ChemicalBook > CAS DataBase List > 4Hydroxy Tamoxifen

4Hydroxy Tamoxifen

Product Name
4Hydroxy Tamoxifen
CAS No.
82413-23-8
Chemical Name
4Hydroxy Tamoxifen
Synonyms
4’-hydroxy Tamoxifen;4'-Hydroxy TaMoxifen (contains up to 10% E isoMer);Tamoxifen Citrate Impurity 13 (4'-Hydroxytamoxifen);4-[(1Z)-1-[[4-[2-(Dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]phenol;Phenol, 4-[(1Z)-1-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]-
CBNumber
CB41175806
Molecular Formula
C26H29NO2
Formula Weight
387.51
MOL File
82413-23-8.mol
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4Hydroxy Tamoxifen Property

Melting point:
150-153°C
Boiling point:
514.4±50.0 °C(Predicted)
Density 
1.092±0.06 g/cm3(Predicted)
storage temp. 
Amber Vial, -20°C Freezer, Under Inert Atmosphere
solubility 
Chloroform (Slightly), Dichloromethane, Methanol (Slightly)
form 
Solid
pka
10.32±0.15(Predicted)
color 
White to Off-White
Stability:
Light Sensitive
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
19519
Product name
4’-hydroxy Tamoxifen
Purity
≥98% (may contain up to 10% of the (E) isomer)
Packaging
1mg
Price
$166
Updated
2024/03/01
Cayman Chemical
Product number
19519
Product name
4’-hydroxy Tamoxifen
Purity
≥98% (may contain up to 10% of the (E) isomer)
Packaging
5mg
Price
$513
Updated
2024/03/01
TRC
Product number
H954730
Product name
4’-HydroxyTamoxifen(containsupto10%Eisomer)
Packaging
25mg
Price
$1695
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
MTB0001871
Product name
4'-HYDROXY TAMOXIFEN
Purity
95.00%
Packaging
25MG
Price
$2194.5
Updated
2021/12/16
ApexBio Technology
Product number
C4624
Product name
4’-hydroxyTamoxifen
Packaging
1mg
Price
$187
Updated
2021/12/16
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4Hydroxy Tamoxifen Chemical Properties,Usage,Production

Description

4’-hydroxy Tamoxifen is one of five main phase I metabolites of tamoxifen , a well-known estrogen receptor antagonist in breast but partial estrogen receptor agonist in endometrium. 4’-hydroxy Tamoxifen is a product of cytochrome P450 (CYP)2D6 and CYP2B6 activity. With the addition of a hydroxyl group, 4’-hydroxy tamoxifen has been shown to have a higher affinity for estrogen receptors compared to tamoxifen. At 10-100 μM, 4’-hydroxy tamoxifen is cytotoxic, in a non-apoptotic manner, to HEC-1B and HEC-1A human endometrial adenocarcinoma cell lines.

Chemical Properties

White Solid

Uses

A metabolite of Tamoxifen (T006000).

4Hydroxy Tamoxifen Preparation Products And Raw materials

Raw materials

Preparation Products

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4Hydroxy Tamoxifen Suppliers

Canada 1 China 18 India 1 United States 5 Global 25
Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
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+86-21-57758967
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sales@boylechem.com
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China
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J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
Fax
86-10-82849933
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jkinfo@jkchemical.com
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China
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96815
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Chemsky（shanghai）International Co.,Ltd.
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021-50135380
Email
shchemsky@sina.com
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China
ProdList
32344
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50
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 13028896684
Email
sales@rrkchem.com
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China
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56056
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58
Guangzhou Dreampharm Biotechnology Co., Ltd.
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020-36607679 17825480238
Fax
QQ 3008233717
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3008233717@qq.com
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China
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9843
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12
Hubei Jusheng Technology Co.,Ltd.
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18871490254
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027-59599243
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linda@hubeijusheng.com
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CHINA
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28180
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58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767
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QQ 3610331285
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sales@chemegen.com
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China
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11289
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MedBioPharmaceutical Technology Inc
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021-69568360 18916172912
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order@med-bio.cn
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China
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8141
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Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
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China
ProdList
44941
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58
Shanghai YuZn Pharm. Technology Co.,Ltd.
Tel
15921286451; 15921286451
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2010681527@qq.com
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China
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58
Shenzhen Excellent Biomedical Technology Co., Ltd.
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18318671572
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2850803126@qq.com
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China
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4993
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58
Shanghai Yifei Biotechnology Co. , Ltd.
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021-65675885 18964387627
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customer_service@efebio.com
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China
ProdList
8740
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58
TargetMol Chemicals Inc.
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15002134094
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marketing@targetmol.com
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China
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24246
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Shenzhen Excellent Biomedical Technology Co.,Ltd.
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+86-0755-26050679 +86-15915472436
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sale@ex-biotech.cn
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China
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Shanghai Hao Zhun Biological Technology Co., Ltd.
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info@zzsrm.com
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CHINA
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Shanghai Yubo Biotechnology Co., Ltd.
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344843571@qq.com
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CHINA
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6322
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Shanghai Ziqi Biological Technology Co., Ltd.
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--
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2453006496@qq.com
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CHINA
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6192
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58
Absin Bioscience Inc.
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--
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--
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chenjw@absin.cn
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CHINA
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6661
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58

82413-23-8, 4Hydroxy TamoxifenRelated Search:

N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture) Tamoxifen Impurity 3 4-Benzyloxy β-Hydroxy TaMoxifen TaMoxifen DiMer 1-(4-(2-Dimethylamino)-2-ethoxyphenyl butanone N-Desmethyl-4-hydroxy Tamoxifen β-D-Glucuronide (E/Z Mixture) Tamoxifen EP Impurity D (E)-4-Alloxycarboxyl Tamoxifen Endoxifen desdimethyltamoxifen TAMOXIFEN-N-OXIDE Droloxifene (E)-4-Acetoxy Tamoxifen N-Desmethyl Tamoxifen Methanethiosulfonate 2-[4-[(E)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethyl-ethanamine alpha-[4-[2-(dimethylamino)ethoxy]phenyl]-beta-ethyl-alpha-phenylphenethyl alcohol (E)-4-Hydroxy-N-desmethyl Tamoxifen (E/Z)-Tamoxifen

  • 4-[(1Z)-1-[[4-[2-(Dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]phenol
  • 4'-Hydroxy TaMoxifen (contains up to 10% E isoMer)
  • Phenol, 4-[(1Z)-1-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]-
  • Tamoxifen Citrate Impurity 13 (4'-Hydroxytamoxifen)
  • 4’-hydroxy Tamoxifen
  • 82413-23-8
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals