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Endoxifen

Product Name
Endoxifen
CAS No.
112093-28-4
Chemical Name
Endoxifen
Synonyms
Avacopan;Endoxifen;Endoxifen(Z);(Z)-Endoxifen;Endoxifen (Z-isomer);salt CAS1032008-74-4;Tamoxifen Impurity 15;Endoxifen HCl Endoxifen Z-isomer;(Z)-4-Hydroxy-N-desmethyl Tamoxifen;Endoxifen Z-isomer (contains 3% E isomer))
CBNumber
CB31872472
Molecular Formula
C25H27NO2
Formula Weight
373.49
MOL File
112093-28-4.mol
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Endoxifen Property

Melting point:
127-129°C
Boiling point:
519.3±50.0 °C(Predicted)
Density 
1.099±0.06 g/cm3(Predicted)
storage temp. 
Amber Vial, -86°C Freezer, Under Inert Atmosphere
solubility 
DMSO : 50 mg/mL (133.87 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form 
Powder
pka
10.36±0.15(Predicted)
Stability:
Light Sensitive, Temperature Sensitive
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H361Suspected of damaging fertility or the unborn child

H372Causes damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

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N-Bromosuccinimide Price

Tocris
Product number
3705
Product name
Endoxifen
Purity
≥98%(HPLC)
Packaging
10
Price
$221
Updated
2021/12/16
Tocris
Product number
3705
Product name
Endoxifen
Purity
≥98%(HPLC)
Packaging
50
Price
$909
Updated
2021/12/16
Usbiological
Product number
255247
Product name
Endoxifen
Packaging
10mg
Price
$480
Updated
2021/12/16
TRC
Product number
H938500
Product name
(Z)-4-Hydroxy-N-desmethylTamoxifen(containsupto10%Eisomer)
Packaging
0.5mg
Price
$180
Updated
2021/12/16
ApexBio Technology
Product number
B7481
Product name
Endoxifen
Packaging
10mg
Price
$75
Updated
2021/12/16
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Endoxifen Chemical Properties,Usage,Production

Chemical Properties

Off-White to Pink Solid

Uses

A novel active metabolite of the anti-cancer drug Tamoxifen. It showed potent ER binding property, blocked estrogen stimulated growth of breast cancer cell and half maximal inhibition of estrogen responsive gene expression in ER pos. human breast ca

Uses

A novel active metabolite of the anti-cancer drug Tamoxifen (T006000). It showed potent ER binding property, blocked estrogen stimulated growth of breast cancer cell and half maximal inhibition of estrogen responsive gene expression in ER pos. human breast cancer cell line.

Definition

ChEBI: 4-Hydroxy-N-desmethyltamoxifen is a stilbenoid.

Endoxifen Preparation Products And Raw materials

Raw materials

Preparation Products

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Endoxifen Suppliers

Canada 1 China 77 India 3 United Kingdom 3 United States 12 Global 96
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View Lastest Price from Endoxifen manufacturers

Career Henan Chemical Co
Product
Endoxifen 112093-28-4
Price
US $3.00/KG
Min. Order
1KG
Purity
90%-99.9%
Supply Ability
10kg
Release date
2019-07-04

112093-28-4, EndoxifenRelated Search:

Endoxifen HCl Tamoxifen Impurity 3 4-Benzyloxy β-Hydroxy TaMoxifen TaMoxifen DiMer 1-(4-(2-Dimethylamino)-2-ethoxyphenyl butanone N-Desmethyl-4-hydroxy Tamoxifen β-D-Glucuronide (E/Z Mixture) 4Hydroxy Tamoxifen Tamoxifen EP Impurity D (E)-4-Alloxycarboxyl Tamoxifen desdimethyltamoxifen TAMOXIFEN-N-OXIDE Droloxifene (E)-4-Acetoxy Tamoxifen N-Desmethyl Tamoxifen Methanethiosulfonate 2-[4-[(E)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethyl-ethanamine alpha-[4-[2-(dimethylamino)ethoxy]phenyl]-beta-ethyl-alpha-phenylphenethyl alcohol (E)-4-Hydroxy-N-desmethyl Tamoxifen 4-HYDROXYTAMOXIFEN

  • (Z)-4-Hydroxy-N-desmethyl Tamoxifen
  • 4-[(1Z)-1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol
  • Endoxifen
  • Phenol, 4-[(1Z)-1-[4-[2-(MethylaMino)ethoxy]phenyl]-2-phenyl-1-butenyl]-
  • (Z)-4-Hydroxy-N-desmethyl Tamoxifen (contains up to 10% E isomer) see D292043
  • (Z)-4-Hydroxy-N-desmethyl Tamoxifen (contains up to 10% E isomer)
  • (Z)-4-Hydroxy-N-DesMethyl TaMoxifen (Endoxifen)
  • (Z)-Endoxifen
  • Endoxifen (Z-isomer)
  • Avacopan
  • 4-[(1Z)-1-{4-[2-(methylamino)ethoxy]phenyl}-2-phenylbut-1-en-1-yl]phenol
  • (Z)-4-Hydroxy-N-desmethyl Tamoxifen (contains 3% E isomer)
  • Endoxifen(Z)
  • salt CAS1032008-74-4
  • (Z)-4-Hydroxy-N-desmethyl Tamoxifen (mixture of isomers)
  • 4-[(Z)-1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol
  • (E/Z)-4-[1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-phenol
  • (Z)-4-(1-(4-(2-(methylamino)ethoxy)phenyl)-2-phenylbut-1-en-1-yl)phenol
  • Endoxifen Z-isomer (contains 3% E isomer))
  • Phenol, 4-[(1Z)-1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-
  • Tamoxifen Citrate Impurity 17((Z)-4-Hydroxy-N-Desmethyl Tamoxifen)
  • Endoxifen HCl Endoxifen Z-isomer
  • Tamoxifen Impurity 15
  • Potassium Channel,Endoxifen (Z-isomer),Endoxifen (Zisomer),Endoxifen (Z isomer),Inhibitor,KcsA,inhibit,Estrogen Receptor/ERR
  • 112093-28-4
  • Inhibitors
  • Aromatics, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
  • Aromatics
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals