINOLEOYLETHANOLAMIDE

Product Name
LINOLEOYLETHANOLAMIDE
CAS No.
68171-52-8
Chemical Name
LINOLEOYLETHANOLAMIDE
Synonyms
LEA;ODNHETOH;Einecs 269-029-6;LINOLEYLETHANOLAMIDE;Anandamide (18:2,n6);Linoleic ethanolamine;LINOLEOYLETHANOLAMIDE;Linoleic ethanolamide;Linoleoyl monoethanolamide;N-lineleoyl Ethanolamide (LEA)
CBNumber
CB3185498
Molecular Formula
C20H37NO2
Formula Weight
323.51
MOL File
68171-52-8.mol
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LINOLEOYLETHANOLAMIDE Property

Melting point:
38-40 °C
Boiling point:
499.1±38.0 °C(Predicted)
Density 
0.926±0.06 g/cm3(Predicted)
Flash point:
14 °C
storage temp. 
-20°C
solubility 
DMF:25.0(Max Conc. mg/mL);77.27(Max Conc. mM)
DMSO:25.0(Max Conc. mg/mL);77.27(Max Conc. mM)
Ethanol:50.0(Max Conc. mg/mL);154.55(Max Conc. mM)
form 
ethanol solution
pka
14.49±0.10(Predicted)
color 
Light yellow to light brown
Stability:
Light Sensitive, Temperature Sensitive
LogP
6.003 (est)
EPA Substance Registry System
9,12-Octadecadienamide, N-(2-hydroxyethyl)-, (9Z,12Z)- (68171-52-8)
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Safety

Hazard Codes 
F,Xi
Risk Statements 
11-36/37/38
Safety Statements 
16-26-36
RIDADR 
UN 1170 3/PG 2
WGK Germany 
1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
L1164
Product name
Linoleyl ethanolamide
Purity
≥98%, ethanol solution
Packaging
10mg
Price
$378
Updated
2025/07/31
Cayman Chemical
Product number
90155
Product name
Linoleoyl Ethanolamide
Purity
≥98%
Packaging
5mg
Price
$62
Updated
2024/03/01
Cayman Chemical
Product number
90155
Product name
Linoleoyl Ethanolamide
Purity
≥98%
Packaging
10mg
Price
$115
Updated
2024/03/01
Cayman Chemical
Product number
90155
Product name
Linoleoyl Ethanolamide
Purity
≥98%
Packaging
50mg
Price
$477
Updated
2024/03/01
Cayman Chemical
Product number
90155
Product name
Linoleoyl Ethanolamide
Purity
≥98%
Packaging
100mg
Price
$834
Updated
2024/03/01
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LINOLEOYLETHANOLAMIDE Chemical Properties,Usage,Production

Uses

N-Linoleoylethanolamine reduces lipopolysaccharide-induced inflammation in macrophages and reduces inflammation in ameliorates 2,4-dinitrofluorobenzene-induced contact dermatitis. N-Linoleoylethanolamine inhibits NF-κB signaling and may be used as a therapeutic agent against contact dermatitis.Linoleoyl ethanolamide is an endocannabinoid detected in porcine brain.

Definition

ChEBI: An N-(long-chain-acyl)ethanolamine that is the ethanolamide of linoleic acid.

Biochem/physiol Actions

A structural analogue of the endogenous cannabinoid receptor ligand anandamide.

in vivo

Linoleoyl ethanolamide (0.1 mg-0.2 mg; challenged by painting the inner and outer surfaces of both sides of their ears) suppresses DNFB-induced ear swelling in BALB/c mice[3].

LINOLEOYLETHANOLAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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68171-52-8, LINOLEOYLETHANOLAMIDERelated Search:


  • N-(2-HYDROXYETHYL)-9Z, 12Z-OCTADECADIENAMIDE
  • ODNHETOH
  • LEA
  • n-(2-hydroxyethyl)-,(z,z)-12-octadecadienamide
  • (9Z,12Z)-N-(2-hydroxyethyl)octadeca-9,12-dien-1-amide
  • 9,12-Octadecadienamide, N-(2-hydroxyethyl)-, (9Z,12Z)-
  • Linoleic ethanolamine
  • (9Z,12Z)-N-(2-Hydroxyethyl)-9,12-octadecadienamide
  • (9Z,12Z)-N-(2-Hydroxyethyl)-9,12-octadecadienoic acidamide
  • (9Z,12Z)-OCTADECA-9,12-DIENOLYLETHANOLAMIDE
  • LINOLEOYLETHANOLAMIDE
  • LINOLEYLETHANOLAMIDE
  • 9,12-Octadecadienamide, N-(2-hydroxyethyl)-
  • Einecs 269-029-6
  • Linoleic ethanolamide
  • Linoleoyl monoethanolamide
  • Monoethanolamine linoleic acid amide
  • N-lineleoyl Ethanolamide (LEA)
  • Anandamide (18:2,n6)
  • (9Z,12Z)-N-(2-hydroxyethyl)octadeca-9,12-dienamide
  • food,intake,Cannabinoid Receptor,feeding,Linoleic acid monoethanolamide,anandamide,post-meal,prolongation,Linoleoyl Ethanolamide,Inhibitor,inhibit,coupled,protein
  • Linoleoyl Ethanolamide, 10 mM in DMSO
  • 68171-52-8
  • Cannabinoids
  • Neurobiology
  • Pharmacologicals