Tadalafil-d3
- Product Name
- Tadalafil-d3
- CAS No.
- 960226-55-5
- Chemical Name
- Tadalafil-d3
- Synonyms
- Tadalafil-d3;[2H3]-Tadalafil;PubChem ID: 46782966;Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-(methyl-d3)-, (6R,12aR)-;Tadalafil D3Q: What is Tadalafil D3 Q: What is the CAS Number of Tadalafil D3 Q: What is the storage condition of Tadalafil D3 Q: What are the applications of Tadalafil D3
- CBNumber
- CB32104260
- Molecular Formula
- C22H18N3O4
- Formula Weight
- 388.39602
- MOL File
- 960226-55-5.mol
Tadalafil-d3 Property
- Melting point:
- 281-283°C
- storage temp.
- -20°C Freezer
- solubility
- Chloroform (Slightly), DMSO (Slightly)
- form
- Solid
- color
- White to Off-White
- Stability:
- Unstable in Methanol
- InChI
- InChI=1/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21+/s3
- InChIKey
- WOXKDUGGOYFFRN-PDIFIXMTNA-N
- SMILES
- c12c3ccccc3nc1[C@H](c1cc3OCOc3cc1)N1C(=O)CN(C)C(=O)[C@H]1C2 |&1:9,27,r|
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 25030
- Product name
- Tadalafil-d3
- Purity
- ≥99% deuterated forms (d1-d3)
- Packaging
- 1mg
- Price
- $178
- Updated
- 2024/03/01
- Product number
- 25030
- Product name
- Tadalafil-d3
- Purity
- ≥99% deuterated forms (d1-d3)
- Packaging
- 5mg
- Price
- $704
- Updated
- 2024/03/01
- Product number
- T004510
- Product name
- Tadalafil-d3
- Packaging
- 10mg
- Price
- $1390
- Updated
- 2021/12/16
- Product number
- RDL0005317
- Product name
- TADALAFIL-D3
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $1963.5
- Updated
- 2021/12/16
- Product number
- RDL0005317
- Product name
- TADALAFIL-D3
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $750.75
- Updated
- 2021/12/16
Tadalafil-d3 Chemical Properties,Usage,Production
Description
Tadalafil-d3 is intended for use as an internal standard for the quantification of tadalafil by GC- or LC-MS. Tadalafil is a potent inhibitor of phosphodiesterase 5 (PDE5; IC50 = 1.2 nM). It is selective for PDE5 over PDE1-4 and 7-10 (IC50s = 9.2-280 μM), however, it does also inhibit PDE11 (IC50 = 11 nM). In vivo, tadalafil (10 mg/kg) decreases production of the proinflammatory cytokines TNF-α, IL-1β, and IL-6 and improves renal function in a rat model of ischemia/reperfusion injury. It also reduces development of tobacco smoke-induced emphysema and pulmonary hypertension in mice. Formulations containing tadalafil have been used to treat erectile dysfunction, pulmonary arterial hypertension, and lower urinary tract dysfunction.
Chemical Properties
Tadalafil-d3 is White Solid
Uses
Tadalafil-d3 is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor. Intended for use as an internal standard for the quantification of Tadalafil by GC- or LC-mass spectrometry.
Uses
Tadalafil is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.
Tadalafil-d3 Preparation Products And Raw materials
Raw materials
Preparation Products
Tadalafil-d3 Suppliers
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