8-METHYLTHIOGUANOSINE

Product Name: 8-METHYLTHIOGUANOSINE
CAS No.: 2104-66-7
Chemical Name: 8-METHYLTHIOGUANOSINE
Synonyms: 8-METHYLTHIOGUANOSINE;Guanosine, 8-(methylthio)-
CBNumber: CB3198568
Molecular Formula: C11H15N5O5S
Formula Weight: 329.33
MOL File: Mol file

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8-METHYLTHIOGUANOSINE Property

Density: 2.12±0.1 g/cm3(Predicted)
pka: 9.17±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

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8-METHYLTHIOGUANOSINE Chemical Properties,Usage,Production

Uses

8-(Methylthio)guanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

References

[1] Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51. DOI:10.1073/pnas.0631696100

8-METHYLTHIOGUANOSINE Preparation Products And Raw materials

Raw materials

Preparation Products

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8-METHYLTHIOGUANOSINE Suppliers

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2104-66-7, 8-METHYLTHIOGUANOSINERelated Search:

8-methylguanosine Adenosine,8-(methylthio)- (7CI,8CI,9CI) 8-methyladenosine

8-METHYLTHIOGUANOSINE

Guanosine, 8-(methylthio)-

2104-66-7