Etamsylate
- Product Name
- Etamsylate
- CAS No.
- 2624-44-4
- Chemical Name
- Etamsylate
- Synonyms
- ETHAMSYLATE;e141;Phenolsulfonate;md141;eselin;HeMsyl;K-Stat;Sylate;altodor;aglumin
- CBNumber
- CB5165128
- Molecular Formula
- C10H17NO5S
- Formula Weight
- 263.31
- MOL File
- 2624-44-4.mol
Etamsylate Property
- Melting point:
- 125°
- Density
- 1.3441 (rough estimate)
- refractive index
- 1.5060 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- Very soluble in water, freely soluble in methanol, soluble in anhydrous ethanol, practically insoluble in methylene chloride.
- form
- Solid
- color
- White to Pale Red
- Merck
- 14,3722
- Stability:
- Hygroscopic
- InChI
- InChI=1S/C6H6O5S.C4H11N/c7-4-1-2-5(8)6(3-4)12(9,10)11;1-3-5-4-2/h1-3,7-8H,(H,9,10,11);5H,3-4H2,1-2H3
- InChIKey
- HBGOLJKPSFNJSD-UHFFFAOYSA-N
- SMILES
- C1(S(=O)(=O)O)=CC(=CC=C1O)O.N(CC)CC
- CAS DataBase Reference
- 2624-44-4(CAS DataBase Reference)
- EPA Substance Registry System
- Ethamsylate (2624-44-4)
Safety
- RTECS
- DB6145000
- HS Code
- 2921.19.6190
- HazardClass
- IRRITANT
- Toxicity
- LD50 i.v. in mice, rats: 800, 1350 mg/kg (Esteve)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P313Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- E1830000
- Product name
- Etamsylate
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- e1830000
- Price
- $153
- Updated
- 2024/03/01
- Product number
- E1145
- Product name
- Etamsylate
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $30
- Updated
- 2024/03/01
- Product number
- E1145
- Product name
- Etamsylate
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $89
- Updated
- 2024/03/01
- Product number
- E889950
- Product name
- Ethamsylate
- Packaging
- 10mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- E889950
- Product name
- Ethamsylate
- Packaging
- 25mg
- Price
- $70
- Updated
- 2021/12/16
Etamsylate Chemical Properties,Usage,Production
Chemical Properties
White Solid
Uses
Haemostatic / Anti Coagulant
Uses
Hemostatic;prostaglandin synthesis inhibitor
Definition
ChEBI: Etamsylate is a sulfonic acid derivative and an organosulfur compound.
Mechanism of action
Etamsylate is an antihaemorrhagic and vasoprotective agent. It increases platelet adhesiveness and capillary vascular wall resistance, thereby reducing capillary exudation and blood loss.
Clinical Use
Short-term treatment of blood loss in menorrhagiaProphylaxis of surgical bleeding (unlicensed)
Side effects
Significant: Hypotension (parenteral). Rarely, severe hypersensitivity reaction, including anaphylaxis.
Blood and lymphatic system disorders: Parenteral: Rarely, neutropenia, agranulocytosis, thrombocytopenia.
Gastrointestinal disorders: Nausea, vomiting, diarrhoea, abdominal pain or discomfort.
General disorders and administration site conditions: Asthenia (parenteral). Rarely, fever.
Musculoskeletal and connective tissue disorders: Rarely, arthralgia.
Nervous system disorders: Headache.
Skin and subcutaneous tissue disorders: Rash.
Vascular disorders: Rarely, thromboembolism (parenteral).
Metabolism
Etamsylate is excreted unchanged, mainly in the urine.
Etamsylate Preparation Products And Raw materials
Raw materials
Preparation Products
Etamsylate Suppliers
- Tel
- --
- Fax
- --
- Country
- France
- ProdList
- 28
- Advantage
- 58
- Tel
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- Fax
- --
- orders@edqm.eu
- Country
- France
- ProdList
- 1913
- Advantage
- 81
View Lastest Price from Etamsylate manufacturers
- Product
- etamsylate 2624-44-4
- Price
- US $80.00/kg
- Min. Order
- 1kg
- Purity
- 99
- Supply Ability
- 5000
- Release date
- 2024-04-23
- Product
- Etamsylate 2624-44-4
- Price
- US $0.00/Kg/Drum
- Min. Order
- 25KG
- Purity
- 99.0%~101.0%; BP2010
- Supply Ability
- 50tons/month
- Release date
- 2021-06-08
- Product
- Etamsylate 2624-44-4
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99.0%
- Supply Ability
- 1tons
- Release date
- 2024-04-26