METHYL 1-(DIPHENYLMETHYL)AZETIDINE-3-CARBOXYLATE
- Product Name
- METHYL 1-(DIPHENYLMETHYL)AZETIDINE-3-CARBOXYLATE
- CAS No.
- 53871-06-0
- Chemical Name
- METHYL 1-(DIPHENYLMETHYL)AZETIDINE-3-CARBOXYLATE
- Synonyms
- METHYL 1-BENZHYDRYLAZETIDINE-3-CARBOXYLATE;BUTTPARK 37\04-18;Methyl 1-diphenylMethyl-a...;Methyl 1-(diphenylmethyl)-3-azetidinecarboxylate;METHYL 1-(DIPHENYLMETHYL)AZETIDINE-3-CARBOXYLATE;N-BENZHYDRYLAZETIDINE-3-CARBOXYLIC ACID METHYL ESTER;1-BENZHYDRYL-AZETIDINE-3-CARBOXYLIC ACID METHYL ESTER;Methyl 1-diphenylmethyl-azetidine-3-carboxylate - [M1904];1-(Diphenylmethyl)azetidine-3-carboxylic acid methyl ester;3-AZETIDINECARBOXYLIC ACID, 1-(DIPHENYLMETHYL)-, METHYL ESTER
- CBNumber
- CB3199020
- Molecular Formula
- C18H19NO2
- Formula Weight
- 281.35
- MOL File
- 53871-06-0.mol
METHYL 1-(DIPHENYLMETHYL)AZETIDINE-3-CARBOXYLATE Property
- Melting point:
- 67-70°C
- Boiling point:
- 366℃
- Density
- 1.163
- Flash point:
- 122℃
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 6.41±0.10(Predicted)
- Appearance
- White to light brown Solid
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- M218793
- Product name
- Methyl1-(Diphenylmethyl)azetidine-3-carboxylate
- Packaging
- 500mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 4H23-1-3P
- Product name
- Methyl 1-(diphenylmethyl)azetidine-3-carboxylate
- Packaging
- 1g
- Price
- $38
- Updated
- 2021/12/16
- Product number
- M1904
- Product name
- Methyl1-diphenylmethyl-azetidine-3-carboxylate
- Purity
- 97.0%
- Packaging
- 5g
- Price
- $50
- Updated
- 2021/12/16
- Product number
- 4H23-1-3P
- Product name
- Methyl 1-(diphenylmethyl)azetidine-3-carboxylate
- Packaging
- 5G
- Price
- $58
- Updated
- 2021/12/16
- Product number
- CHM0078988
- Product name
- METHYL-1-(DIPHENYLMETHYL)AZETIDINE-3-CARBOXYLATE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $130.2
- Updated
- 2021/12/16
METHYL 1-(DIPHENYLMETHYL)AZETIDINE-3-CARBOXYLATE Chemical Properties,Usage,Production
Synthesis
36476-87-6
74-88-4
53871-06-0
GENERAL STEPS: Potassium carbonate (6.53 g, 47.2 mmol) and iodomethane (0.976 mL, 15.7 mmol) were sequentially added to a solution of N,N-dimethylformamide (45 mL) of 1-diphenylmethylazetidine-3-carboxylic acid (4.20 g, 15.7 mmol) and the reaction was stirred at room temperature for 20.5 hours. After completion of the reaction, the reaction mixture was slowly poured into ice water and extracted with ethyl acetate (3 × 50 mL). The organic layers were combined, washed with saturated saline (50 mL) and dried over anhydrous sodium sulfate. The solvent was removed by concentration under reduced pressure and the resulting crude product was purified by silica gel column chromatography (elution gradient: heptane/ethyl acetate = 5:1 to 3:1). The fraction containing the target compound was collected and concentrated under reduced pressure to give methyl 1-diphenylmethylazetidine-3-carboxylate (3.57 g, 80.8% yield) as yellow crystals.1H NMR (400 MHz, CDCl3) δ: 3.26 (m, 2H), 3.31 (m, 1H), 3.44 (m, 2H), 3.69 (s, 3H), 4.38 (s, 1H), 7.16-7.16-7.16 1H), 7.16-7.20 (m, 2H), 7.25-7.28 (m, 4H), 7.39-7.41 (m, 4H). ESI-MS m/z: 282 [M + H]+.
References
[1] Patent: US2008/214815, 2008, A1. Location in patent: Page/Page column 14
[2] Patent: EP1889836, 2008, A1. Location in patent: Page/Page column 80
METHYL 1-(DIPHENYLMETHYL)AZETIDINE-3-CARBOXYLATE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from METHYL 1-(DIPHENYLMETHYL)AZETIDINE-3-CARBOXYLATE manufacturers
- Product
- METHYL 1-(DIPHENYLMETHYL)AZETIDINE-3-CARBOXYLATE 53871-06-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kgs
- Release date
- 2020-02-13