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Nonafluorobutanesulfonyl fluoride

Product Name
Nonafluorobutanesulfonyl fluoride
CAS No.
375-72-4
Chemical Name
Nonafluorobutanesulfonyl fluoride
Synonyms
PBSF;1,1,2,2,3,3,4,4,4-Nonafluorobutane-1-sulfonyl fluoride;PERFLUORO-1-BUTANESULFONYL FLUORIDE;FC-4;PERFLUOROBUTANESULFONYL FLUORIDE;Perfluoro n-butylsulfonyl fluoride;Nonafluorobutane-1-sulfonyl fluoride;Nonaflylfluoride;FX-4;50KGS/DRUM
CBNumber
CB3208090
Molecular Formula
C4F10O2S
Formula Weight
302.09
MOL File
375-72-4.mol
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Nonafluorobutanesulfonyl fluoride Property

Melting point:
-110°C
Boiling point:
64 °C (lit.)
Density 
1.682 g/mL at 25 °C (lit.)
vapor pressure 
16.665kPa at 20℃
refractive index 
n20/D 1.3(lit.)
Flash point:
65-66°C
storage temp. 
Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility 
Chloroform (Sparingly), Methanol (Sparingly)
form 
Liquid
color 
Colorless to yellow
Specific Gravity
1.682
Water Solubility 
Hydrolyses in water.
Sensitive 
Moisture Sensitive
BRN 
1813589
Stability:
Hygroscopic
InChIKey
LUYQYZLEHLTPBH-UHFFFAOYSA-N
CAS DataBase Reference
375-72-4(CAS DataBase Reference)
NIST Chemistry Reference
Nonafluorobutanesulfonyl fluoride(375-72-4)
EPA Substance Registry System
1-Butanesulfonyl fluoride, 1,1,2,2,3,3,4,4,4-nonafluoro- (375-72-4)
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Safety

Hazard Codes 
C
Risk Statements 
34
Safety Statements 
26-36/37/39-45-25
RIDADR 
UN 3265 8/PG 2
WGK Germany 
3
10-21
Hazard Note 
Corrosive
TSCA 
Yes
HazardClass 
8
PackingGroup 
II
HS Code 
29049090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
319732
Product name
Perfluoro-1-butanesulfonyl fluoride
Purity
96%
Packaging
25g
Price
$98.5
Updated
2024/03/01
Sigma-Aldrich
Product number
319732
Product name
Perfluoro-1-butanesulfonyl fluoride
Purity
96%
Packaging
100g
Price
$194
Updated
2024/03/01
TCI Chemical
Product number
P1098
Product name
Perfluoro-1-butanesulfonyl Fluoride
Purity
>93.0%(GC)
Packaging
25g
Price
$79
Updated
2024/03/01
TCI Chemical
Product number
P1098
Product name
Perfluoro-1-butanesulfonyl Fluoride
Purity
>93.0%(GC)
Packaging
250g
Price
$460
Updated
2024/03/01
Alfa Aesar
Product number
B21322
Product name
Nonafluorobutanesulfonyl fluoride, 90+%
Packaging
5g
Price
$24.65
Updated
2024/03/01
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Nonafluorobutanesulfonyl fluoride Chemical Properties,Usage,Production

Chemical Properties

Nonafluorobutanesulfonyl fluoride is a colorless, volatile liquid that is immiscible with water but soluble in common organic solvents. It is prepared by the electrochemical fluorination of sulfolane.

Uses

Nonafluorobutanesulfonyl fluoride can be used as a general-purpose diazotransfer reagent with high efficiency, wide substrate range, good shelf stability, relatively low cost, and easy purification. It is a favourable alternative to other commonly used diazotransfer reagents[1]. In addition, Nonafluorobutanesulfonyl fluoride was used in the formation of a new dehydrated glycosylation scheme. In contrast to the main classical glycosylation reactions, this scheme glycosylation reaction is carried out under mildly alkaline conditions. In the absence of an external acceptor, the glycosyl hemiacetal undergoes self-condensation, providing the corresponding symmetric 1,1'- disaccharide in high yield[2].

Uses

Benzynes were generated from o-(trimethylsilyl) phenols using nonafluorobutanesulfonyl fluoride (NfF) by a domino process.Nonafluorobutanesulfonyl fluoride (nonaflyl fluoride, C 4 F 9 SO 2 F, NfF) is the most widely used commercially available reagent for the synthesis of nonaflates.

storage

Store in amber colored bottles protected from light; for prolonged storage, PVC bottles are recommended.

References

[1] JOSE LUIS CHIARA; José R S. Synthesis of α-Diazo Carbonyl Compounds with the Shelf-Stable Diazo Transfer Reagent Nonafluorobutanesulfonyl Azide[J]. Advanced Synthesis & Catalysis, 2011. DOI:10.1002/adsc.201000846.
[2] YU TANG; Biao Y; D Prabhakar Reddy. A dehydrative glycosylation protocol mediated by nonafluorobutanesulfonyl fluoride (NfF)[J]. Tetrahedron, 2021. DOI:10.1016/j.tet.2020.131800.

Nonafluorobutanesulfonyl fluoride Preparation Products And Raw materials

Raw materials

Preparation Products

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Nonafluorobutanesulfonyl fluoride Suppliers

SHINWON CHEMTRADE CO., LTD
Tel
--
Fax
--
Email
info@shinwonchem.com
Country
South Korea
ProdList
231
Advantage
43
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View Lastest Price from Nonafluorobutanesulfonyl fluoride manufacturers

hebei hongtan Biotechnology Co., Ltd
Product
Nonafluorobutanesulfonyl fluoride 375-72-4
Price
US $50.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000
Release date
2024-03-22
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Perfluorobutanesulfonyl Fluoride / Nonafluorobutanesulfonyl Fluoride 375-72-4
Price
US $120.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-04-25
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Nonafluorobutane Sulfonyl fluoride 375-72-4
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-21

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