(R)-(+)-1-(1-Naphthyl)ethylamine
- Product Name
- (R)-(+)-1-(1-Naphthyl)ethylamine
- CAS No.
- 3886-70-2
- Chemical Name
- (R)-(+)-1-(1-Naphthyl)ethylamine
- Synonyms
- (R)-1-(1-NAPHTHYL)ETHYLAMINE;(R)-1-(NAPHTHALEN-1-YL)ETHANAMINE;CINACALCET intermediate;C12Hj3N;(R)-(+)-ALPH;Cinacalcet-21;RNEA IMPURITY;R-Napthylethylamine;Cinacalce Impurity A;Cinacalcet Impurity A
- CBNumber
- CB3210204
- Molecular Formula
- C12H13N
- Formula Weight
- 171.24
- MOL File
- 3886-70-2.mol
(R)-(+)-1-(1-Naphthyl)ethylamine Property
- Melting point:
- 135-136 °C
- alpha
- 60 º (c=2, CH3OH)
- Boiling point:
- 153 °C11 mm Hg(lit.)
- Density
- 1.067 g/mL at 20 °C(lit.)
- refractive index
- n20/D 1.623(lit.)
- Flash point:
- >230 °F
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
- pka
- 9.26±0.40(Predicted)
- form
- Liquid
- color
- brown
- Specific Gravity
- 1.07
- optical activity
- [α]20/D +55°, c = 2 in ethanol
- Water Solubility
- Soluble in water (<10/l).
- Sensitive
- Air Sensitive
- BRN
- 2208025
- Stability:
- Stable. Air-sensitive. Incompatible with acids, oxidizing agents, acid anhydrides, chloroformates, acid chlorides.
- InChIKey
- RTCUCQWIICFPOD-SECBINFHSA-N
- CAS DataBase Reference
- 3886-70-2(CAS DataBase Reference)
- EPA Substance Registry System
- 1-Naphthalenemethanamine, .alpha.-methyl-, (.alpha.R)- (3886-70-2)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 237442
- Product name
- (R)-(+)-1-(1-Naphthyl)ethylamine
- Purity
- ≥99%
- Packaging
- 1g
- Price
- $66.5
- Updated
- 2024/03/01
- Product number
- 237442
- Product name
- (R)-(+)-1-(1-Naphthyl)ethylamine
- Purity
- ≥99%
- Packaging
- 5g
- Price
- $148
- Updated
- 2024/03/01
- Product number
- N0482
- Product name
- (R)-(+)-1-(1-Naphthyl)ethylamine
- Purity
- >99.0%(GC)
- Packaging
- 1g
- Price
- $43
- Updated
- 2024/03/01
- Product number
- N0482
- Product name
- (R)-(+)-1-(1-Naphthyl)ethylamine
- Purity
- >99.0%(GC)
- Packaging
- 5g
- Price
- $126
- Updated
- 2024/03/01
- Product number
- A16918
- Product name
- (R)-(+)-1-(1-Naphthyl)ethylamine, 99%
- Packaging
- 5g
- Price
- $133.65
- Updated
- 2024/03/01
(R)-(+)-1-(1-Naphthyl)ethylamine Chemical Properties,Usage,Production
Description
(R)-(+)-1-(1-Naphthyl)ethylamine is a reagent used in the formation of isolated acids via salt formation. It is also a raw material for the synthesis of (R)-1-(1-Naphthyl)ethyl isocyanate. In materials research, the use of Reflectance Absorption Infrared Spectroscopy (RAIRS) can be used to study the structure, bonding and orientation of R-1- nea and (S)-(-)-1-(2-naphthyl)ethylamine (S-2- nea) on Pd(1 1 1).
Chemical Properties
Colorless to light yellow liqui
Uses
(R)-(+)-1-(1-Naphthyl)ethylamine is used in chiral synthesis in organic reactions including the synthesis of β-amino acids and the enantioselective of ketones to nitroolefins.
Uses
It is used in chiral synthesis in organic reactions including the synthesis of β-amino acids and the enantioselective of ketones to nitroolefins. Also used as absolute configuration of primary amines determined using chiral (2-nitrophenyl)proline amides and H NMR.
Application
Absolute configuration of primary amines determined using chiral (2-nitrophenyl)proline amides and 1H NMR.
General Description
(R)-(+)-1-(1-Naphthyl)ethylamine is a chiral derivatization reagent useful for all gas chromatography (GC) applications in the chiral field. It is specially selected to meet the requirements for derivatization reagents for enantiomeric excess determinations.
Solubility in organics
(R)-(+)-1-(1-Naphthyl)ethylamine is soluble in chloroform and ethanol. Insoluble in water.
Purification Methods
Purify the amine by distillation in a good vacuum. [Mori et al. Tetrahedron 37 1343 1981, cf Wilson in Topics Stereochem (Allinger and Eliel eds) v o l 6 135 1971, Fredga et al. Acta Chem Scand 11 1609 1957.] The hydrochlorides crystallise from H2O [] D 18 ±3.9o (c 3, H2O), and the sulfates recrystallise from H2O as tetrahydrates m 230-232o. The RS-amine has b 153o/11mm, 156o/15mm, 183.5o/41mm [Blicke & Maxwell J Am Chem Soc 6 1 1780 1939]. [Beilstein 12 III 3111.]
(R)-(+)-1-(1-Naphthyl)ethylamine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (R)-(+)-1-(1-Naphthyl)ethylamine manufacturers
- Product
- (R)-(+)-1-(1-Naphthyl)ethylamine 3886-70-2
- Price
- US $30.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 2000kg
- Release date
- 2024-05-14
- Product
- (R)-(+)-1-(1-Naphthyl)ethylamine 3886-70-2
- Price
- US $0.00-0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 10000KGS
- Release date
- 2021-11-08
- Product
- (R)-(+)-1-(1-Naphthyl)ethylamine 3886-70-2
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 20tons
- Release date
- 2023-10-07