ChemicalBook > CAS DataBase List > Etamsylate

Etamsylate

Product Name
Etamsylate
CAS No.
2624-44-4
Chemical Name
Etamsylate
Synonyms
ETHAMSYLATE;e141;Phenolsulfonate;md141;eselin;HeMsyl;K-Stat;Sylate;altodor;aglumin
CBNumber
CB5165128
Molecular Formula
C10H17NO5S
Formula Weight
263.31
MOL File
2624-44-4.mol
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Etamsylate Property

Melting point:
125°
Density 
1.3441 (rough estimate)
refractive index 
1.5060 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Very soluble in water, freely soluble in methanol, soluble in anhydrous ethanol, practically insoluble in methylene chloride.
form 
Solid
color 
White to Pale Red
Merck 
14,3722
Stability:
Hygroscopic
InChI
InChI=1S/C6H6O5S.C4H11N/c7-4-1-2-5(8)6(3-4)12(9,10)11;1-3-5-4-2/h1-3,7-8H,(H,9,10,11);5H,3-4H2,1-2H3
InChIKey
HBGOLJKPSFNJSD-UHFFFAOYSA-N
SMILES
C1(S(=O)(=O)O)=CC(=CC=C1O)O.N(CC)CC
CAS DataBase Reference
2624-44-4(CAS DataBase Reference)
EPA Substance Registry System
Ethamsylate (2624-44-4)
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Safety

RTECS 
DB6145000
HS Code 
2921.19.6190
HazardClass 
IRRITANT
Toxicity
LD50 i.v. in mice, rats: 800, 1350 mg/kg (Esteve)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P313Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
E1830000
Product name
Etamsylate
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
e1830000
Price
$153
Updated
2024/03/01
TCI Chemical
Product number
E1145
Product name
Etamsylate
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$30
Updated
2024/03/01
TCI Chemical
Product number
E1145
Product name
Etamsylate
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$89
Updated
2024/03/01
TRC
Product number
E889950
Product name
Ethamsylate
Packaging
10mg
Price
$55
Updated
2021/12/16
TRC
Product number
E889950
Product name
Ethamsylate
Packaging
25mg
Price
$70
Updated
2021/12/16
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Etamsylate Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

Haemostatic / Anti Coagulant

Uses

Hemostatic;prostaglandin synthesis inhibitor

Definition

ChEBI: Etamsylate is a sulfonic acid derivative and an organosulfur compound.

Mechanism of action

Etamsylate is an antihaemorrhagic and vasoprotective agent. It increases platelet adhesiveness and capillary vascular wall resistance, thereby reducing capillary exudation and blood loss.

Clinical Use

Short-term treatment of blood loss in menorrhagia
Prophylaxis of surgical bleeding (unlicensed)

Side effects

Significant: Hypotension (parenteral). Rarely, severe hypersensitivity reaction, including anaphylaxis.
Blood and lymphatic system disorders: Parenteral: Rarely, neutropenia, agranulocytosis, thrombocytopenia.
Gastrointestinal disorders: Nausea, vomiting, diarrhoea, abdominal pain or discomfort.
General disorders and administration site conditions: Asthenia (parenteral). Rarely, fever.
Musculoskeletal and connective tissue disorders: Rarely, arthralgia.
Nervous system disorders: Headache.
Skin and subcutaneous tissue disorders: Rash.
Vascular disorders: Rarely, thromboembolism (parenteral).

Metabolism

Etamsylate is excreted unchanged, mainly in the urine.

Etamsylate Preparation Products And Raw materials

Raw materials

Preparation Products

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Etamsylate Suppliers

Jinan Londi Medical Technology Co., LTD
Tel
0531-88996911 15628983711
Fax
0531-88996911
Email
3305202763@qq.com
Country
China
ProdList
125
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Fax
+86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2208
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
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View Lastest Price from Etamsylate manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Etamsylate 2624-44-4
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-21
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Etamsylate 2624-44-4
Price
US $0.00/Kg/Drum
Min. Order
25KG
Purity
99.0%~101.0%; BP2010
Supply Ability
50tons/month
Release date
2021-06-08
Henan Suikang Pharmaceutical Co.,Ltd.
Product
Etamsylate 2624-44-4
Price
US $0.00/kg
Min. Order
1kg
Purity
99.0%
Supply Ability
1tons
Release date
2024-04-26

2624-44-4, EtamsylateRelated Search:


  • altodor
  • e141
  • eselin
  • md141
  • 2,5-dihydroxy-benzenesulfonicacicompd.withdiethylamine
  • 2,5-dihydroxy-benzenesulfonicacicompd.withn-ethylethanamine(1:1)
  • 2,5-dihydroxybenzenesulfonicacidcompd.withn-ethylethanamine
  • 2,5-DihydroxybenzenesulfonicacidcompdwithN-ethylethanamine
  • aglumin
  • ciclonamina
  • cyclonamine
  • dicynene
  • dicynone
  • diethylammonium2,5-dihydroxybenzenesulfonate
  • diethylammoniumcyclohexadien-4-ol-1-one-4-sulfonate
  • diidroxi-1,4-benzenesulfonato-3-di-etilammonium
  • ETAMSYLATE
  • ETHAMSYLATE
  • diethylammonium 2,5-dihydroxybenzenesulphonate
  • Diethylammonium cyclohexadiene-4-ol-1-one-4-sulfonate
  • 2,5-Dihydroxybenzenesulfonic acid N-ethylethanamine
  • N,N-Diethylamine-2,5-dihydroxybenzolsulphonate
  • 2,5-Dihydroxybenzenesulfonic acid diethylamine salt
  • Benzenesulfonic acid, 2,5-dihydroxy-, compd. with diethylamine
  • Benzenesulfonic acid, 2,5-dihydroxy-, compd. with N-ethylethanamine (1:1)
  • Eselin【hemostatic】
  • diethylaMine 2,5-dihydroxybenzenesulfonate
  • 1-hydroxy-4-oxo-2,5-cyclohexadiene-1-sulfonicacidcompd.withdiethylamine
  • EtaMsylate,(S)
  • 2,5-Dihydroxybenzenesulfonic Acid N-EthylethanaMine Salt
  • Biosinon
  • Dicinone
  • HeMsyl
  • K-Stat
  • Sylate
  • EtaMsvlatuM
  • 2,5-Dihydroxybenzenesulfonic acid N-ethylethanamine (1:1)
  • Phenolsulfonate
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  • EtamsylateQ: What is Etamsylate Q: What is the CAS Number of Etamsylate Q: What is the storage condition of Etamsylate Q: What are the applications of Etamsylate
  • Etamsylate API
  • 2,5-Dihydroxybenzenesulfonic acid N-ethylethanamin
  • Methanesulfonic Acid Impurity 8
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  • 2624-44-4
  • Other APIs
  • For the prevention and treatment of bleeding before surgery, but for intestinal bleeding, bleeding and urinary tract bleeding, etc
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