4Hydroxy Tamoxifen

Product Name: 4Hydroxy Tamoxifen
CAS No.: 82413-23-8
Chemical Name: 4Hydroxy Tamoxifen
Synonyms: 4’-hydroxy Tamoxifen;4'-Hydroxy TaMoxifen (contains up to 10% E isoMer);Tamoxifen Citrate Impurity 13 (4'-Hydroxytamoxifen);4-[(1Z)-1-[[4-[2-(Dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]phenol;Phenol, 4-[(1Z)-1-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]-
CBNumber: CB41175806
Molecular Formula: C26H29NO2
Formula Weight: 387.51
MOL File: 82413-23-8.mol

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4Hydroxy Tamoxifen Property

Melting point:: 150-153°C
Boiling point:: 514.4±50.0 °C(Predicted)
Density: 1.092±0.06 g/cm3(Predicted)
storage temp.: Amber Vial, -20°C Freezer, Under Inert Atmosphere
solubility: Chloroform (Slightly), Dichloromethane, Methanol (Slightly)
form: Solid
pka: 10.32±0.15(Predicted)
color: White to Off-White
Stability:: Light Sensitive

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 19519
Product name: 4’-hydroxy Tamoxifen
Purity: ≥98% (may contain up to 10% of the (E) isomer)
Packaging: 1mg
Price: $166
Updated: 2024/03/01

Cayman Chemical

Product number: 19519
Product name: 4’-hydroxy Tamoxifen
Purity: ≥98% (may contain up to 10% of the (E) isomer)
Packaging: 5mg
Price: $513
Updated: 2024/03/01

TRC

Product number: H954730
Product name: 4’-HydroxyTamoxifen(containsupto10%Eisomer)
Packaging: 25mg
Price: $1695
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: MTB0001871
Product name: 4'-HYDROXY TAMOXIFEN
Purity: 95.00%
Packaging: 25MG
Price: $2194.5
Updated: 2021/12/16

ApexBio Technology

Product number: C4624
Product name: 4’-hydroxyTamoxifen
Packaging: 1mg
Price: $187
Updated: 2021/12/16

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4Hydroxy Tamoxifen Chemical Properties,Usage,Production

Description

4’-hydroxy Tamoxifen is one of five main phase I metabolites of tamoxifen , a well-known estrogen receptor antagonist in breast but partial estrogen receptor agonist in endometrium. 4’-hydroxy Tamoxifen is a product of cytochrome P450 (CYP)2D6 and CYP2B6 activity. With the addition of a hydroxyl group, 4’-hydroxy tamoxifen has been shown to have a higher affinity for estrogen receptors compared to tamoxifen. At 10-100 μM, 4’-hydroxy tamoxifen is cytotoxic, in a non-apoptotic manner, to HEC-1B and HEC-1A human endometrial adenocarcinoma cell lines.

Chemical Properties

White Solid

Uses

A metabolite of Tamoxifen (T006000).

4Hydroxy Tamoxifen Preparation Products And Raw materials

Raw materials

Preparation Products

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4Hydroxy Tamoxifen Suppliers

Canada 1 China 18 India 1 United States 5 Global 25

Clearsynth Labs Limited

Tel: +91-22-26355700
Fax: +91-22-26355701
Email: info@clearsynth.com
Country: India
ProdList: 9679
Advantage: 58

82413-23-8, 4Hydroxy TamoxifenRelated Search:

N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture) Tamoxifen Impurity 3 4-Benzyloxy β-Hydroxy TaMoxifen TaMoxifen DiMer 1-(4-(2-Dimethylamino)-2-ethoxyphenyl butanone N-Desmethyl-4-hydroxy Tamoxifen β-D-Glucuronide (E/Z Mixture) Tamoxifen EP Impurity D (E)-4-Alloxycarboxyl Tamoxifen Endoxifen desdimethyltamoxifen TAMOXIFEN-N-OXIDE Droloxifene (E)-4-Acetoxy Tamoxifen N-Desmethyl Tamoxifen Methanethiosulfonate 2-[4-[(E)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethyl-ethanamine alpha-[4-[2-(dimethylamino)ethoxy]phenyl]-beta-ethyl-alpha-phenylphenethyl alcohol (E)-4-Hydroxy-N-desmethyl Tamoxifen (E/Z)-Tamoxifen

4-[(1Z)-1-[[4-[2-(Dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]phenol

4'-Hydroxy TaMoxifen (contains up to 10% E isoMer)

Phenol, 4-[(1Z)-1-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]-

Tamoxifen Citrate Impurity 13 (4'-Hydroxytamoxifen)

4’-hydroxy Tamoxifen

82413-23-8

Intermediates & Fine Chemicals

Metabolites & Impurities

Pharmaceuticals