2(5H)-Furanone
- Product Name
- 2(5H)-Furanone
- CAS No.
- 497-23-4
- Chemical Name
- 2(5H)-Furanone
- Synonyms
- FURANONE;FURAN-2(5H)-ONE;Butenolide;γ-Crotonolactone;2-Furanone;4-Hydroxy-2-butenoic acid gamma-lactone;CARMELAN;2-Butenolide;2H-furan-5-one;Crotonolactone
- CBNumber
- CB3201475
- Molecular Formula
- C4H4O2
- Formula Weight
- 84.07
- MOL File
- 497-23-4.mol
2(5H)-Furanone Property
- Melting point:
- 4-5 °C (lit.)
- Boiling point:
- 86-87 °C/12 mmHg (lit.)
- Density
- 1.185 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.469(lit.)
- FEMA
- 4138 | 4-HYDROXY-2-BUTENOIC ACID GAMMA-LACTONE
- Flash point:
- 214 °F
- storage temp.
- 2-8°C
- solubility
- Chloroform, Ethyl Acetate (Slightly)
- form
- Liquid
- color
- Clear colorless to pale yellow or amber
- Odor
- buttery
- Odor Type
- buttery
- Water Solubility
- Immiscible with water.
- JECFA Number
- 2000
- BRN
- 383585
- Stability:
- Moisture Sensitive
- InChIKey
- VIHAEDVKXSOUAT-UHFFFAOYSA-N
- LogP
- -0.600
- CAS DataBase Reference
- 497-23-4(CAS DataBase Reference)
- NIST Chemistry Reference
- 2(5H)-Furanone(497-23-4)
- EPA Substance Registry System
- 2(5H)-Furanone (497-23-4)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26
- WGK Germany
- 3
- RTECS
- LU3453000
- F
- 8-10
- Hazard Note
- Irritant
- HS Code
- 29322980
- Hazardous Substances Data
- 497-23-4(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 283754
- Product name
- 2(5H)-Furanone
- Purity
- 98%
- Packaging
- 1g
- Price
- $89.1
- Updated
- 2024/03/01
- Product number
- 283754
- Product name
- 2(5H)-Furanone
- Purity
- 98%
- Packaging
- 5g
- Price
- $350
- Updated
- 2024/03/01
- Product number
- C1078
- Product name
- gamma-Crotonolactone
- Purity
- >93.0%(GC)
- Packaging
- 5mL
- Price
- $50
- Updated
- 2024/03/01
- Product number
- C1078
- Product name
- gamma-Crotonolactone
- Purity
- >93.0%(GC)
- Packaging
- 25mL
- Price
- $180
- Updated
- 2024/03/01
- Product number
- L13142
- Product name
- 2(5H)-Furanone, 96%
- Packaging
- 1g
- Price
- $62.65
- Updated
- 2024/03/01
2(5H)-Furanone Chemical Properties,Usage,Production
Chemical Properties
Colorless to pale brown-yellow clear liquid
Chemical Properties
2(5H)-Furanone is light brown liquid
Occurrence
Reported found in coffee
Uses
2(5H)-Furanone is employed in the preparation of 5-substituted 2(5H) furanones (gamma-butenolides) catalyzed by bifunctional aminothiourea and aminosquaramide organocatalysts through direct aldol reaction with aromatic aldehydes. Further, it is used in the synthesis of lignans by Michael addition reactions. In addition to this, it is used in three-component Michael-Aldol reactions with an aldehyde and thiolate or carbanion.
Uses
2(5H)-Furanone is a heterocyclic organic compound that is used widely in the synthetic preparation of pharmaceutical goods.
Uses
2(5H)-Furanone is a versatile reagent used in Michael addition reactions1 for synthesis of lignans.2 Also employed in three-component Michael-Aldol reactions with an aldehyde anda thiolate3 or carbanion.4
Definition
2(5H)-Furanone is a mycotoxin that contains an α,β-unsaturated lactone moiety.
General Description
Chiral urea compounds catalyzed hetero-Michael addition reaction of 2(5H)-furanone (γ-crotonolactone) to pyrrolidine. The quorum sensing inhibition activity by 2(5H)-furanone was studied using bioindicator strains.
Hazard
Extremely toxic.
Purification Methods
Fractionally distil the lactone under reduced pressure. IR: (CCl4) 1784 and 1742 cm-1, UV no max above 205nm ( 1160 cm-1 M-1) and 1HR: (CCl3) : 2.15 (pair of triplets 1H), 3.85 (pair of triplets 1H) and 5.03 (triplet 2H). [Price & Judge Org Synth Coll Vol V 255 1973, Smith & Jones Can J Chem 37 2007, 2092 1959, Beilstein 17/9 V 112.]
2(5H)-Furanone Preparation Products And Raw materials
Raw materials
Preparation Products
2(5H)-Furanone Suppliers
- Tel
- 03-36680489
- Fax
- 03-3668-0520
- Sales-JP@TCIchemicals.com
- Country
- Japan
- ProdList
- 28398
- Advantage
- 80
View Lastest Price from 2(5H)-Furanone manufacturers
- Product
- 2(5H)-Furanone 497-23-4
- Price
- US $5.00-2.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-16
- Product
- 2(5H)-Furanone 497-23-4
- Price
- US $30.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100tons
- Release date
- 2022-10-25
- Product
- 2(5H)-Furanone 497-23-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-13