ChemicalBook > CAS DataBase List > 4Hydroxy Tamoxifen
4Hydroxy Tamoxifen
- Product Name
- 4Hydroxy Tamoxifen
- CAS No.
- 82413-23-8
- Chemical Name
- 4Hydroxy Tamoxifen
- Synonyms
- 4’-hydroxy Tamoxifen;4'-Hydroxy TaMoxifen (contains up to 10% E isoMer);Tamoxifen Citrate Impurity 13 (4'-Hydroxytamoxifen);4-[(1Z)-1-[[4-[2-(Dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]phenol;Phenol, 4-[(1Z)-1-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]-
- CBNumber
- CB41175806
- Molecular Formula
- C26H29NO2
- Formula Weight
- 387.51
- MOL File
- 82413-23-8.mol
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4Hydroxy Tamoxifen Property
- Melting point:
- 150-153°C
- Boiling point:
- 514.4±50.0 °C(Predicted)
- Density
- 1.092±0.06 g/cm3(Predicted)
- storage temp.
- Amber Vial, -20°C Freezer, Under Inert Atmosphere
- solubility
- Chloroform (Slightly), Dichloromethane, Methanol (Slightly)
- form
- Solid
- pka
- 10.32±0.15(Predicted)
- color
- White to Off-White
- Stability:
- Light Sensitive
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 19519
- Product name
- 4’-hydroxy Tamoxifen
- Purity
- ≥98% (may contain up to 10% of the (E) isomer)
- Packaging
- 1mg
- Price
- $166
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 19519
- Product name
- 4’-hydroxy Tamoxifen
- Purity
- ≥98% (may contain up to 10% of the (E) isomer)
- Packaging
- 5mg
- Price
- $513
- Updated
- 2024/03/01
TRC
- Product number
- H954730
- Product name
- 4’-HydroxyTamoxifen(containsupto10%Eisomer)
- Packaging
- 25mg
- Price
- $1695
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- C4624
- Product name
- 4’-hydroxyTamoxifen
- Packaging
- 1mg
- Price
- $187
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- C4624
- Product name
- 4’-hydroxyTamoxifen
- Packaging
- 5mg
- Price
- $584
- Updated
- 2021/12/16
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4Hydroxy Tamoxifen Chemical Properties,Usage,Production
Description
4’-hydroxy Tamoxifen is one of five main phase I metabolites of tamoxifen , a well-known estrogen receptor antagonist in breast but partial estrogen receptor agonist in endometrium. 4’-hydroxy Tamoxifen is a product of cytochrome P450 (CYP)2D6 and CYP2B6 activity. With the addition of a hydroxyl group, 4’-hydroxy tamoxifen has been shown to have a higher affinity for estrogen receptors compared to tamoxifen. At 10-100 μM, 4’-hydroxy tamoxifen is cytotoxic, in a non-apoptotic manner, to HEC-1B and HEC-1A human endometrial adenocarcinoma cell lines.
Chemical Properties
White Solid
Uses
A metabolite of Tamoxifen (T006000).
4Hydroxy Tamoxifen Preparation Products And Raw materials
Raw materials
Preparation Products
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82413-23-8, 4Hydroxy TamoxifenRelated Search:
N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture)
Tamoxifen Impurity 3
4-Benzyloxy β-Hydroxy TaMoxifen
TaMoxifen DiMer
1-(4-(2-Dimethylamino)-2-ethoxyphenyl butanone
N-Desmethyl-4-hydroxy Tamoxifen β-D-Glucuronide
(E/Z Mixture)
Tamoxifen EP Impurity D
(E)-4-Alloxycarboxyl Tamoxifen
Endoxifen
desdimethyltamoxifen
TAMOXIFEN-N-OXIDE
Droloxifene
(E)-4-Acetoxy Tamoxifen
N-Desmethyl Tamoxifen Methanethiosulfonate
2-[4-[(E)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethyl-ethanamine
alpha-[4-[2-(dimethylamino)ethoxy]phenyl]-beta-ethyl-alpha-phenylphenethyl alcohol
(E)-4-Hydroxy-N-desmethyl Tamoxifen
(E/Z)-Tamoxifen