ChemicalBook > CAS DataBase List > 4Hydroxy Tamoxifen

4Hydroxy Tamoxifen

Product Name
4Hydroxy Tamoxifen
CAS No.
82413-23-8
Chemical Name
4Hydroxy Tamoxifen
Synonyms
4’-hydroxy Tamoxifen;4'-Hydroxy TaMoxifen (contains up to 10% E isoMer);Tamoxifen Citrate Impurity 13 (4'-Hydroxytamoxifen);4-[(1Z)-1-[[4-[2-(Dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]phenol;Phenol, 4-[(1Z)-1-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]-
CBNumber
CB41175806
Molecular Formula
C26H29NO2
Formula Weight
387.51
MOL File
82413-23-8.mol
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4Hydroxy Tamoxifen Property

Melting point:
150-153°C
Boiling point:
514.4±50.0 °C(Predicted)
Density 
1.092±0.06 g/cm3(Predicted)
storage temp. 
Amber Vial, -20°C Freezer, Under Inert Atmosphere
solubility 
Chloroform (Slightly), Dichloromethane, Methanol (Slightly)
form 
Solid
pka
10.32±0.15(Predicted)
color 
White to Off-White
Stability:
Light Sensitive
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
19519
Product name
4’-hydroxy Tamoxifen
Purity
≥98% (may contain up to 10% of the (E) isomer)
Packaging
1mg
Price
$166
Updated
2024/03/01
Cayman Chemical
Product number
19519
Product name
4’-hydroxy Tamoxifen
Purity
≥98% (may contain up to 10% of the (E) isomer)
Packaging
5mg
Price
$513
Updated
2024/03/01
TRC
Product number
H954730
Product name
4’-HydroxyTamoxifen(containsupto10%Eisomer)
Packaging
25mg
Price
$1695
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
MTB0001871
Product name
4'-HYDROXY TAMOXIFEN
Purity
95.00%
Packaging
25MG
Price
$2194.5
Updated
2021/12/16
ApexBio Technology
Product number
C4624
Product name
4’-hydroxyTamoxifen
Packaging
1mg
Price
$187
Updated
2021/12/16
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4Hydroxy Tamoxifen Chemical Properties,Usage,Production

Description

4’-hydroxy Tamoxifen is one of five main phase I metabolites of tamoxifen , a well-known estrogen receptor antagonist in breast but partial estrogen receptor agonist in endometrium. 4’-hydroxy Tamoxifen is a product of cytochrome P450 (CYP)2D6 and CYP2B6 activity. With the addition of a hydroxyl group, 4’-hydroxy tamoxifen has been shown to have a higher affinity for estrogen receptors compared to tamoxifen. At 10-100 μM, 4’-hydroxy tamoxifen is cytotoxic, in a non-apoptotic manner, to HEC-1B and HEC-1A human endometrial adenocarcinoma cell lines.

Chemical Properties

White Solid

Uses

A metabolite of Tamoxifen (T006000).

4Hydroxy Tamoxifen Preparation Products And Raw materials

Raw materials

Preparation Products

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4Hydroxy Tamoxifen Suppliers

Clearsynth Labs Limited
Tel
+91-22-26355700
Fax
+91-22-26355701
Email
info@clearsynth.com
Country
India
ProdList
9685
Advantage
58

82413-23-8, 4Hydroxy TamoxifenRelated Search:


  • 4-[(1Z)-1-[[4-[2-(Dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]phenol
  • 4'-Hydroxy TaMoxifen (contains up to 10% E isoMer)
  • Phenol, 4-[(1Z)-1-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]-
  • Tamoxifen Citrate Impurity 13 (4'-Hydroxytamoxifen)
  • 4’-hydroxy Tamoxifen
  • 82413-23-8
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals