ChemicalBook > CAS DataBase List > 4Hydroxy Tamoxifen

4Hydroxy Tamoxifen

Product Name
4Hydroxy Tamoxifen
CAS No.
82413-23-8
Chemical Name
4Hydroxy Tamoxifen
Synonyms
4’-hydroxy Tamoxifen;4'-Hydroxy TaMoxifen (contains up to 10% E isoMer);Tamoxifen Citrate Impurity 13 (4'-Hydroxytamoxifen);4-[(1Z)-1-[[4-[2-(Dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]phenol;Phenol, 4-[(1Z)-1-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]-
CBNumber
CB41175806
Molecular Formula
C26H29NO2
Formula Weight
387.51
MOL File
82413-23-8.mol
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4Hydroxy Tamoxifen Property

Melting point:
150-153°C
Boiling point:
514.4±50.0 °C(Predicted)
Density 
1.092±0.06 g/cm3(Predicted)
storage temp. 
Amber Vial, -20°C Freezer, Under Inert Atmosphere
solubility 
Chloroform (Slightly), Dichloromethane, Methanol (Slightly)
form 
Solid
pka
10.32±0.15(Predicted)
color 
White to Off-White
Stability:
Light Sensitive
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
19519
Product name
4’-hydroxy Tamoxifen
Purity
≥98% (may contain up to 10% of the (E) isomer)
Packaging
1mg
Price
$166
Updated
2024/03/01
Cayman Chemical
Product number
19519
Product name
4’-hydroxy Tamoxifen
Purity
≥98% (may contain up to 10% of the (E) isomer)
Packaging
5mg
Price
$513
Updated
2024/03/01
TRC
Product number
H954730
Product name
4’-HydroxyTamoxifen(containsupto10%Eisomer)
Packaging
25mg
Price
$1695
Updated
2021/12/16
ApexBio Technology
Product number
C4624
Product name
4’-hydroxyTamoxifen
Packaging
1mg
Price
$187
Updated
2021/12/16
ApexBio Technology
Product number
C4624
Product name
4’-hydroxyTamoxifen
Packaging
5mg
Price
$584
Updated
2021/12/16
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4Hydroxy Tamoxifen Chemical Properties,Usage,Production

Description

4’-hydroxy Tamoxifen is one of five main phase I metabolites of tamoxifen , a well-known estrogen receptor antagonist in breast but partial estrogen receptor agonist in endometrium. 4’-hydroxy Tamoxifen is a product of cytochrome P450 (CYP)2D6 and CYP2B6 activity. With the addition of a hydroxyl group, 4’-hydroxy tamoxifen has been shown to have a higher affinity for estrogen receptors compared to tamoxifen. At 10-100 μM, 4’-hydroxy tamoxifen is cytotoxic, in a non-apoptotic manner, to HEC-1B and HEC-1A human endometrial adenocarcinoma cell lines.

Chemical Properties

White Solid

Uses

A metabolite of Tamoxifen (T006000).

4Hydroxy Tamoxifen Preparation Products And Raw materials

Raw materials

Preparation Products

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4Hydroxy Tamoxifen Suppliers

Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Fax
+86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2208
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14055
Advantage
65
Clearsynth Labs Limited
Tel
+91-22-26355700
Fax
+91-22-26355701
Email
info@clearsynth.com
Country
India
ProdList
9679
Advantage
58
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
56902
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32063
Advantage
58
Guangzhou Dreampharm Biotechnology Co., Ltd.
Tel
020-36607679 17825480238
Fax
QQ 3008233717
Email
3008233717@qq.com
Country
China
ProdList
9919
Advantage
12
Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28172
Advantage
58

82413-23-8, 4Hydroxy TamoxifenRelated Search:


  • 4-[(1Z)-1-[[4-[2-(Dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]phenol
  • 4'-Hydroxy TaMoxifen (contains up to 10% E isoMer)
  • Phenol, 4-[(1Z)-1-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]-
  • Tamoxifen Citrate Impurity 13 (4'-Hydroxytamoxifen)
  • 4’-hydroxy Tamoxifen
  • 82413-23-8
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals