Anti-G3BP1, Anti-GAP SH3 domain-binding protein, Anti-HDH-VIII, Anti-human DNA helicase VIII, Anti-Ras-GTPase-activating protein SH3-domain binding protein 1

Product Name
Anti-G3BP1, Anti-GAP SH3 domain-binding protein, Anti-HDH-VIII, Anti-human DNA helicase VIII, Anti-Ras-GTPase-activating protein SH3-domain binding protein 1
Chemical Name
Anti-G3BP1, Anti-GAP SH3 domain-binding protein, Anti-HDH-VIII, Anti-human DNA helicase VIII, Anti-Ras-GTPase-activating protein SH3-domain binding protein 1
Synonyms
Anti-G3BP1;Anti-HDH-VIII;Anti-human DNA helicase VIII;Anti-GAP SH3 domain-binding protein;Anti-ATP-dependent DNA helicase VIII;Anti-GAP SH3 domain-binding protein 1;Anti-G3BP1 antibody produced in rabbit;Anti-G3BP antibody produced in rabbit;Monoclonal Anti-G3BP antibody produced in mouse;Anti-Ras GTPase-activating protein-binding protein 1
CBNumber
CB32101401
Formula Weight
0
MOL File
Mol file
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Anti-G3BP1, Anti-GAP SH3 domain-binding protein, Anti-HDH-VIII, Anti-human DNA helicase VIII, Anti-Ras-GTPase-activating protein SH3-domain binding protein 1 Property

storage temp. 
-20°C
form 
buffered aqueous glycerol solution
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
WH0010146M1
Product name
Monoclonal Anti-G3BP antibody produced in mouse
Purity
clone 2F3, purified immunoglobulin, buffered aqueous solution
Packaging
100μG
Price
$524
Updated
2024/03/01
Sigma-Aldrich
Product number
SAB4500043
Product name
Anti-G3BP-1 antibody produced in rabbit
Purity
affinity isolated antibody
Packaging
100μG
Price
$506
Updated
2024/03/01
Sigma-Aldrich
Product number
G8046
Product name
Anti-phospho-G3BP (pSer149) antibody produced in rabbit
Purity
~1.0?mg/mL, affinity isolated antibody, buffered aqueous solution
Packaging
200μL
Price
$334.8
Updated
2024/03/01
Sigma-Aldrich
Product number
G6046
Product name
Anti-G3BP antibody produced in rabbit
Purity
~1.0?mg/mL, affinity isolated antibody, buffered aqueous solution
Packaging
200μL
Price
$334.8
Updated
2024/03/01
Sigma-Aldrich
Product number
AV37713
Product name
Anti-G3BP antibody produced in rabbit
Purity
IgG fraction of antiserum
Packaging
100μL
Price
$443
Updated
2024/03/01
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Anti-G3BP1, Anti-GAP SH3 domain-binding protein, Anti-HDH-VIII, Anti-human DNA helicase VIII, Anti-Ras-GTPase-activating protein SH3-domain binding protein 1 Chemical Properties,Usage,Production

Uses

Anti-G3BP antibody produced in rabbit has been used in co-immunoprecipitation assay.

Uses

Anti-phospho-G3BP (pSer149) antibody produced in rabbit is suitable for western blotting at a working concentration of 5-10μg/mL using whole extract of human K562 and HeLa cells.

General Description

G3BP is a RNA-binding protein that contains a RNA binding domain, the RRM-type domain, at the carboxyl-terminal. The N-terminal domain is homologous to nuclear transporter factor 2 (NTF2) and the central domain is rich in acidic residues. The RRM domain is involved in the binding of G3BP to specific RNA sequences. This helps G3BP to function as a CA dinucleotide-specific endoribonuclease. G3BP′s subcellular localization and protein-protein interactions are mediated by the phosphorylation of G3BP at Ser149, near NTF2-like domain. G3BP is found in abundance in many kinds of malignant tumors such as lung, colon, gastric, and breast cancer.

Biochem/physiol Actions

G3BP (Ras-GTPase-activating protein SH3 domain binding protein 1) is a endoribonuclease that is phosphorylation-dependent and specific to single strand. It cleaves between cytosine and adenine (CA). It binds to the SH3 domain of RasGAP. It forms a link between RasGAP-mediated signaling pathway and RNA turnover. G3BP is required for the assembly of stress granules (SGs), which are involved in the regulation of mRNA metabolism during stress. It may be used as a cytoplasmic SG marker.

Anti-G3BP1, Anti-GAP SH3 domain-binding protein, Anti-HDH-VIII, Anti-human DNA helicase VIII, Anti-Ras-GTPase-activating protein SH3-domain binding protein 1 Preparation Products And Raw materials

Raw materials

Preparation Products

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Anti-G3BP1, Anti-GAP SH3 domain-binding protein, Anti-HDH-VIII, Anti-human DNA helicase VIII, Anti-Ras-GTPase-activating protein SH3-domain binding protein 1 Suppliers

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Anti-G3BP1, Anti-GAP SH3 domain-binding protein, Anti-HDH-VIII, Anti-human DNA helicase VIII, Anti-Ras-GTPase-activating protein SH3-domain binding protein 1Related Search:


  • Anti-G3BP antibody produced in rabbit
  • Anti-G3BP1, Anti-GAP SH3 domain-binding protein, Anti-HDH-VIII, Anti-human DNA helicase VIII, Anti-Ras-GTPase-activating protein SH3-domain binding protein 1
  • Anti-phospho-G3BP (pSer149) antibody produced in rabbit
  • Anti-ATP-dependent DNA helicase VIII
  • Anti-G3BP1 antibody produced in rabbit
  • Anti-GAP SH3 domain-binding protein 1
  • Anti-Ras GTPase-activating protein-binding protein 1
  • Anti-Ras-GTPase-activating protein SH3-domain-binding protein
  • Monoclonal Anti-G3BP antibody produced in mouse
  • Anti-G3BP1
  • Anti-GAP SH3 domain-binding protein
  • Anti-HDH-VIII
  • Anti-human DNA helicase VIII
  • Anti-Ras-GTPase-activating protein SH3-domain binding protein 1