ChemicalBook > CAS DataBase List > Succinylsulfathiazole

Succinylsulfathiazole

Product Name
Succinylsulfathiazole
CAS No.
116-43-8
Chemical Name
Succinylsulfathiazole
Synonyms
SST;rolsul;THIACYL;kaoxidin;KAOXIDINE;colistatin;sulfadigesin;SULFENTERONE;SST-PB3M-CPX;SST-PFB3-VME
CBNumber
CB3187922
Molecular Formula
C13H13N3O5S2
Formula Weight
355.39
MOL File
116-43-8.mol
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Succinylsulfathiazole Property

Melting point:
193.5°C
Density 
1.4807 (rough estimate)
refractive index 
1.6390 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
1 M NaOH: soluble50mg/mL
pka
pKa 4.5 (Uncertain)
form 
powder
color 
white to off-white
Water Solubility 
0.49g/L(38 ºC)
λmax
282nm(H2O (pH 3.3 - 5))(lit.)
Merck 
14,8877
BRN 
349989
CAS DataBase Reference
116-43-8(CAS DataBase Reference)
EPA Substance Registry System
Butanoic acid, 4-oxo-4-[[4-[(2-thiazolylamino)sulfonyl]phenyl]amino]- (116-43-8)
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Safety

Hazard Codes 
Xn
Risk Statements 
42/43
Safety Statements 
22-36/37-45
RIDADR 
3249
WGK Germany 
3
RTECS 
WM4767000
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29350090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S364843
Product name
N1-(2-THIAZOLYL)-N4-SUCCINOYLSULFANILAMIDE
Purity
Aldrich
Packaging
250mg
Price
$110
Updated
2024/03/01
TCI Chemical
Product number
S0991
Product name
Succinylsulfathiazole
Purity
>97.0%(HPLC)
Packaging
25g
Price
$50
Updated
2021/12/16
Usbiological
Product number
359043
Product name
Sst
Packaging
48Tests
Price
$588
Updated
2021/12/16
Usbiological
Product number
384508
Product name
SST
Packaging
96Tests
Price
$729
Updated
2021/12/16
Usbiological
Product number
384506
Product name
SST
Packaging
96Tests
Price
$729
Updated
2021/12/16
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Succinylsulfathiazole Chemical Properties,Usage,Production

Originator

Sulfasuxidine,MSD,US,1942

Uses

Succinylsulfathiazole is a sulfonamide antibiotic that was shown to inhibit bacteria that are responsible for folate production. Succinylsulfathiazole was used in various folate deficiency studies to block the synthesis of folic acid.

Uses

Succinylsulfathiazole is antibacterial

Definition

ChEBI: N-succinylsulfathiazole is a member of 1,3-thiazoles. It is functionally related to a sulfathiazole.

Manufacturing Process

3.92 g of succinic anhydride was added to a boiling suspension of 10 g of 2- sulfanilamidothiazole in 100 cc of alcohol. The mixture was then refluxed for five minutes after the addition was complete at which time all of the solids were in solution. The solution was then cooled and diluted with an equal volume of water. The white solid precipitate which formed was filtered and recrystallized from dilute alcohol, yielding 2-N4-succinylsulfanilamidothiazole, melting at 184°C to 186°C.

Therapeutic Function

Antibacterial (intestinal)

Succinylsulfathiazole Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Succinylsulfathiazole manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Succinylsulfathiazole 116-43-8
Price
US $65.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000kg/week
Release date
2024-05-27
airuikechemical co., ltd.
Product
Succinylsulfathiazole (SST) 116-43-8
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.9%
Supply Ability
200tons
Release date
2024-04-08
Qingdao RENAS Polymer Material Co., Ltd.
Product
Succinylsulfathiazole 116-43-8
Price
US $0.00/kg
Min. Order
20kg
Purity
99%
Supply Ability
20 tons
Release date
2024-10-15

116-43-8, SuccinylsulfathiazoleRelated Search:

Sulfanilamide Sulfathiazole N4-SUCCINYLSULFATHIAZOLE MONOHYDRATE N-METHYLSUCCINAMIC ACID 2-CHLOROMETHYL-3,4-DIMETHOXY PYRIDINE HYDROCHLORIDE 4-AMINO-N-METHYL-BENZENESULFONAMIDE 4-Acetamidobenzenesulfonamide 4-Acetamidothiophenol sulfasuccinamide 4-Anilino-4-oxobutanoic Acid 4-ETHYLAMINO-BENZENESULFONAMIDE Succinylsulfathiazole 4'-(thiazol-2-ylsulphamoyl)acetanilide

  • colistatin
  • cremosuxidine
  • kaoxidin
  • KAOXIDINE
  • sulfasuccidin
  • sulfasuccidine
  • sulfasuccinil
  • sulfasuccithiazole
  • 4-(Succinylamino)-N-(2-thiazolyl)benzenesulfonamide
  • N4-Succinyl-N-(2-thiazolyl)sulfanilamide
  • Succinylsulfathiazole Hydrate
  • Butanoic acid, 4-oxo-4-[[4-[(2-thiazolylamino)sulfonyl]phenyl]amino]-
  • 2-(n(4)-succinylsulfanilamido)thiazole
  • 2-(N-SUCCINYLSULFANILAMIDO)THIAZOLE
  • 4’-(2-thiazolylsulfamoyl)-succinanilicaci
  • 4-oxo-4-((4-((2-thiazolylamino)sulfonyl)phenyl)amino)-butanoicaci
  • succinylsulphathiazole
  • sulfadigesin
  • Sulfadigestin
  • 4'-(2-THIAZOLYLSULFAMOYL)-SUCCINANILIC ACID
  • THIACYL
  • SUCCINYLSULFATHIAZOLE
  • SULFENTERONE
  • SULFASUXIDINE
  • SST
  • rolsul
  • p-2-thiazolylsulfamoylsuccinanilic acid
  • 4-(Succinylamino)-N-(2-thiazolyl)benzenesulfonamide N4-Succinyl-N-(2-thiazolyl)sulfanilamide
  • 4-oxo-4-((4-(N-(thiazol-2-yl)sulfaMoyl)phenyl)aMino)butanoic acid
  • N-succinylsulfathiazole
  • N1-(2-THIAZOLYL)-N4-SUCCINOYLSULFANILAMIDE
  • SST-PB3M-CPX
  • SST-PFB3-VME
  • APP-PS7-PCIE
  • Succinylsulfathiazole (SST)
  • Succinylsulfathiazole USP/EP/BP
  • C16985600 Succinylsulfathiazole
  • 116-43-8
  • C13H13N3O5S2
  • C13H13N3O5S2xH2O
  • Antibiotics A to Z
  • Antibiotics N-S
  • Antibiotics
  • BioChemical
  • SULFASUXIDINE
  • Antibacterial
  • Antibiotics
  • Antibiotics A to
  • Antibiotics N-SAntibiotics
  • Chemical Structure Class
  • Inhibits an EnzymeAntibiotics
  • Interferes with DNA SynthesisSpectrum of Activity
  • L - ZAntibiotics
  • Mechanism of Action
  • Sulfonamides
  • Antibiotics for Research and Experimental Use
  • Biochemistry
  • Sulfonamides (Antibiotics for Research and Experimental Use)