2-CHLORO-1-PIPERIDIN-1-YL-ETHANONE
- Product Name
- 2-CHLORO-1-PIPERIDIN-1-YL-ETHANONE
- CAS No.
- 1440-60-4
- Chemical Name
- 2-CHLORO-1-PIPERIDIN-1-YL-ETHANONE
- Synonyms
- LABOTEST-BB LT00000083;1-(CHLOROACETYL)PIPERIDINE;Pipridine, 1-chloroacetyl-;2-chloro-1-piperidino-ethanone;Piperidine, N-[2-chloroacetyl]-;2-CHLORO-1-PIPERIDINE ACETAMIDE;2-chloro-1-(1-piperidyl)ethanone;2-CHLORO-1-PIPERIDIN-1-YL-ETHANONE;2-Chloro-1-(1-piperidinyl)ethanone;2-Chloro-1-piperidine-1-yl-ethanone
- CBNumber
- CB3209820
- Molecular Formula
- C7H12ClNO
- Formula Weight
- 161.63
- MOL File
- 1440-60-4.mol
2-CHLORO-1-PIPERIDIN-1-YL-ETHANONE Property
- Boiling point:
- 85°C/0.08mm
- storage temp.
- Storage temp. 2-8°C
- form
- liquid
- color
- Yellow
- CAS DataBase Reference
- 1440-60-4(CAS DataBase Reference)
Safety
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- C380353
- Product name
- 2-Chloro-1-piperidin-1-yl-ethanone
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- C380353
- Product name
- 2-Chloro-1-piperidin-1-yl-ethanone
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FC133246
- Product name
- 1-(Chloroacetyl)piperidine
- Packaging
- 500mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 138408
- Product name
- 1-(Chloroacetyl)piperidine
- Purity
- 95%+
- Packaging
- 5g
- Price
- $323
- Updated
- 2021/12/16
- Product number
- FC133246
- Product name
- 1-(Chloroacetyl)piperidine
- Packaging
- 5G
- Price
- $358
- Updated
- 2021/12/16
2-CHLORO-1-PIPERIDIN-1-YL-ETHANONE Chemical Properties,Usage,Production
Synthesis
110-89-4
79-04-9
1440-60-4
GENERAL METHOD: Chloroacetyl chloride (3.70 mL, 46.45 mmol) was slowly added dropwise to a solution of hexahydropyridine (4.50 mL, 51.45 mmol) and triethylamine (7.90 mL, 56.68 mmol) in methylene chloride (80 mL) at 0°C. The reaction temperature was kept constant for 6 hours. After the dropwise addition was completed by keeping the reaction temperature at 0 °C, the reaction mixture was gradually warmed up to room temperature and stirred for 6 hours. After completion of the reaction, the reaction mixture was diluted with dichloromethane, washed with saturated sodium bicarbonate solution and brine sequentially, the organic phase was dried with anhydrous magnesium sulfate and filtered. The filtrate was concentrated under reduced pressure to give 2-chloro-1-(piperidin-1-yl)ethanone (7.55 g, 99% yield) as a light yellow liquid.
References
[1] Canadian Journal of Chemistry, 2004, vol. 82, # 5, p. 622 - 630
[2] Molecules, 2015, vol. 20, # 11, p. 19984 - 20013
[3] Synthetic Communications, 1998, vol. 28, # 22, p. 4257 - 4272
[4] Patent: WO2012/52843, 2012, A1. Location in patent: Page/Page column 73-74
[5] Chemistry - A European Journal, 2012, vol. 18, # 29, p. 8978 - 8986
2-CHLORO-1-PIPERIDIN-1-YL-ETHANONE Preparation Products And Raw materials
Raw materials
Preparation Products
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