Tadalafil-d3

Product Name: Tadalafil-d3
CAS No.: 960226-55-5
Chemical Name: Tadalafil-d3
Synonyms: Tadalafil-d3;[2H3]-Tadalafil;PubChem ID: 46782966;Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-(methyl-d3)-, (6R,12aR)-;(2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-(2H?)methyl-3,6,17-triazatetracyclo[8.7.0.03,?.011,1?]heptadeca-1(10),11(16),12,14-tetraene-4,7-dione;Tadalafil D3Q: What is Tadalafil D3 Q: What is the CAS Number of Tadalafil D3 Q: What is the storage condition of Tadalafil D3 Q: What are the applications of Tadalafil D3
CBNumber: CB32104260
Molecular Formula: C22H18N3O4
Formula Weight: 388.39602
MOL File: 960226-55-5.mol

More

Less

Tadalafil-d3 Property

Melting point:: 281-283°C
storage temp.: -20°C Freezer
solubility: Chloroform (Slightly), DMSO (Slightly)
form: Solid
color: White to Off-White
Stability:: Unstable in Methanol
InChI: InChI=1/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21+/s3
InChIKey: WOXKDUGGOYFFRN-PDIFIXMTNA-N
SMILES: c12c3ccccc3nc1[C@H](c1cc3OCOc3cc1)N1C(=O)CN(C)C(=O)[C@H]1C2 |&1:9,27,r|

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 25030
Product name: Tadalafil-d3
Purity: ≥99% deuterated forms (d1-d3)
Packaging: 1mg
Price: $178
Updated: 2024/03/01

Cayman Chemical

Product number: 25030
Product name: Tadalafil-d3
Purity: ≥99% deuterated forms (d1-d3)
Packaging: 5mg
Price: $704
Updated: 2024/03/01

TRC

Product number: T004510
Product name: Tadalafil-d3
Packaging: 10mg
Price: $1390
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: RDL0005317
Product name: TADALAFIL-D3
Purity: 95.00%
Packaging: 10MG
Price: $1963.5
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: RDL0005317
Product name: TADALAFIL-D3
Purity: 95.00%
Packaging: 1MG
Price: $750.75
Updated: 2021/12/16

More

Less

Tadalafil-d3 Chemical Properties,Usage,Production

Description

Tadalafil-d₃ is intended for use as an internal standard for the quantification of tadalafil by GC- or LC-MS. Tadalafil is a potent inhibitor of phosphodiesterase 5 (PDE5; IC₅₀ = 1.2 nM). It is selective for PDE5 over PDE1-4 and 7-10 (IC₅₀s = 9.2-280 μM), however, it does also inhibit PDE11 (IC₅₀ = 11 nM). In vivo, tadalafil (10 mg/kg) decreases production of the proinflammatory cytokines TNF-α, IL-1β, and IL-6 and improves renal function in a rat model of ischemia/reperfusion injury. It also reduces development of tobacco smoke-induced emphysema and pulmonary hypertension in mice. Formulations containing tadalafil have been used to treat erectile dysfunction, pulmonary arterial hypertension, and lower urinary tract dysfunction.

Chemical Properties

Tadalafil-d3 is White Solid

Uses

Tadalafil-d3 is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor. Intended for use as an internal standard for the quantification of Tadalafil by GC- or LC-mass spectrometry.

Uses

Tadalafil is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.

Tadalafil-d3 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Tadalafil-d3 Suppliers

Canada 4 China 42 India 4 United States 4 USA 1 Global 55

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Daicel Chiral Technologies (China)CO.,LTD

Tel: 021-50460086-9 15921403865
Fax: +86-21-50462321
Email: han_yajun@dctc.daicel.com
Country: China
ProdList: 7195
Advantage: 65

Cato Research Chemicals Inc.

Tel: 020-81960175
Fax: +1-541-2553641
Email: min.he@cato-chem.com
Country: China
ProdList: 1955
Advantage: 55

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18070
Advantage: 56

Artis Biotech Co. Ltd.

Tel: 0575-18780151478 18582380095
Fax: 0575-89298961
Email: sales@artisbio.com
Country: China
ProdList: 2966
Advantage: 58

Clearsynth Canada Inc.

Tel: +1.415.685.4395
Fax: +1.415.685.4395
Email: enquiry@clearsynth.com
Country: Canada
ProdList: 912
Advantage: 58

Shanghai Champ Biopharmaceuticals Co., Ltd.

Tel: 021-61537865 13585780846
Email: sales@champchem.com
Country: China
ProdList: 360
Advantage: 58

Shenzhen SUNGENING Bio-Medical Co., Ltd.

Tel: 0755-28967200 13631290199
Fax: 0755-28967200
Email: wxf@sungening.com
Country: China
ProdList: 9578
Advantage: 60

Nanjing Haolv Biotechnology Co.,Ltd

Tel: 025-84622273 17361806303
Email: 3004208264@qq.com
Country: China
ProdList: 3021
Advantage: 58

960226-55-5, Tadalafil-d3Related Search:

N-Ethyl Tadalafil Tadalafil EP impurity E Tadalafil iMpurity D Tadalafil EP IMpurity F ent-Tadalafil tadalafi cis-ent-Tadalafil Tadalafil iMpurity C cis-Tadalafil (6R,trans)-6-(3,4-dihydroxyphenyl)-2,3,6,7,12,12a-hexahydro-2-Methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione Tadalafil KetolactaM Tadalafil iMpurity E Tadalafil EP Impurity Tadalafil EP IMpurity G Tadalafil Spiro-urethane IMpurity [13C,2H3]-Tadalafil Tadalafil iMpurity I Tadalafil EP IMpurity A

Tadalafil-d3

Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-(methyl-d3)-, (6R,12aR)-

PubChem ID: 46782966

[2H3]-Tadalafil

Tadalafil D3Q: What is Tadalafil D3 Q: What is the CAS Number of Tadalafil D3 Q: What is the storage condition of Tadalafil D3 Q: What are the applications of Tadalafil D3

(2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-(2H?)methyl-3,6,17-triazatetracyclo[8.7.0.03,?.011,1?]heptadeca-1(10),11(16),12,14-tetraene-4,7-dione

960226-55-5

C22H16N3O4D3

Chiral Reagents

Inhibitors

Intermediates & Fine Chemicals

Isotope Labelled Compounds

Pharmaceuticals

Intermediates & Fine Chemicals,Chiral Reagents