ChemicalBook > CAS DataBase List > (6R,trans)-6-(3,4-dihydroxyphenyl)-2,3,6,7,12,12a-hexahydro-2-Methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione

(6R,trans)-6-(3,4-dihydroxyphenyl)-2,3,6,7,12,12a-hexahydro-2-Methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione

Product Name
(6R,trans)-6-(3,4-dihydroxyphenyl)-2,3,6,7,12,12a-hexahydro-2-Methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
CAS No.
171489-03-5
Chemical Name
(6R,trans)-6-(3,4-dihydroxyphenyl)-2,3,6,7,12,12a-hexahydro-2-Methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
Synonyms
Tadalafil Catechol;Tadalafil IMpurity K;Tadalafil Impurity 48;Tadalafil Impurity 43;DesMethylene Tadalafil;Tadalafil IMpurity: IMpurity I;Tadalafil Desmethylene Impurity;(6R,12aR)-6-(3,4-dihydroxyphenyl)-2,3,6,7,12,12a-hexahydro-2-Methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione;(6R,trans)-6-(3,4-dihydroxyphenyl)-2,3,6,7,12,12a-hexahydro-2-Methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione;(6R,trans)-6-(3,4-dihydroxyphenyl)-2,3,6,7,12,12a-hexahydro-2-Methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
CBNumber
CB32620915
Molecular Formula
C21H19N3O4
Formula Weight
377.39
MOL File
171489-03-5.mol
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(6R,trans)-6-(3,4-dihydroxyphenyl)-2,3,6,7,12,12a-hexahydro-2-Methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione Property

Melting point:
>215°C (dec.)
Boiling point:
735.3±60.0 °C(Predicted)
Density 
1.56±0.1 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Sparingly), Methanol (Slightly)
pka
9.58±0.10(Predicted)
form 
Solid
color 
Off-White to Light Pink
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
D291990
Product name
DesmethyleneTadalafil
Packaging
5mg
Price
$215
Updated
2021/12/16
Usbiological
Product number
008613
Product name
Desmethylene Tadalafil
Packaging
5mg
Price
$496
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
64170
Product name
DesmethyleneTadalafil
Packaging
50mg
Price
$2400
Updated
2021/12/16
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(6R,trans)-6-(3,4-dihydroxyphenyl)-2,3,6,7,12,12a-hexahydro-2-Methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione Chemical Properties,Usage,Production

Chemical Properties

Off-White to Pale Pink Solid

Uses

Tadalafil. A phosphodiesterase 5 inhibitor.

(6R,trans)-6-(3,4-dihydroxyphenyl)-2,3,6,7,12,12a-hexahydro-2-Methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione Preparation Products And Raw materials

Raw materials

Preparation Products

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(6R,trans)-6-(3,4-dihydroxyphenyl)-2,3,6,7,12,12a-hexahydro-2-Methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione Suppliers

Canada 1 China 32 India 2 United States 2 Global 37
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View Lastest Price from (6R,trans)-6-(3,4-dihydroxyphenyl)-2,3,6,7,12,12a-hexahydro-2-Methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione manufacturers

ShenZhen H&D Pharmaceutical Technology Co., LTD
Product
Tadalafil Catechol 171489-03-5
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
0.98
Supply Ability
10g
Release date
2024-04-25

171489-03-5, (6R,trans)-6-(3,4-dihydroxyphenyl)-2,3,6,7,12,12a-hexahydro-2-Methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dioneRelated Search:

(1S,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester Tadalafil Spiro-urethane IMpurity Tadalafil EP IMpurity G Tadalafil EP Impurity Tadalafil iMpurity E Tadalafil KetolactaM Tadalafil-d3 cis-Tadalafil Tadalafil iMpurity C cis-ent-Tadalafil tadalafi ent-Tadalafil Tadalafil EP IMpurity F Tadalafil iMpurity D Tadalafil EP impurity E N-Ethyl Tadalafil Tadalafil iMpurity I BENZHYDRYL 6,6-DIHYDROPENICILLIC ACID 1-OXIDE[TAZOBACTAM INTERMEDIATE]

  • (6R,12aR)-6-(3,4-dihydroxyphenyl)-2,3,6,7,12,12a-hexahydro-2-Methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
  • (6R,trans)-6-(3,4-dihydroxyphenyl)-2,3,6,7,12,12a-hexahydro-2-Methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
  • DesMethylene Tadalafil
  • Tadalafil IMpurity: IMpurity I
  • Tadalafil IMpurity K
  • Tadalafil Desmethylene Impurity
  • Tadalafil Catechol
  • (6R,12aR)-6-(3,4-Dihydroxyphenyl)-2-methyl-2,3,6,7,12,12a-hexahydro pyrazino [1′,2′:1,6]-pyrido[3,4-b]indole-1,4-dione
  • Tadalafil Impurity 43
  • Tadalafil Impurity 48
  • Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 6-(3,4-dihydroxyphenyl)-2,3,6,7,12,12a-hexahydro-2-methyl-, (6R,12aR)-
  • (6R,trans)-6-(3,4-dihydroxyphenyl)-2,3,6,7,12,12a-hexahydro-2-Methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
  • 171489-03-5
  • Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals